Gene Review:
Pheo - pheomelanin
Mus musculus
Hirobe,
Takeuchi,
Hotta,
Wakamatsu,
Ito,
Kanetsky,
Swoyer,
Panossian,
Holmes,
Guerry,
Rebbeck,
Hirobe,
Wakamatsu,
Ito,
Abe,
Kawa,
Mizoguchi,
Suto,
Wakamatsu,
Yamanaka,
Ito,
Sekikawa,
Ito,
Wakamatsu,
Matsunaga,
Hearing,
Carey,
Anderson,
Dooley,
Hill,
Hill,
Hirobe,
Wakamatsu,
Ito,
Kawa,
Soma,
Mizoguchi,
- Melanin acts as a potent UVB photosensitizer to cause an atypical mode of cell death in murine skin. Takeuchi, S., Zhang, W., Wakamatsu, K., Ito, S., Hearing, V.J., Kraemer, K.H., Brash, D.E. Proc. Natl. Acad. Sci. U.S.A. (2004)
- Effects of ultraviolet-visible irradiation in the presence of melanin isolated from human black or red hair upon Ehrlich ascites carcinoma cells. Menon, I.A., Persad, S., Ranadive, N.S., Haberman, H.F. Cancer Res. (1983)
- Quantitative analysis of eumelanin and pheomelanin in hair and melanomas. Ito, S., Jimbow, K. J. Invest. Dermatol. (1983)
- Stimulation of pheomelanogenesis in cultured B16 melanoma cells by 4-tertiary butylcatechol. Kawashima, T., Halldin, M.M., Fukuyama, K., Castagnoli, N., Gellin, G.A., Epstein, W.L. Biochem. Pharmacol. (1985)
- Noise-induced hearing loss: the effect of melanin in the stria vascularis. Bartels, S., Ito, S., Trune, D.R., Nuttall, A.L. Hear. Res. (2001)
- Modulation of murine melanocyte function in vitro by agouti signal protein. Sakai, C., Ollmann, M., Kobayashi, T., Abdel-Malek, Z., Muller, J., Vieira, W.D., Imokawa, G., Barsh, G.S., Hearing, V.J. EMBO J. (1997)
- Slc7a11 gene controls production of pheomelanin pigment and proliferation of cultured cells. Chintala, S., Li, W., Lamoreux, M.L., Ito, S., Wakamatsu, K., Sviderskaya, E.V., Bennett, D.C., Park, Y.M., Gahl, W.A., Huizing, M., Spritz, R.A., Ben, S., Novak, E.K., Tan, J., Swank, R.T. Proc. Natl. Acad. Sci. U.S.A. (2005)
- Characterization of genes modulated during pheomelanogenesis using differential display. Furumura, M., Sakai, C., Potterf, S.B., Vieira, W.D., Barsh, G.S., Hearing, V.J. Proc. Natl. Acad. Sci. U.S.A. (1998)
- Involvement of ITF2 in the transcriptional regulation of melanogenic genes. Furumura, M., Potterf, S.B., Toyofuku, K., Matsunaga, J., Muller, J., Hearing, V.J. J. Biol. Chem. (2001)
- Catecholamine oxidative products, but not melanin, are produced by Cryptococcus neoformans during neuropathogenesis in mice. Liu, L., Wakamatsu, K., Ito, S., Williamson, P.R. Infect. Immun. (1999)
- UVA, pheomelanin and the carcinogenesis of melanoma. Hill, H.Z., Hill, G.J. Pigment Cell Res. (2000)
- Pheomelanin as a binding site for drugs and chemicals. Mårs, U., Larsson, B.S. Pigment Cell Res. (1999)
- Cyclic oscillations in melanin composition within hairs of baboons. Ito, S., Wakamatsu, K., Matsunaga, N., Hearing, V.J., Carey, K.D., Anderson, S., Dooley, T.P. Pigment Cell Res. (2001)
- Characterization of melanogenesis and morphogenesis of melanosomes by physicochemical properties of melanin and melanosomes in malignant melanoma. Jimbow, K., Miyake, Y., Homma, K., Yasuda, K., Izumi, Y., Tsutsumi, A., Ito, S. Cancer Res. (1984)
- Selective toxicity of 5-S-cysteinyldopa, a melanin precursor, to tumor cells in vitro and in vivo. Fujita, K., Ito, S., Inoue, S., Yamamoto, Y., Takeuchi, J., Shamoto, M., Nagatsu, T. Cancer Res. (1980)
- Modulation of melanogenic protein expression during the switch from eu- to pheomelanogenesis. Kobayashi, T., Vieira, W.D., Potterf, B., Sakai, C., Imokawa, G., Hearing, V.J. J. Cell. Sci. (1995)
- Pheomelanin production in the epidermis from newborn agouti mice is induced by the expression of the agouti gene in the dermis. Hirobe, T., Takeuchi, S., Hotta, E., Wakamatsu, K., Ito, S. Pigment Cell Res. (2004)
- Agouti alleles influence thiol concentrations in hair follicles and extrafollicular tissues of mice (Ay/a, AwJ/AwJ, a/a). Granholm, D.E., Reese, R.N., Granholm, N.H. Pigment Cell Res. (1995)
- Enhancement of pheomelanogenesis by L-dopa in the mouse melanocyte cell line, TM10, in vitro. Sato, C., Ito, S., Takeuchi, T. J. Cell. Sci. (1987)
- Stimulation of the proliferation and differentiation of mouse pink-eyed dilution epidermal melanocytes by excess tyrosine in serum-free primary culture. Hirobe, T., Wakamatsu, K., Ito, S., Abe, H., Kawa, Y., Mizoguchi, M. J. Cell. Physiol. (2002)
- Glutathione plays a key role in the depigmenting and melanocytotoxic action of N-acetyl-4-S-cysteaminylphenol in black and yellow hair follicles. Alena, F., Dixon, W., Thomas, P., Jimbow, K. J. Invest. Dermatol. (1995)
- Induction of melanization within hair bulb melanocytes in chinchilla mutant by melanogenic stimulants. Imokawa, G., Yada, Y., Hori, Y. J. Invest. Dermatol. (1988)
- The slaty mutation affects eumelanin and pheomelanin synthesis in mouse melanocytes. Hirobe, T., Wakamatsu, K., Ito, S., Kawa, Y., Soma, Y., Mizoguchi, M. Eur. J. Cell Biol. (2006)
- Interaction of major coat color gene functions in mice as studied by chemical analysis of eumelanin and pheomelanin. Lamoreux, M.L., Wakamatsu, K., Ito, S. Pigment Cell Res. (2001)
- The pinkeyed-dilution protein and the eumelanin/pheomelanin switch: in support of a unifying hypothesis. Lamoreux, M.L., Zhou, B.K., Rosemblat, S., Orlow, S.J. Pigment Cell Res. (1995)
- Melanin content of cultured human melanocytes and UV-induced cytotoxicity. De Leeuw, S.M., Smit, N.P., Van Veldhoven, M., Pennings, E.M., Pavel, S., Simons, J.W., Schothorst, A.A. J. Photochem. Photobiol. B, Biol. (2001)
- Quantitative trait loci that modify the sootiness of yellow pigmentation in KK-A(y)/a mice. Suto, J., Wakamatsu, K., Yamanaka, H., Ito, S., Sekikawa, K. Mamm. Genome (2000)
- A polymorphism in the agouti signaling protein gene is associated with human pigmentation. Kanetsky, P.A., Swoyer, J., Panossian, S., Holmes, R., Guerry, D., Rebbeck, T.R. Am. J. Hum. Genet. (2002)
- Effect of DOPA-loading on glutathione-dependent 5-S-cysteinyldopa genesis in melanoma cells in vitro. Mojamdar, M., Ichihashi, M., Mishima, Y. J. Invest. Dermatol. (1982)
- Glutathione reductase activity in skin exposed to 4-tertiary butyl catechol. Yonemoto, K., Gellin, G.A., Epstein, W.L., Fukuyama, K. International archives of occupational and environmental health. (1983)