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Gene Review

Fdps  -  farnesyl diphosphate synthase

Rattus norvegicus

Synonyms: (2E,6E)-farnesyl diphosphate synthase, Ac2-125, CR 39, Cholesterol-regulated 39 kDa protein, Dimethylallyltranstransferase, ...
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Disease relevance of Fdps

  • Delayed type hypersensitivity (DTH) is reported as percentage of hind-limb foot pad swelling (%FPS) [1].

High impact information on Fdps


Biological context of Fdps


Anatomical context of Fdps


Associations of Fdps with chemical compounds


Other interactions of Fdps


Analytical, diagnostic and therapeutic context of Fdps


  1. Perioperative growth hormone improves wound healing and immunologic function in rats receiving adriamycin. Harrison, L.E., Port, J.L., Hochwald, S., Blumberg, D., Burt, M. J. Surg. Res. (1995) [Pubmed]
  2. Testis-specific transcription initiation sites of rat farnesyl pyrophosphate synthetase mRNA. Teruya, J.H., Kutsunai, S.Y., Spear, D.H., Edwards, P.A., Clarke, C.F. Mol. Cell. Biol. (1990) [Pubmed]
  3. Molecular cloning and sequence of a cholesterol-repressible enzyme related to prenyltransferase in the isoprene biosynthetic pathway. Clarke, C.F., Tanaka, R.D., Svenson, K., Wamsley, M., Fogelman, A.M., Edwards, P.A. Mol. Cell. Biol. (1987) [Pubmed]
  4. Elucidation of the deficiency in two yeast coenzyme Q mutants. Characterization of the structural gene encoding hexaprenyl pyrophosphate synthetase. Ashby, M.N., Edwards, P.A. J. Biol. Chem. (1990) [Pubmed]
  5. Testis-specific transcripts of rat farnesyl pyrophosphate synthetase are developmentally regulated and localized to haploid germ cells. Teruya, J.H., Salido, E.C., Edwards, P.A., Clarke, C.F. Biol. Reprod. (1991) [Pubmed]
  6. Dispersed family of human genes with sequence similarity to farnesyl pyrophosphate synthetase. Heinzmann, C., Clarke, C.F., Klisak, I., Mohandas, T., Sparkes, R.S., Edwards, P.A., Lusis, A.J. Genomics (1989) [Pubmed]
  7. Feedback regulation of hepatic 3-hydroxy-3-methylglutaryl-CoA reductase activity by dietary cholesterol is not due to altered mRNA levels. Ness, G.C., Keller, R.K., Pendleton, L.C. J. Biol. Chem. (1991) [Pubmed]
  8. Pituitary regulation of the expression of the farnesyl pyrophosphate synthetase gene in the testes of the sexually maturing rat. Nazian, S.J., Brewer, L.D., Ness, G.C. J. Androl. (1991) [Pubmed]
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