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Prlhr  -  prolactin releasing hormone receptor

Rattus norvegicus

Synonyms: G-protein coupled receptor 10, Gpr10, PrRP receptor, PrRPR, Prolactin-releasing peptide receptor, ...
 
 
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Disease relevance of Prlhr

  • We present here evidence that PrRP can modulate the activity of the reticular thalamic nucleus, a brain region with prominent PrRP receptor expression that is critical for sleep regulation and the formation of non-convulsive absence seizures [1].
 

High impact information on Prlhr

 

Biological context of Prlhr

 

Anatomical context of Prlhr

 

Analytical, diagnostic and therapeutic context of Prlhr

References

  1. Prolactin-releasing peptide (PrRP) promotes awakening and suppresses absence seizures. Lin, S.H., Arai, A.C., España, R.A., Berridge, C.W., Leslie, F.M., Huguenard, J.R., Vergnes, M., Civelli, O. Neuroscience (2002) [Pubmed]
  2. Prolactin-releasing peptide affects pain, allodynia and autonomic reflexes through medullary mechanisms. Kalliomäki, M.L., Pertovaara, A., Brandt, A., Wei, H., Pietilä, P., Kalmari, J., Xu, M., Kalso, E., Panula, P. Neuropharmacology (2004) [Pubmed]
  3. Expression of neuropeptide FF, prolactin-releasing peptide, and the receptor UHR1/GPR10 genes during embryogenesis in the rat. Nieminen, M.L., Nystedt, J., Panula, P. Dev. Dyn. (2003) [Pubmed]
  4. Characterization and distribution of prolactin releasing peptide (PrRP) binding sites in the rat--evidence for a novel binding site subtype in cardiac and skeletal muscle. Satoh, F., Smith, D.M., Gardiner, J.V., Mahmoodi, M., Murphy, K.G., Ghatei, M.A., Bloom, S.R. Br. J. Pharmacol. (2000) [Pubmed]
  5. Sequence and tissue distribution of a candidate G-coupled receptor cloned from rat hypothalamus. Welch, S.K., O'Hara, B.F., Kilduff, T.S., Heller, H.C. Biochem. Biophys. Res. Commun. (1995) [Pubmed]
  6. Morphological survey of prolactin-releasing peptide and its receptor with special reference to their functional roles in the brain. Ibata, Y., Iijima, N., Kataoka, Y., Kakihara, K., Tanaka, M., Hosoya, M., Hinuma, S. Neurosci. Res. (2000) [Pubmed]
  7. Tissue distribution of prolactin-releasing peptide (PrRP) and its receptor. Fujii, R., Fukusumi, S., Hosoya, M., Kawamata, Y., Habata, Y., Hinuma, S., Sekiguchi, M., Kitada, C., Kurokawa, T., Nishimura, O., Onda, H., Sumino, Y., Fujino, M. Regul. Pept. (1999) [Pubmed]
  8. Prolactin-releasing peptides do not stimulate prolactin release in vivo. Jarry, H., Heuer, H., Schomburg, L., Bauer, K. Neuroendocrinology (2000) [Pubmed]
  9. Expression of mammalian RF-amide peptides neuropeptide FF (NPFF), prolactin-releasing peptide (PrRP) and the PrRP receptor in the peripheral tissues of the rat. Nieminen, M.L., Brandt, A., Pietilä, P., Panula, P. Peptides (2000) [Pubmed]
  10. Neurochemical properties of the prolactin releasing peptide (PrRP) receptor expressing neurons: evidence for a role of PrRP as a regulator of stress and nociception. Lin, S.H., Leslie, F.M., Civelli, O. Brain Res. (2002) [Pubmed]
 
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