Gene Review:
Phox2a - paired-like homeobox 2a
Mus musculus
Synonyms:
Aristaless homeobox protein homolog, Arix, PHOX2A homeodomain protein, Paired mesoderm homeobox protein 2A, Paired-like homeobox 2A, ...
- Role of the target in the pathfinding of facial visceral motor axons. Jacob, J., Tiveron, M.C., Brunet, J.F., Guthrie, S. Mol. Cell. Neurosci. (2000)
- The SH2 domain containing inositol polyphosphate 5-phosphatase-2: SHIP2. Dyson, J.M., Kong, A.M., Wiradjaja, F., Astle, M.V., Gurung, R., Mitchell, C.A. Int. J. Biochem. Cell Biol. (2005)
- Phox2a gene, A6 neurons, and noradrenaline are essential for development of normal respiratory rhythm in mice. Viemari, J.C., Bévengut, M., Burnet, H., Coulon, P., Pequignot, J.M., Tiveron, M.C., Hilaire, G. J. Neurosci. (2004)
- Absence of the lipid phosphatase SHIP2 confers resistance to dietary obesity. Sleeman, M.W., Wortley, K.E., Lai, K.M., Gowen, L.C., Kintner, J., Kline, W.O., Garcia, K., Stitt, T.N., Yancopoulos, G.D., Wiegand, S.J., Glass, D.J. Nat. Med. (2005)
- The bHLH protein NEUROGENIN 2 is a determination factor for epibranchial placode-derived sensory neurons. Fode, C., Gradwohl, G., Morin, X., Dierich, A., LeMeur, M., Goridis, C., Guillemot, F. Neuron (1998)
- Defects in sensory and autonomic ganglia and absence of locus coeruleus in mice deficient for the homeobox gene Phox2a. Morin, X., Cremer, H., Hirsch, M.R., Kapur, R.P., Goridis, C., Brunet, J.F. Neuron (1997)
- Reciprocal gene replacements reveal unique functions for Phox2 genes during neural differentiation. Coppola, E., Pattyn, A., Guthrie, S.C., Goridis, C., Studer, M. EMBO J. (2005)
- Paired-like homeodomain proteins Phox2a/Arix and Phox2b/NBPhox have similar genetic organization and independently regulate dopamine beta-hydroxylase gene transcription. Adachi, M., Browne, D., Lewis, E.J. DNA Cell Biol. (2000)
- The cAMP pathway in combination with BMP2 regulates Phox2a transcription via cAMP response element binding sites. Benjanirut, C., Paris, M., Wang, W.H., Hong, S.J., Kim, K.S., Hullinger, R.L., Andrisani, O.M. J. Biol. Chem. (2006)
- Expression and interactions of the two closely related homeobox genes Phox2a and Phox2b during neurogenesis. Pattyn, A., Morin, X., Cremer, H., Goridis, C., Brunet, J.F. Development (1997)
- Specification of the central noradrenergic phenotype by the homeobox gene Phox2b. Pattyn, A., Goridis, C., Brunet, J.F. Mol. Cell. Neurosci. (2000)
- Expression of Ret-, p75(NTR)-, Phox2a-, Phox2b-, and tyrosine hydroxylase-immunoreactivity by undifferentiated neural crest-derived cells and different classes of enteric neurons in the embryonic mouse gut. Young, H.M., Ciampoli, D., Hsuan, J., Canty, A.J. Dev. Dyn. (1999)
- Ret deficiency in mice impairs the development of A5 and A6 neurons and the functional maturation of the respiratory rhythm. Viemari, J.C., Maussion, G., Bévengut, M., Burnet, H., Pequignot, J.M., Népote, V., Pachnis, V., Simonneau, M., Hilaire, G. Eur. J. Neurosci. (2005)
- Locus coeruleus neurons originate in alar rhombomere 1 and migrate into the basal plate: Studies in chick and mouse embryos. Aroca, P., Lorente-Cánovas, B., Mateos, F.R., Puelles, L. J. Comp. Neurol. (2006)
- Sp proteins and Phox2b regulate the expression of the human Phox2a gene. Flora, A., Lucchetti, H., Benfante, R., Goridis, C., Clementi, F., Fornasari, D. J. Neurosci. (2001)
- Eya1 and Six1 are essential for early steps of sensory neurogenesis in mammalian cranial placodes. Zou, D., Silvius, D., Fritzsch, B., Xu, P.X. Development (2004)
- Genetically modified bone morphogenetic protein signalling alters traumatic brain injury-induced gene expression responses in the adult mouse. Israelsson, C., Lewén, A., Kylberg, A., Usoskin, D., Althini, S., Lindeberg, J., Deng, C.X., Fukuda, T., Wang, Y., Kaartinen, V., Mishina, Y., Hillered, L., Ebendal, T. J. Neurosci. Res. (2006)