Gene Review:
Cd2 - Cd2 molecule
Rattus norvegicus
Synonyms:
CD2R, LFA-2, LFA-3 receptor, LFA2, OX-34, ...
- T cell directed immunotherapy of inflammatory demyelination in the peripheral nervous system. Potent suppression of the effector phase of experimental autoimmune neuritis by anti-CD2 antibodies. Jung, S., Toyka, K., Hartung, H.P. Brain (1996)
- Suppression of experimental autoimmune encephalomyelitis in Lewis rats by antibodies against CD2. Jung, S., Toyka, K., Hartung, H.P. Eur. J. Immunol. (1995)
- Initiation and perpetuation of rat adjuvant arthritis is inhibited by the anti-CD2 monoclonal antibody (mAb) OX34. Hoffmann, J.C., Herklotz, C., Zeidler, H., Bayer, B., Rosenthal, H., Westermann, J. Ann. Rheum. Dis. (1997)
- Anti-CD2 monoclonal antibodies prevent the induction of experimental autoimmune myocarditis. Inomata, T., Watanabe, T., Haga, M., Hirahara, H., Abo, T., Okura, Y., Hanawa, H., Kodama, M., Izumi, T. Japanese heart journal. (2000)
- A role in transmembrane signaling for the cytoplasmic domain of the CD2 T lymphocyte surface antigen. He, Q., Beyers, A.D., Barclay, A.N., Williams, A.F. Cell (1988)
- Signal transduction by the CD2 antigen in T cells and natural killer cells: requirement for expression of a functional T cell receptor or binding of antibody Fc to the Fc receptor, Fc gamma RIIIA (CD16). Spruyt, L.L., Glennie, M.J., Beyers, A.D., Williams, A.F. J. Exp. Med. (1991)
- Inositol trisphosphate is generated by a rat natural killer cell tumor in response to target cells or to crosslinked monoclonal antibody OX-34: possible signaling role for the OX-34 determinant during activation by target cells. Seaman, W.E., Eriksson, E., Dobrow, R., Imboden, J.B. Proc. Natl. Acad. Sci. U.S.A. (1987)
- Coexistence of Th1- and Th2-type cytokine profiles in anti-CD2 monoclonal antibody-induced tolerance. Krieger, N.R., Most, D., Bromberg, J.S., Holm, B., Huie, P., Sibley, R.K., Dafoe, D.C., Alfrey, E.J. Transplantation (1996)
- Differential immunosuppressive activity of monoclonal CD2 antibodies on allograft rejection versus specific antibody production. Sido, B., Dengler, T.J., Otto, G., Zimmermann, R., Müller, P., Meuer, S.C. Eur. J. Immunol. (1998)
- Apoptosis of alpha beta T lymphocytes in the nervous system in experimental autoimmune encephalomyelitis: its possible implications for recovery and acquired tolerance. Pender, M.P., McCombe, P.A., Yoong, G., Nguyen, K.B. J. Autoimmun. (1992)
- CD2-SLFA3/T11TS interaction facilitates immune activation and glioma regression by apoptosis. Sarkar, S., Ghosh, A., Mukherjee, J., Chaudhuri, S., Chaudhuri, S. Cancer Biol. Ther. (2004)
- Structure of domain 1 of rat T lymphocyte CD2 antigen. Driscoll, P.C., Cyster, J.G., Campbell, I.D., Williams, A.F. Nature (1991)
- Antibody-dependent cellular cytotoxic activity of cells in the rat metrial gland in pregnancy. Peel, S., Stewart, I.J. Scand. J. Immunol. (1996)
- Organotin-induced thymus atrophy concerns the OX-44+ immature thymocytes. Relation to the interaction between early thymocytes and thymic epithelial cells? Pieters, R.H., Kampinga, J., Bol-Schoenmakers, M., Lam, B.W., Penninks, A.H., Seinen, W. Thymus (1989)
- Caffeine-dependent stimulus-triggered oscillations in the CA3 region of hippocampal slices from rats chronically exposed to lead. He, S.J., Xiao, C., Wu, Z.Y., Ruan, D.Y. Exp. Neurol. (2004)
- Effect of cadmium-induced lipid peroxidation on EEG spectral components. Ağar, A., Yargiçoğlu, P., Sentürk, U.K., Izgüt-Uysal, V.N. Journal of basic and clinical physiology and pharmacology. (1999)
- Anti-CD2 monoclonal antibodies prevent spontaneous and adoptive transfer of diabetes in the BB/Wor rat. Barlow, A.K., Like, A.A. Am. J. Pathol. (1992)
- Long-term survival of cardiac allografts in rats treated before and after surgery with monoclonal antibody to CD2. Hirahara, H., Tsuchida, M., Watanabe, T., Haga, M., Matsumoto, Y., Abo, T., Eguchi, S. Transplantation (1995)
- Anti-CD2 monoclonal antibody-induced receptor changes: down modulation of cell surface CD2. Lin, J., Yon, R.W., Chavin, K.D., Qin, L., Woodward, J., Ding, Y., Yagita, H., Bromberg, J.S. Transplantation (1995)