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Disease relevance of Trichophyton


High impact information on Trichophyton

  • In addition, a novel Trichophyton allergen, encoding 412 amino acids, was identified by its human IgE antibody-binding activity [6].
  • It has been shown by us and others that progesterone inhibits the growth of Trichophyton mentagrophytes and that the organism escapes from this inhibition over time [7].
  • Successful use of ketoconazole for invasive cutaneous Trichophyton rubrum infection [8].
  • BACKGROUND: It has been proposed that Trichophyton infection is associated with atopy and allergy [1].
  • RESULTS: At the end of the first 5 months of active treatment, there was a highly significant decrease in bronchial sensitivity to Trichophyton (P =.012) and in oral steroid requirement (P =.01) [9].

Chemical compound and disease context of Trichophyton


Biological context of Trichophyton


Anatomical context of Trichophyton


Associations of Trichophyton with chemical compounds


Gene context of Trichophyton


Analytical, diagnostic and therapeutic context of Trichophyton


  1. Trichophyton-specific IgE in patients with dermatophytosis is not associated with aeroallergen sensitivity. Escalante, M.T., Sánchez-Borges, M., Capriles-Hulett, A., Belfort, E., Di Biagio, E., González-Aveledo, L. J. Allergy Clin. Immunol. (2000) [Pubmed]
  2. Butenafine. McNeely, W., Spencer, C.M. Drugs (1998) [Pubmed]
  3. Suppression of cellular immune activity following severe head injury. Quattrocchi, K.B., Frank, E.H., Miller, C.H., MacDermott, J.P., Hein, L., Frey, L., Wagner, F.C. J. Neurotrauma (1990) [Pubmed]
  4. A method for the determination of drug effectiveness in onychomycosis. Trials with ketoconazole and griseofulvin ultramicrosize. Zaias, N., Drachman, D. J. Am. Acad. Dermatol. (1983) [Pubmed]
  5. Mismatched double-stranded RNA, Ampligen (poly(I): poly(C12U), demonstrates antiviral and immunostimulatory activities in HIV disease. Carter, W.A., Ventura, D., Shapiro, D.E., Strayer, D.R., Gillespie, D.H., Hubbell, H.R. Int. J. Immunopharmacol. (1991) [Pubmed]
  6. Trichophyton antigens associated with IgE antibodies and delayed type hypersensitivity. Sequence homology to two families of serine proteinases. Woodfolk, J.A., Wheatley, L.M., Piyasena, R.V., Benjamin, D.C., Platts-Mills, T.A. J. Biol. Chem. (1998) [Pubmed]
  7. Steroid metabolism as a mechanism of escape from progesterone-mediated growth inhibition in Trichophyton mentagrophytes. Clemons, K.V., Stover, E.P., Schär, G., Stathis, P.A., Chan, K., Tökès, L., Stevens, D.A., Feldman, D. J. Biol. Chem. (1989) [Pubmed]
  8. Successful use of ketoconazole for invasive cutaneous Trichophyton rubrum infection. Baker, R.L., Para, M.F. Arch. Intern. Med. (1984) [Pubmed]
  9. Treatment of late-onset asthma with fluconazole. Ward, G.W., Woodfolk, J.A., Hayden, M.L., Jackson, S., Platts-Mills, T.A. J. Allergy Clin. Immunol. (1999) [Pubmed]
  10. Effects of butenafine hydrochloride, a new benzylamine derivative, on experimental dermatophytosis in guinea pigs. Arika, T., Yokoo, M., Hase, T., Maeda, T., Amemiya, K., Yamaguchi, H. Antimicrob. Agents Chemother. (1990) [Pubmed]
  11. Epidermal cell proliferation in guinea pigs with experimental dermatophytosis. Tagami, H. J. Invest. Dermatol. (1985) [Pubmed]
  12. Management of onychomycosis with oral terbinafine. Zaias, N. J. Am. Acad. Dermatol. (1990) [Pubmed]
  13. Tinea capitis: itraconazole in Trichophyton tonsurans infection. Elewski, B.E. J. Am. Acad. Dermatol. (1994) [Pubmed]
  14. Once weekly fluconazole is effective in children in the treatment of tinea capitis: a prospective, multicentre study. Gupta, A.K., Dlova, N., Taborda, P., Morar, N., Taborda, V., Lynde, C.W., Konnikov, N., Borges, M., Raboobee, N., Summerbell, R.C., Adam, P., Hofstader, S.L., Aboobaker, J. Br. J. Dermatol. (2000) [Pubmed]
  15. Trichophyton tonsurans allergen. I. Characterization of a protein that causes immediate but not delayed hypersensitivity. Deuell, B., Arruda, L.K., Hayden, M.L., Chapman, M.D., Platts-Mills, T.A. J. Immunol. (1991) [Pubmed]
  16. Chronic dermatophyte infection: evaluation of the Ig class-specific antibody response reactive with polysaccharide and peptide antigens derived from Trichophyton mentagrophytes. Honbo, S., Jones, H.E., Artis, W.M. J. Invest. Dermatol. (1984) [Pubmed]
  17. Differential inhibition of fungal amd mammalian squalene epoxidases by the benzylamine SDZ SBA 586 in comparison with the allylamine terbinafine. Favre, B., Ryder, N.S. Arch. Biochem. Biophys. (1997) [Pubmed]
  18. Differences among chitin synthase I gene sequences in Trichophyton rubrum and T. violaceum. Kano, R., Okabayashi, K., Nakamura, Y., Ooka, S., Kashima, M., Mizoguchi, M., Watanabe, S., Hasegawa, A. Med. Mycol. (2000) [Pubmed]
  19. Delayed hypersensitivity skin testing in elective colorectal surgery and relationship to postoperative sepsis. Griffith, C.D., Ross, A.H. JPEN. Journal of parenteral and enteral nutrition. (1984) [Pubmed]
  20. Treatment with itraconazole of widespread tinea corporis due to Trichophyton rubrum in a bone marrow transplant recipient. Engelhard, D., Or, R., Naparstek, E., Leibovici, V. Bone Marrow Transplant. (1988) [Pubmed]
  21. Effect of hydrocortisone on Trichophyton rubrum growth in human epidermal keratinocyte cultures. Liu, S.C., Jacobs, P.H. Cutis; cutaneous medicine for the practitioner. (1985) [Pubmed]
  22. Effects of different temperatures on cell wall formation and polysaccharide arrangement in Trichophyton mentagrophytes: considerations from a cytochemical study. Vannini, G.L. J. Ultrastruct. Res. (1979) [Pubmed]
  23. Autophagic vacuole development in Trichophyton mentagrophytes exposed in vitro to miconazole. Masperi, P., Dall'Olio, G., Calefano, A., Vannini, G.L. Sabouraudia. (1984) [Pubmed]
  24. Clinical Trichophyton rubrum strain exhibiting primary resistance to terbinafine. Mukherjee, P.K., Leidich, S.D., Isham, N., Leitner, I., Ryder, N.S., Ghannoum, M.A. Antimicrob. Agents Chemother. (2003) [Pubmed]
  25. Effects of antifungal agents on ergosterol biosynthesis in Candida albicans and Trichophyton mentagrophytes: differential inhibitory sites of naphthiomate and miconazole. Morita, T., Nozawa, Y. J. Invest. Dermatol. (1985) [Pubmed]
  26. In vitro antifungal activity of KP-103, a novel triazole derivative, and its therapeutic efficacy against experimental plantar tinea pedis and cutaneous candidiasis in guinea pigs. Tatsumi, Y., Yokoo, M., Arika, T., Yamaguchi, H. Antimicrob. Agents Chemother. (2001) [Pubmed]
  27. Antifungal properties of 2-bromo-3-fluorosuccinic acid esters and related compounds. Gershon, H., Shanks, L. J. Med. Chem. (1977) [Pubmed]
  28. Mitochondrial DNA sequence analysis of the cytochrome oxidase subunit I and II genes, the ATPase9 gene, the NADH dehydrogenase ND4L and ND5 gene complex, and the glutaminyl, methionyl and arginyl tRNA genes from Trichophyton rubrum. de Bièvre, C., Dujon, B. Curr. Genet. (1992) [Pubmed]
  29. Development of the primer set for the detection of the hsp60 gene in Trichophyton mentagrophytes cDNA. Kopecek, P., Raska, M., Weigl, E. Folia Microbiol. (Praha) (1999) [Pubmed]
  30. Repeated ubiquitin genes in Trichophyton mentagrophytes. Kano, R., Nakamura, Y., Watanabe, S., Hasegawa, A. Curr. Microbiol. (1999) [Pubmed]
  31. Inhibition of growth of Trichophyton rubrum by the myeloperoxidase-hydrogen peroxide-chloride system. MacCarthy, K.G., Dahl, M.V. J. Invest. Dermatol. (1989) [Pubmed]
  32. Strain identification of Trichophyton rubrum by specific amplification of subrepeat elements in the ribosomal DNA nontranscribed spacer. Jackson, C.J., Barton, R.C., Kelly, S.L., Evans, E.G. J. Clin. Microbiol. (2000) [Pubmed]
  33. Serum IgE antibodies to Trichophyton in patients with urticaria, angioedema, asthma, and rhinitis: development of a radioallergosorbent test. Platts-Mills, T.A., Fiocco, G.P., Hayden, M.L., Guerrant, J.L., Pollart, S.M., Wilkins, S.R. J. Allergy Clin. Immunol. (1987) [Pubmed]
  34. Molecular cloning and characterization of a novel ABC transporter gene in the human pathogen Trichophyton rubrum. Cervelatti, E.P., Fachin, A.L., Ferreira-Nozawa, M.S., Martinez-Rossi, N.M. Med. Mycol. (2006) [Pubmed]
  35. Evaluation of the anti-Trichophyton activity of a prodigiosin analogue produced by gamma-proteobacterium, using stratum corneum epidermis of the Yucatan micropig. Nakashima, T., Kato, Y., Yamaguchi, K., Oda, T. J. Infect. Chemother. (2005) [Pubmed]
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