Gene Review:
HOXB6 - homeobox B6
Homo sapiens
Synonyms:
HOX2, HOX2B, HU-2, Homeobox protein Hox-2.2, Homeobox protein Hox-2B, ...
- HOXB6 protein is bound to CREB-binding protein and represses globin expression in a DNA binding-dependent, PBX interaction-independent process. Shen, W., Chrobak, D., Krishnan, K., Lawrence, H.J., Largman, C. J. Biol. Chem. (2004)
- Expression pattern of HOXB6 homeobox gene in myelomonocytic differentiation and acute myeloid leukemia. Giampaolo, A., Felli, N., Diverio, D., Morsilli, O., Samoggia, P., Breccia, M., Lo Coco, F., Peschle, C., Testa, U. Leukemia (2002)
- Changes in HOXB6 homeodomain protein structure and localization during human epidermal development and differentiation. Kömüves, L.G., Shen, W.F., Kwong, A., Stelnicki, E., Rozenfeld, S., Oda, Y., Blink, A., Krishnan, K., Lau, B., Mauro, T., Largman, C. Dev. Dyn. (2000)
- Deregulated expression of homeobox-containing genes, HOXB6, B8, C8, C9, and Cdx-1, in human colon cancer cell lines. Vider, B.Z., Zimber, A., Chastre, E., Gespach, C., Halperin, M., Mashiah, P., Yaniv, A., Gazit, A. Biochem. Biophys. Res. Commun. (2000)
- Genetic interaction between hoxb-5 and hoxb-6 is revealed by nonallelic noncomplementation. Rancourt, D.E., Tsuzuki, T., Capecchi, M.R. Genes Dev. (1995)
- Modulation of homeobox gene expression alters the phenotype of human hematopoietic cell lines. Shen, W.F., Detmer, K., Mathews, C.H., Hack, F.M., Morgan, D.A., Largman, C., Lawrence, H.J. EMBO J. (1992)
- Human homeo box-containing genes located at chromosome regions 2q31----2q37 and 12q12----12q13. Cannizzaro, L.A., Croce, C.M., Griffin, C.A., Simeone, A., Boncinelli, E., Huebner, K. Am. J. Hum. Genet. (1987)
- HOXB6 overexpression in murine bone marrow immortalizes a myelomonocytic precursor in vitro and causes hematopoietic stem cell expansion and acute myeloid leukemia in vivo. Fischbach, N.A., Rozenfeld, S., Shen, W., Fong, S., Chrobak, D., Ginzinger, D., Kogan, S.C., Radhakrishnan, A., Le Beau, M.M., Largman, C., Lawrence, H.J. Blood (2005)
- Evolution of the HOXB6 intergenic region: motif conservation at the lateral plate mesoderm (LPM) enhancer element. Deinard, A., Dorit, R., Castiglione, C., Jiang, Z., Becker, D., Ruddle, F., Schugart, K., Kidd, K. J. Exp. Zool. (1999)
- Alteration of homeobox gene expression by N-ras transformation of PA-1 human teratocarcinoma cells. Buettner, R., Yim, S.O., Hong, Y.S., Boncinelli, E., Tainsky, M.A. Mol. Cell. Biol. (1991)
- HOX genes in human lung: altered expression in primary pulmonary hypertension and emphysema. Golpon, H.A., Geraci, M.W., Moore, M.D., Miller, H.L., Miller, G.J., Tuder, R.M., Voelkel, N.F. Am. J. Pathol. (2001)
- HOXB13 homeodomain protein is cytoplasmic throughout fetal skin development. Kömüves, L.G., Ma, X.K., Stelnicki, E., Rozenfeld, S., Oda, Y., Largman, C. Dev. Dyn. (2003)
- Human colorectal carcinogenesis is associated with deregulation of homeobox gene expression. Vider, B.Z., Zimber, A., Hirsch, D., Estlein, D., Chastre, E., Prevot, S., Gespach, C., Yaniv, A., Gazit, A. Biochem. Biophys. Res. Commun. (1997)
- Differential expression of human HOX-2 genes along the anterior-posterior axis in embryonic central nervous system. Giampaolo, A., Acampora, D., Zappavigna, V., Pannese, M., D'Esposito, M., Carè, A., Faiella, A., Stornaiuolo, A., Russo, G., Simeone, A. Differentiation (1989)