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Gene Review

Eno2  -  enolase 2, gamma neuronal

Mus musculus

Synonyms: 2-phospho-D-glycerate hydro-lyase, AI837106, D6Ertd375e, Eno-2, Enolase 2, ...
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Disease relevance of Eno2


Psychiatry related information on Eno2

  • Neuronal degeneration was quantified by measuring the concentrations of microtubule associated protein tau and neuron specific enolase, which are also used as diagnostic tool in Alzheimer's disease, in supernatants [5].

High impact information on Eno2


Chemical compound and disease context of Eno2


Biological context of Eno2


Anatomical context of Eno2

  • The number of immunopositive cells in the NSE, NF, and synaptophysin staining within the infarct was progressively reduced, and after 3 to 7 days the immunoreactions were confined to discrete granulomatous structures in the center of the infarct, which otherwise was infested with macrophages [17].
  • TuJ1+ and nestin+ cells (neurons and stem cells, respectively) persist in the region into adulthood, although the numbers of these cells become more sparse as the animal develops, and they appear to be immature compared to the cells in surrounding forebrain structures (e.g., not expressing NSE and having few, if any, processes) [18].
  • The surviving inner hair cells vary in size, neuron-specific enolase content and innervation [19].
  • With regards to photoreceptors, NSE and SYN immunoreactive cones were seen in transplants from 14-16 weeks of age, but cone opsin immunoreactivity was not seen until 25 weeks [20].
  • A novel transgenic mouse line was generated to identify consequences on cortical development and function of expressing soluble NCAM-EC from the neuron-specific enolase promoter in the developing and mature neocortex and hippocampus [21].

Associations of Eno2 with chemical compounds


Regulatory relationships of Eno2


Other interactions of Eno2


Analytical, diagnostic and therapeutic context of Eno2


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