Gene Review:
Ikbkb - inhibitor of kappa light polypeptide gene...
Rattus norvegicus
Synonyms:
AIM-1, I-kappa-B kinase 2, I-kappa-B-kinase beta, IKK-B, IKK-beta, ...
- Amelioration of arthritis by intraarticular dominant negative Ikk beta gene therapy using adeno-associated virus type 5. Tas, S.W., Adriaansen, J., Hajji, N., Bakker, A.C., Firestein, G.S., Vervoordeldonk, M.J., Tak, P.P. Hum. Gene Ther. (2006)
- Inhibitor of nuclear factor kappaB kinase beta is a key regulator of synovial inflammation. Tak, P.P., Gerlag, D.M., Aupperle, K.R., van de Geest, D.A., Overbeek, M., Bennett, B.L., Boyle, D.L., Manning, A.M., Firestein, G.S. Arthritis Rheum. (2001)
- Early activation of IKKbeta during in vivo myocardial ischemia. Li, C., Kao, R.L., Ha, T., Kelley, J., Browder, I.W., Williams, D.L. Am. J. Physiol. Heart Circ. Physiol. (2001)
- Enhancement of lipopolysaccharide-stimulated JNK activity in rat aortic smooth muscle cells by pharmacological and adenovirus-mediated inhibition of inhibitory kappa B kinase signalling. MacKenzie, C.J., Paul, A., Wilson, S., de Martin, R., Baker, A.H., Plevin, R. Br. J. Pharmacol. (2003)
- Activation of NF-kappa B is required for hypertrophic growth of primary rat neonatal ventricular cardiomyocytes. Purcell, N.H., Tang, G., Yu, C., Mercurio, F., DiDonato, J.A., Lin, A. Proc. Natl. Acad. Sci. U.S.A. (2001)
- Differential role of I kappa B kinase 1 and 2 in primary rat hepatocytes. Schwabe, R.F., Bennett, B.L., Manning, A.M., Brenner, D.A. Hepatology (2001)
- Peroxynitrite is a potent inhibitor of NF-{kappa}B activation triggered by inflammatory stimuli in cardiac and endothelial cell lines. Levrand, S., Pesse, B., Feihl, F., Waeber, B., Pacher, P., Rolli, J., Schaller, M.D., Liaudet, L. J. Biol. Chem. (2005)
- Nuclear factor kappa B-inducing kinase and Ikappa B kinase-alpha signal skeletal muscle cell differentiation. Canicio, J., Ruiz-Lozano, P., Carrasco, M., Palacin, M., Chien, K., Zorzano, A., Kaliman, P. J. Biol. Chem. (2001)
- Lipopolysaccharide improves cardiomyocyte survival and function after serum deprivation. Chao, W., Shen, Y., Zhu, X., Zhao, H., Novikov, M., Schmidt, U., Rosenzweig, A. J. Biol. Chem. (2005)
- Nuclear factor-kappaB represses hypoxia-induced mitochondrial defects and cell death of ventricular myocytes. Regula, K.M., Baetz, D., Kirshenbaum, L.A. Circulation (2004)
- A dominant negative form of IKK2 prevents suppression of apoptosis by the peroxisome proliferator nafenopin. Cosulich, S.C., James, N.H., Needham, M.R., Newham, P.P., Bundell, K.R., Roberts, R.A. Carcinogenesis (2000)
- Isorhapontigenin, a new resveratrol analog, attenuates cardiac hypertrophy via blocking signaling transduction pathways. Li, H.L., Wang, A.B., Huang, Y., Liu, D.P., Wei, C., Williams, G.M., Zhang, C.N., Liu, G., Liu, Y.Q., Hao, D.L., Hui, R.T., Lin, M., Liang, C.C. Free Radic. Biol. Med. (2005)
- Falcarindiol impairs the expression of inducible nitric oxide synthase by abrogating the activation of IKK and JAK in rat primary astrocytes. Shiao, Y.J., Lin, Y.L., Sun, Y.H., Chi, C.W., Chen, C.F., Wang, C.N. Br. J. Pharmacol. (2005)
- Inhibition of NF-kappaB induces regression of cardiac hypertrophy, independent of blood pressure control, in spontaneously hypertensive rats. Gupta, S., Young, D., Sen, S. Am. J. Physiol. Heart Circ. Physiol. (2005)
- HMG-CoA reductase inhibitors reduce I kappa B kinase activity induced by oxidative stress in monocytes and vascular smooth muscle cells. Ortego, M., Gómez-Hernández, A., Vidal, C., Sánchez-Galán, E., Blanco-Colio, L.M., Martín-Ventura, J.L., Tuñón, J., Diaz, C., Hernández, G., Egido, J. J. Cardiovasc. Pharmacol. (2005)
- IkappaB kinase-2-independent and -dependent inflammation in airway disease models: relevance of IKK-2 inhibition to the clinic. Birrell, M.A., Wong, S., Hardaker, E.L., Catley, M.C., McCluskie, K., Collins, M., Haj-Yahia, S., Belvisi, M.G. Mol. Pharmacol. (2006)