Gene Review:
TIE1 - tyrosine kinase with immunoglobulin-like...
Homo sapiens
Synonyms:
JTK14, TIE, Tyrosine-protein kinase receptor Tie-1
Dvorak,
Hess,
Hendrix,
Tognazzi,
Kirschmann,
Yancopoulos,
Meltzer,
Schatteman,
Brown,
Dezube,
Seftor,
Seftor,
Gardner,
- NERF2, a member of the Ets family of transcription factors, is increased in response to hypoxia and angiopoietin-1: a potential mechanism for Tie2 regulation during hypoxia. Christensen, R.A., Fujikawa, K., Madore, R., Oettgen, P., Varticovski, L. J. Cell. Biochem. (2002)
- Clinical relevance of Flt1 and Tie1 angiogenesis receptors expression in B-cell chronic lymphocytic leukemia (CLL). Aguayo, A., Manshouri, T., O'Brien, S., Keating, M., Beran, M., Koller, C., Kantarjian, H., Rogers, A., Albitar, M. Leuk. Res. (2001)
- Expression of Tie1, Tie2, and angiopoietins 1, 2, and 4 in Kaposi's sarcoma and cutaneous angiosarcoma. Brown, L.F., Dezube, B.J., Tognazzi, K., Dvorak, H.F., Yancopoulos, G.D. Am. J. Pathol. (2000)
- Expression and functional significance of VE-cadherin in aggressive human melanoma cells: role in vasculogenic mimicry. Hendrix, M.J., Seftor, E.A., Meltzer, P.S., Gardner, L.M., Hess, A.R., Kirschmann, D.A., Schatteman, G.C., Seftor, R.E. Proc. Natl. Acad. Sci. U.S.A. (2001)
- Multiple angiopoietin recombinant proteins activate the Tie1 receptor tyrosine kinase and promote its interaction with Tie2. Saharinen, P., Kerkelä, K., Ekman, N., Marron, M., Brindle, N., Lee, G.M., Augustin, H., Koh, G.Y., Alitalo, K. J. Cell Biol. (2005)
- Distinct rat genes with related profiles of expression define a TIE receptor tyrosine kinase family. Maisonpierre, P.C., Goldfarb, M., Yancopoulos, G.D., Gao, G. Oncogene (1993)
- Differential expression of the angiogenic Tie receptor family in arthritic and normal synovial tissue. Shahrara, S., Volin, M.V., Connors, M.A., Haines, G.K., Koch, A.E. Arthritis Res. (2002)
- Identification of receptor genes in renal cell carcinoma associated with angiogenesis by differential hybridization technique. Takahashi, A., Sasaki, H., Kim, S.J., Kakizoe, T., Miyao, N., Sugimura, T., Terada, M., Tsukamoto, T. Biochem. Biophys. Res. Commun. (1999)
- Expression of tie1 and tie2 proteins during reendothelialization in balloon-injured rat carotid artery. Fujikawa, K., Presman, E., Isner, J.M., Varticovski, L. J. Vasc. Res. (1999)
- Growth factor signaling pathways in vascular development. Tallquist, M.D., Soriano, P., Klinghoffer, R.A. Oncogene (1999)
- Regulated proteolytic processing of Tie1 modulates ligand responsiveness of the receptor-tyrosine kinase Tie2. Marron, M.B., Singh, H., Tahir, T.A., Kavumkal, J., Kim, H.Z., Koh, G.Y., Brindle, N.P. J. Biol. Chem. (2007)
- High expression of several tyrosine kinases and activation of the PI3K/AKT pathway in mediastinal large B cell lymphoma reveals further similarities to Hodgkin lymphoma. Renné, C., Willenbrock, K., Martin-Subero, J.I., Hinsch, N., Döring, C., Tiacci, E., Klapper, W., Möller, P., Küppers, R., Hansmann, M.L., Siebert, R., Bräuninger, A. Leukemia (2007)
- Cyclical mechanical stretch enhances angiopoietin-2 and Tie2 receptor expression in cultured human umbilical vein endothelial cells. Chang, H., Wang, B.W., Kuan, P., Shyu, K.G. Clin. Sci. (2003)
- The antiinflammatory endothelial tyrosine kinase Tie2 interacts with a novel nuclear factor-kappaB inhibitor ABIN-2. Hughes, D.P., Marron, M.B., Brindle, N.P. Circ. Res. (2003)
- Interaction between Tie receptors modulates angiogenic activity of angiopoietin2 in endothelial progenitor cells. Kim, K.L., Shin, I.S., Kim, J.M., Choi, J.H., Byun, J., Jeon, E.S., Suh, W., Kim, D.K. Cardiovasc. Res. (2006)
- Autocrine/paracrine role of the angiopoietin-1 and -2/Tie2 system in cell proliferation and chemotaxis of cultured fibroblastic synoviocytes in rheumatoid arthritis. Takahara, K., Iioka, T., Furukawa, K., Uchida, T., Nakashima, M., Tsukazaki, T., Shindo, H. Hum. Pathol. (2004)