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Chemical Compound Review

Nordolsin     ethyl4-phenylpiperidine-4- carboxylate

Synonyms: nordemerol, Norpethidine, Normeperidine, CHEMBL1052, SureCN341796, ...
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Disease relevance of Pethidine - Intermediate-B


High impact information on Pethidine - Intermediate-B


Chemical compound and disease context of Pethidine - Intermediate-B


Biological context of Pethidine - Intermediate-B


Anatomical context of Pethidine - Intermediate-B


Associations of Pethidine - Intermediate-B with other chemical compounds


Gene context of Pethidine - Intermediate-B


Analytical, diagnostic and therapeutic context of Pethidine - Intermediate-B


  1. Accumulation of normeperidine, an active metabolite of meperidine, in patients with renal failure of cancer. Szeto, H.H., Inturrisi, C.E., Houde, R., Saal, S., Cheigh, J., Reidenberg, M.M. Ann. Intern. Med. (1977) [Pubmed]
  2. Central nervous system excitatory effects of meperidine in cancer patients. Kaiko, R.F., Foley, K.M., Grabinski, P.Y., Heidrich, G., Rogers, A.G., Inturrisi, C.E., Reidenberg, M.M. Ann. Neurol. (1983) [Pubmed]
  3. Presystemic metabolism of meperidine to normeperidine in normal and cirrhotic subjects. Pond, S.M., Tong, T., Benowitz, N.L., Jacob, P., Rigod, J. Clin. Pharmacol. Ther. (1981) [Pubmed]
  4. Antagonism of the convulsant effects of heroin, d-propoxyphene, meperidine, normeperidine and thebaine by naloxone in mice. Gilbert, P.E., Martin, W.R. J. Pharmacol. Exp. Ther. (1975) [Pubmed]
  5. Normeperidine toxicity. Armstrong, P.J., Bersten, A. Anesth. Analg. (1986) [Pubmed]
  6. Meperidine disposition in man: influence of urinary pH and route of administration. Verbeeck, R.K., Branch, R.A., Wilkinson, G.R. Clin. Pharmacol. Ther. (1981) [Pubmed]
  7. A comparison of 50, 100 and 200 mg of intra-articular pethidine during knee joint surgery, a controlled study with evidence for local demethylation to norpethidine. Söderlund, A., Boreus, L.O., Westman, L., Engström, B., Valentin, A., Ekblom, A. Pain (1999) [Pubmed]
  8. Exogenous opioids in human breast milk and acute neonatal neurobehavior: a preliminary study. Wittels, B., Scott, D.T., Sinatra, R.S. Anesthesiology (1990) [Pubmed]
  9. Effects of renal insufficiency on the pharmacokinetics and pharmacodynamics of opioid analgesics. Chan, G.L., Matzke, G.R. Drug intelligence & clinical pharmacy. (1987) [Pubmed]
  10. Subclasses of opioids based on body temperature change in rats: acute subcutaneous administration. Geller, E.B., Hawk, C., Keinath, S.H., Tallarida, R.J., Adler, M.W. J. Pharmacol. Exp. Ther. (1983) [Pubmed]
  11. Pharmacokinetics and analgesic effect of pethidine (meperidine) and its metabolites in the rat. Dahlström, B.E., Paalzow, L.K., Lindberg, C., Bogentoft, C. Drug Metab. Dispos. (1979) [Pubmed]
  12. Determination of pethidine and its major metabolites in human urine by gas chromatography. Chan, K., Lau, O.W., Wong, Y.C. J. Chromatogr. (1991) [Pubmed]
  13. The bioavailability of meperidine using urine assays for meperidine and normeperidine. Stambaugh, J.E., Wainer, I.W. Journal of clinical pharmacology. (1975) [Pubmed]
  14. Norpethidine toxicity and patient controlled analgesia. Stone, P.A., Macintyre, P.E., Jarvis, D.A. British journal of anaesthesia. (1993) [Pubmed]
  15. Disposition of meperidine and normeperidine following multiple doses during labor. II. Fetus and neonate. Kuhnert, B.R., Kuhnert, P.M., Philipson, E.H., Syracuse, C.D. Am. J. Obstet. Gynecol. (1985) [Pubmed]
  16. CYP2B6, CYP3A4, and CYP2C19 are responsible for the in vitro N-demethylation of meperidine in human liver microsomes. Ramírez, J., Innocenti, F., Schuetz, E.G., Flockhart, D.A., Relling, M.V., Santucci, R., Ratain, M.J. Drug Metab. Dispos. (2004) [Pubmed]
  17. Amniotic fluid transfer of meperidine from maternal plasma in early pregnancy. Szeto, H.H., Zervoudakis, I.A., Cederqvist, L.L., Inturrisi, C.E. Obstetrics and gynecology. (1978) [Pubmed]
  18. Radioimmunoassay for normeperidine: studies on the N-dealkylation of meperidine and anileridine. Freeman, D.S., Gjika, H.B., Van Vunakis, H. J. Pharmacol. Exp. Ther. (1977) [Pubmed]
  19. Appearance of pethidine and norpethidine in cerebrospinal fluid of man following intramuscular injection of pethidine. Boréus, L.O., Sköldefors, E., Ehrnebo, M. Acta anaesthesiologica Scandinavica. (1983) [Pubmed]
  20. Meperidine disposition in mother, neonate, and nonpregnant females. Kuhnert, B.R., Kuhnert, P.M., Prochaska, A.L., Sokol, R.J. Clin. Pharmacol. Ther. (1980) [Pubmed]
  21. The clinical pharmacology of meperidine--comparison of routes of administration. Stambaugh, J.E., Wainer, I.W., Sanstead, J.K., Hemphill, D.M. Journal of clinical pharmacology. (1976) [Pubmed]
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