Gene Review:
CELF2 - CUGBP, Elav-like family member 2
Homo sapiens
Synonyms:
BRUNOL3, Bruno-like protein 3, CELF-2, CUG triplet repeat RNA-binding protein 2, CUG-BP-and ETR-3-like factor 2, ...
- CUGBP2 plays a critical role in apoptosis of breast cancer cells in response to genotoxic injury. Mukhopadhyay, D., Jung, J., Murmu, N., Houchen, C.W., Dieckgraefe, B.K., Anant, S. Ann. N. Y. Acad. Sci. (2003)
- Expression and mutation analysis of BRUNOL3, a candidate gene for heart and thymus developmental defects associated with partial monosomy 10p. Lichtner, P., Attié-Bitach, T., Schuffenhauer, S., Henwood, J., Bouvagnet, P., Scambler, P.J., Meitinger, T., Vekemans, M. J. Mol. Med. (2002)
- ETR-3 represses Tau exons 2/3 inclusion, a splicing event abnormally enhanced in myotonic dystrophy type I. Leroy, O., Dhaenens, C.M., Schraen-Maschke, S., Belarbi, K., Delacourte, A., Andreadis, A., Sablonnière, B., Buée, L., Sergeant, N., Caillet-Boudin, M.L. J. Neurosci. Res. (2006)
- Genomic organization and isoform-specific tissue expression of human NAPOR (CUGBP2) as a candidate gene for familial arrhythmogenic right ventricular dysplasia. Li, D., Bachinski, L.L., Roberts, R. Genomics (2001)
- Coupled mRNA stabilization and translational silencing of cyclooxygenase-2 by a novel RNA binding protein, CUGBP2. Mukhopadhyay, D., Houchen, C.W., Kennedy, S., Dieckgraefe, B.K., Anant, S. Mol. Cell (2003)
- Dynamic antagonism between ETR-3 and PTB regulates cell type-specific alternative splicing. Charlet-B, N., Logan, P., Singh, G., Cooper, T.A. Mol. Cell (2002)
- Functional Antagonism Between RNA Binding Proteins HuR and CUGBP2 Determines the Fate of COX-2 mRNA Translation. Sureban, S.M., Murmu, N., Rodriguez, P., May, R., Maheshwari, R., Dieckgraefe, B.K., Houchen, C.W., Anant, S. Gastroenterology (2007)
- Novel role for RNA-binding protein CUGBP2 in mammalian RNA editing. CUGBP2 modulates C to U editing of apolipoprotein B mRNA by interacting with apobec-1 and ACF, the apobec-1 complementation factor. Anant, S., Henderson, J.O., Mukhopadhyay, D., Navaratnam, N., Kennedy, S., Min, J., Davidson, N.O. J. Biol. Chem. (2001)
- A web-accessible complete transcriptome of normal human and DMD muscle. Bakay, M., Zhao, P., Chen, J., Hoffman, E.P. Neuromuscul. Disord. (2002)
- Identification of putative new splicing targets for ETR-3 using sequences identified by systematic evolution of ligands by exponential enrichment. Faustino, N.A., Cooper, T.A. Mol. Cell. Biol. (2005)
- ApoB mRNA editing is mediated by a coordinated modulation of multiple apoB mRNA editing enzyme components. Chen, Z., Eggerman, T.L., Patterson, A.P. Am. J. Physiol. Gastrointest. Liver Physiol. (2007)
- Dynamic antagonism between RNA-binding protein CUGBP2 and cyclooxygenase-2-mediated prostaglandin E2 in radiation damage. Murmu, N., Jung, J., Mukhopadhyay, D., Houchen, C.W., Riehl, T.E., Stenson, W.F., Morrison, A.R., Arumugam, T., Dieckgraefe, B.K., Anant, S. Proc. Natl. Acad. Sci. U.S.A. (2004)
- Differential expression of three genes encoding an ethylene receptor in rice during development, and in response to indole-3-acetic acid and silver ions. Yau, C.P., Wang, L., Yu, M., Zee, S.Y., Yip, W.K. J. Exp. Bot. (2004)
- Discovery of a novel compound: insight into mechanisms for acrylamide-induced axonopathy and colchicine-induced apoptotic neuronal cell death. Nakagawa-Yagi, Y., Choi, D.K., Ogane, N., Shimada, S., Seya, M., Momoi, T., Ito, T., Sakaki, Y. Brain Res. (2001)
- Identification of CELF splicing activation and repression domains in vivo. Han, J., Cooper, T.A. Nucleic Acids Res. (2005)
- Mammalian CELF/Bruno-like RNA-binding proteins: molecular characteristics and biological functions. Barreau, C., Paillard, L., Méreau, A., Osborne, H.B. Biochimie (2006)
- Expression profiling in spinal muscular atrophy reveals an RNA binding protein deficit. Anderson, K.N., Baban, D., Oliver, P.L., Potter, A., Davies, K.E. Neuromuscul. Disord. (2004)