The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Umbilical Cord

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Umbilical Cord


Psychiatry related information on Umbilical Cord


High impact information on Umbilical Cord


Chemical compound and disease context of Umbilical Cord


Biological context of Umbilical Cord


Anatomical context of Umbilical Cord


Associations of Umbilical Cord with chemical compounds


Gene context of Umbilical Cord

  • Enrichment, characterization, and responsiveness of single primitive CD34 human umbilical cord blood hematopoietic progenitors with high proliferative and replating potential [32].
  • The proliferative effects of recombinant human interleukin-3 (IL-3) and granulocyte-macrophage colony-stimulating factor (GM-CSF) were investigated in semi-solid and liquid cultures of purified CD34+ hematopoietic cells obtained from umbilical cord blood [33].
  • Human CD34(+) hematopoietic progenitor cells obtained from bone marrow (BM), umbilical cord blood (UCB), and mobilized peripheral blood (MPB) were purified and investigated for the expression of the chemokine receptor CXCR4 and its ligand, stromal cell-derived factor-1 (SDF-1) [34].
  • To study human NK cell receptor ontogeny, umbilical cord blood CD34(+)/Lin(-)/CD38(-) cells were cultured with a murine fetal liver line (AFT024) and defined cytokines [35].
  • Retroviral transduction of Smad7 into human umbilical cord blood (CB)-SRCs caused a shift from lymphoid dominant engraftment toward increased myeloid contribution, and increased the myeloid-committed clonogenic progenitor frequency in reconstituted mice [36].

Analytical, diagnostic and therapeutic context of Umbilical Cord


  1. Anuria, omphalocele, and perinatal lethality in mice lacking the CD34-related protein podocalyxin. Doyonnas, R., Kershaw, D.B., Duhme, C., Merkens, H., Chelliah, S., Graf, T., McNagny, K.M. J. Exp. Med. (2001) [Pubmed]
  2. Upregulated expression and function of integrin adhesive receptors in systemic lupus erythematosus patients with vasculitis. Takeuchi, T., Amano, K., Sekine, H., Koide, J., Abe, T. J. Clin. Invest. (1993) [Pubmed]
  3. Transplantation of human umbilical cord blood cells in macrophage-depleted SCID mice: evidence for accessory cell involvement in expansion of immature CD34+CD38- cells. Verstegen, M.M., van Hennik, P.B., Terpstra, W., van den Bos, C., Wielenga, J.J., van Rooijen, N., Ploemacher, R.E., Wagemaker, G., Wognum, A.W. Blood (1998) [Pubmed]
  4. Enhanced megakaryocyte and erythroid development from normal human CD34(+) cells: consequence of enforced expression of SCL. Elwood, N.J., Zogos, H., Pereira, D.S., Dick, J.E., Begley, C.G. Blood (1998) [Pubmed]
  5. Synthesis and expression of C1 inhibitor by human umbilical vein endothelial cells. Schmaier, A.H., Murray, S.C., Heda, G.D., Farber, A., Kuo, A., McCrae, K., Cines, D.B. J. Biol. Chem. (1989) [Pubmed]
  6. Human umbilical cord blood cells ameliorate Alzheimer's disease in transgenic mice. Ende, N., Chen, R., Ende-Harris, D. Journal of medicine. (2001) [Pubmed]
  7. Hematopoietic stem-cell transplants using umbilical-cord blood. Gluckman, E. N. Engl. J. Med. (2001) [Pubmed]
  8. Circulating erythroid progenitors in the anemia of prematurity. Shannon, K.M., Naylor, G.S., Torkildson, J.C., Clemons, G.K., Schaffner, V., Goldman, S.L., Lewis, K., Bryant, P., Phibbs, R. N. Engl. J. Med. (1987) [Pubmed]
  9. Vertical transmission of hepatitis B antigen in Taiwan. Stevens, C.E., Beasley, R.P., Tsui, J., Lee, W.C. N. Engl. J. Med. (1975) [Pubmed]
  10. Engraftment of gene-modified umbilical cord blood cells in neonates with adenosine deaminase deficiency. Kohn, D.B., Weinberg, K.I., Nolta, J.A., Heiss, L.N., Lenarsky, C., Crooks, G.M., Hanley, M.E., Annett, G., Brooks, J.S., el-Khoureiy, A. Nat. Med. (1995) [Pubmed]
  11. Direct evidence of sudden rise in fetal corticoids late in human gestation. Fencl, M.D., Stillman, R.J., Cohen, J., Tulchinsky, D. Nature (1980) [Pubmed]
  12. Preeclampsia is associated with low circulating levels of insulin-like growth factor I and 1,25-dihydroxyvitamin D in maternal and umbilical cord compartments. Halhali, A., Tovar, A.R., Torres, N., Bourges, H., Garabedian, M., Larrea, F. J. Clin. Endocrinol. Metab. (2000) [Pubmed]
  13. Extracellular glutamate levels and neuropathology in cerebral white matter following repeated umbilical cord occlusion in the near term fetal sheep. Loeliger, M., Watson, C.S., Reynolds, J.D., Penning, D.H., Harding, R., Bocking, A.D., Rees, S.M. Neuroscience (2003) [Pubmed]
  14. Hypoxanthine as a measurement of hypoxia. Saugstad, O.D. Pediatr. Res. (1975) [Pubmed]
  15. Deficient priming activity of newborn cord blood-derived polymorphonuclear neutrophilic granulocytes with lipopolysaccharide and tumor necrosis factor-alpha triggered with formyl-methionyl-leucyl-phenylalanine. Bortolussi, R., Howlett, S., Rajaraman, K., Halperin, S. Pediatr. Res. (1993) [Pubmed]
  16. Idarubicinol myelotoxicity: a comparison of in vitro data with clinical outcome in patients treated with high-dose idarubicin. Corsini, C., Ghielmini, M., Mancuso, P., Tealdo, F., Paolucci, M., Zucchetti, M., Ferrucci, P.F., Cocorocchio, E., Mezzetti, M., Mori, A., Riggi, M., D'Incalci, M., Martinelli, G. Br. J. Cancer (2000) [Pubmed]
  17. Functional neurokinin 1 receptors for substance P are expressed by human vascular endothelium. Greeno, E.W., Mantyh, P., Vercellotti, G.M., Moldow, C.F. J. Exp. Med. (1993) [Pubmed]
  18. A widely expressed human protein-tyrosine phosphatase containing src homology 2 domains. Ahmad, S., Banville, D., Zhao, Z., Fischer, E.H., Shen, S.H. Proc. Natl. Acad. Sci. U.S.A. (1993) [Pubmed]
  19. CD34+CD38dim cells in the human thymus can differentiate into T, natural killer, and dendritic cells but are distinct from pluripotent stem cells. Res, P., Martínez-Cáceres, E., Cristina Jaleco, A., Staal, F., Noteboom, E., Weijer, K., Spits, H. Blood (1996) [Pubmed]
  20. Integrin-mediated adhesion of endothelial cells induces JAK2 and STAT5A activation: role in the control of c-fos gene expression. Brizzi, M.F., Defilippi, P., Rosso, A., Venturino, M., Garbarino, G., Miyajima, A., Silengo, L., Tarone, G., Pegoraro, L. Mol. Biol. Cell (1999) [Pubmed]
  21. Umbilical venous IGF-1 concentration, neonatal bone mass, and body composition. Javaid, M.K., Godfrey, K.M., Taylor, P., Shore, S.R., Breier, B., Arden, N.K., Cooper, C. J. Bone Miner. Res. (2004) [Pubmed]
  22. Membrane Fas ligand kills human peripheral blood T lymphocytes, and soluble Fas ligand blocks the killing. Suda, T., Hashimoto, H., Tanaka, M., Ochi, T., Nagata, S. J. Exp. Med. (1997) [Pubmed]
  23. Metabolism of vasoactive peptides by human endothelial cells in culture. Angiotensin I converting enzyme (kininase II) and angiotensinase. Johnson, A.R., Erdös, E.G. J. Clin. Invest. (1977) [Pubmed]
  24. Untying the Gordian knot: policies, practices, and ethical issues related to banking of umbilical cord blood. Kurtzberg, J., Lyerly, A.D., Sugarman, J. J. Clin. Invest. (2005) [Pubmed]
  25. Recombinant interleukin-12 suppresses the synthesis of immunoglobulin E by interleukin-4 stimulated human lymphocytes. Kiniwa, M., Gately, M., Gubler, U., Chizzonite, R., Fargeas, C., Delespesse, G. J. Clin. Invest. (1992) [Pubmed]
  26. The C-C chemokine receptor CCR3 participates in stimulation of eosinophil arrest on inflammatory endothelium in shear flow. Kitayama, J., Mackay, C.R., Ponath, P.D., Springer, T.A. J. Clin. Invest. (1998) [Pubmed]
  27. Methylmercury and selenium in umbilical cords of inhabitants of the Minamata area. Nishigaki, S., Harada, M. Nature (1975) [Pubmed]
  28. Inverse relation between low-density lipoprotein-cholesterol and dehydroisoandrosterone sulfate in human fetal plasma. Parker, C.R., Simpson, E.R., Bilheimer, D.W., Leveno, K., Carr, B.R., MacDonald, P.C. Science (1980) [Pubmed]
  29. Fetal and neonatal hazards of maternal hydration with 5% dextrose before caesarean section. Kenepp, N.B., Kumar, S., Shelley, W.C., Stanley, C.A., Gabbe, S.G., Gutsche, B.B. Lancet (1982) [Pubmed]
  30. Detection of house-dust-mite allergen in amniotic fluid and umbilical-cord blood. Holloway, J.A., Warner, J.O., Vance, G.H., Diaper, N.D., Warner, J.A., Jones, C.A. Lancet (2000) [Pubmed]
  31. Purification of folate binding factor in normal umbilical cord serum. Kamen, B.A., Caston, J.D. Proc. Natl. Acad. Sci. U.S.A. (1975) [Pubmed]
  32. Enrichment, characterization, and responsiveness of single primitive CD34 human umbilical cord blood hematopoietic progenitors with high proliferative and replating potential. Lu, L., Xiao, M., Shen, R.N., Grigsby, S., Broxmeyer, H.E. Blood (1993) [Pubmed]
  33. Combined and sequential effects of human IL-3 and GM-CSF on the proliferation of CD34+ hematopoietic cells from cord blood. Saeland, S., Caux, C., Favre, C., Duvert, V., Pébusque, M.J., Mannoni, P., deVries, J.E. Blood (1989) [Pubmed]
  34. Human CD34(+) cells express CXCR4 and its ligand stromal cell-derived factor-1. Implications for infection by T-cell tropic human immunodeficiency virus. Aiuti, A., Turchetto, L., Cota, M., Cipponi, A., Brambilla, A., Arcelloni, C., Paroni, R., Vicenzi, E., Bordignon, C., Poli, G. Blood (1999) [Pubmed]
  35. Human natural killer cells with polyclonal lectin and immunoglobulinlike receptors develop from single hematopoietic stem cells with preferential expression of NKG2A and KIR2DL2/L3/S2. Miller, J.S., McCullar, V. Blood (2001) [Pubmed]
  36. Smad7 alters cell fate decisions of human hematopoietic repopulating cells. Chadwick, K., Shojaei, F., Gallacher, L., Bhatia, M. Blood (2005) [Pubmed]
  37. Transplanted cord blood-derived endothelial precursor cells augment postnatal neovascularization. Murohara, T., Ikeda, H., Duan, J., Shintani, S., Sasaki, K., Eguchi, H., Onitsuka, I., Matsui, K., Imaizumi, T. J. Clin. Invest. (2000) [Pubmed]
  38. Support of human cord blood progenitor cells on human stromal cell lines transformed by SV40 large T antigen under the influence of an inducible (metallothionein) promoter. Cicuttini, F.M., Martin, M., Salvaris, E., Ashman, L., Begley, C.G., Novotny, J., Maher, D., Boyd, A.W. Blood (1992) [Pubmed]
  39. Unrelated donor hematopoietic cell transplantation: marrow or umbilical cord blood? Grewal, S.S., Barker, J.N., Davies, S.M., Wagner, J.E. Blood (2003) [Pubmed]
  40. Oral zidovudine during labor to prevent perinatal HIV transmission, Bangkok: tolerance and zidovudine concentration in cord blood. Bangkok Collaborative Perinatal HIV Transmission Study Group. Bhadrakom, C., Simonds, R.J., Mei, J.V., Asavapiriyanont, S., Sangtaweesin, V., Vanprapar, N., Moore, K.H., Young, N.L., Hannon, W.H., Mastro, T.D., Shaffer, N. AIDS (2000) [Pubmed]
  41. Tnk1: a novel intracellular tyrosine kinase gene isolated from human umbilical cord blood CD34+/Lin-/CD38- stem/progenitor cells. Hoehn, G.T., Stokland, T., Amin, S., Ramírez, M., Hawkins, A.L., Griffin, C.A., Small, D., Civin, C.I. Oncogene (1996) [Pubmed]
WikiGenes - Universities