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Chemical Compound Review

PeCDF     2,3,4,7,8- pentachlorodibenzofuran

Synonyms: CHEMBL335558, PCDF 114, CCRIS 3492, AG-G-01259, SureCN2281485, ...
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Disease relevance of 4-PeCDF


High impact information on 4-PeCDF


Chemical compound and disease context of 4-PeCDF


Biological context of 4-PeCDF


Anatomical context of 4-PeCDF


Associations of 4-PeCDF with other chemical compounds


Gene context of 4-PeCDF

  • With TCDD as the reference standard, relative potency (REP) estimates were derived from ratios of the BMD10 estimates for PCB 126, 4-PeCDF, and for the toxic equivalent (TEQ) mixture [14].
  • We investigated the cell toxicity of polychlorinated biphenyls (PCBs) and 2,3,4,7,8-pentachlorodibenzofuran (PCDF) as an indicator of the quantity of m-RNA, which synthesizes the HBV core antigen region, and secreting protein, which is an HBV surface antigen in PLC/PRF/5 cells [10].


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  8. Multimedia fate and human intake modeling: spatial versus nonspatial insights for chemical emissions in Western Europe. Pennington, D.W., Margni, M., Ammann, C., Jolliet, O. Environ. Sci. Technol. (2005) [Pubmed]
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  10. In vitro analysis of polychlorinated biphenyls (PCBs) and 2,3,4,7,8-pentachlorodibenzofuran (PCDF) cellular toxicity in PLC/PRF/5 cell proliferation--the effect of ursodeoxycholic acid, inchin-gorei-san and shou-saiko-to on cell toxicity. Matsuoka, K., Nonaka, S., Ohgami, T., Yoshida, H., Murayama, F. Fukuoka Igaku Zasshi (1991) [Pubmed]
  11. Teratogenic effects of polychlorinated dibenzofurans in combination in C57BL/6N mice. Birnbaum, L.S., Harris, M.W., Crawford, D.D., Morrissey, R.E. Toxicol. Appl. Pharmacol. (1987) [Pubmed]
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  13. The relative abilities of TCDD and its congeners to induce oxidative stress in the hepatic and brain tissues of rats after subchronic exposure. Hassoun, E.A., Li, F., Abushaban, A., Stohs, S.J. Toxicology (2000) [Pubmed]
  14. Relative cancer potencies of selected dioxin-like compounds on a body-burden basis: comparison to current toxic equivalency factors (TEFs). Gray, M.N., Aylward, L.L., Keenan, R.E. J. Toxicol. Environ. Health Part A (2006) [Pubmed]
  15. Metabolism of benzo(a)pyrene by lung microsomes from rabbits pretreated with polychlorinated biphenyls and 2,3,4,7,8-pentachlorodibenzofuran. Ueng, T.H., Alvares, A.P. Life Sci. (1993) [Pubmed]
  16. Purification and characterization of two forms of 2,3,4,7,8-pentachlorodibenzofuran-inducible cytochrome P-450 in hamster liver. Koga, N., Ariyoshi, N., Nakashima, H., Yoshimura, H. J. Biochem. (1990) [Pubmed]
  17. Comparative dermal absorption of 2,3,7,8-tetrachlorodibenzo-p-dioxin and three polychlorinated dibenzofurans. Brewster, D.W., Banks, Y.B., Clark, A.M., Birnbaum, L.S. Toxicol. Appl. Pharmacol. (1989) [Pubmed]
  18. Polychlorinated dibenzo-p-dioxin/polychlorinated dibenzofuran releases into the atmosphere from the use of secondary fuels in cement kilns during clinker formation. Abad, E., Martínez, K., Caixach, J., Rivera, J. Environ. Sci. Technol. (2004) [Pubmed]
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