Gene Review:
IME2 - Ime2p
Saccharomyces cerevisiae S288c
Synonyms:
J0817, Meiosis induction protein kinase IME2/SME1, SME1, YJL106W
- Purification and some properties of Saccharomyces cerevisiae meiosis-specific protein kinase Ime2. Hui, C.M., Campistrous, A., Stuart, D.T. Protein Expr. Purif. (2002)
- Regulation of meiotic S phase by Ime2 and a Clb5,6-associated kinase in Saccharomyces cerevisiae. Dirick, L., Goetsch, L., Ammerer, G., Byers, B. Science (1998)
- Control of landmark events in meiosis by the CDK Cdc28 and the meiosis-specific kinase Ime2. Benjamin, K.R., Zhang, C., Shokat, K.M., Herskowitz, I. Genes Dev. (2003)
- GCN5-dependent histone H3 acetylation and RPD3-dependent histone H4 deacetylation have distinct, opposing effects on IME2 transcription, during meiosis and during vegetative growth, in budding yeast. Burgess, S.M., Ajimura, M., Kleckner, N. Proc. Natl. Acad. Sci. U.S.A. (1999)
- Inhibition of APC-mediated proteolysis by the meiosis-specific protein kinase Ime2. Bolte, M., Steigemann, P., Braus, G.H., Irniger, S. Proc. Natl. Acad. Sci. U.S.A. (2002)
- Glucose inhibits meiotic DNA replication through SCFGrr1p-dependent destruction of Ime2p kinase. Purnapatre, K., Gray, M., Piccirillo, S., Honigberg, S.M. Mol. Cell. Biol. (2005)
- Bipartite structure of an early meiotic upstream activation sequence from Saccharomyces cerevisiae. Bowdish, K.S., Mitchell, A.P. Mol. Cell. Biol. (1993)
- Tlk, a novel evolutionarily conserved murine serine threonine kinase, encodes multiple testis transcripts. Shalom, S., Don, J. Mol. Reprod. Dev. (1999)
- The Cdk-activating kinase Cak1p promotes meiotic S phase through Ime2p. Schindler, K., Benjamin, K.R., Martin, A., Boglioli, A., Herskowitz, I., Winter, E. Mol. Cell. Biol. (2003)
- Ime2, a meiosis-specific kinase in yeast, is required for destabilization of its transcriptional activator, Ime1. Guttmann-Raviv, N., Martin, S., Kassir, Y. Mol. Cell. Biol. (2002)
- The yeast trimeric guanine nucleotide-binding protein alpha subunit, Gpa2p, controls the meiosis-specific kinase Ime2p activity in response to nutrients. Donzeau, M., Bandlow, W. Mol. Cell. Biol. (1999)
- Arg-Pro-X-Ser/Thr Is a Consensus Phosphoacceptor Sequence for the Meiosis-Specific Ime2 Protein Kinase in Saccharomyces cerevisiae. Moore, M., Shin, M.E., Bruning, A., Schindler, K., Vershon, A., Winter, E. Biochemistry (2007)
- Purification and characterization of the DNA binding domain of Saccharomyces cerevisiae meiosis-specific transcription factor Ndt80. Sopko, R., Stuart, D.T. Protein Expr. Purif. (2004)
- Saccharomyces cerevisiae Ime2 phosphorylates Sic1 at multiple PXS/T sites but is insufficient to trigger Sic1 degradation. Sedgwick, C., Rawluk, M., Decesare, J., Raithatha, S., Wohlschlegel, J., Semchuk, P., Ellison, M., Yates, J., Stuart, D. Biochem. J. (2006)
- Regulation of the premiddle and middle phases of expression of the NDT80 gene during sporulation of Saccharomyces cerevisiae. Pak, J., Segall, J. Mol. Cell. Biol. (2002)
- Dual-specificity protein phosphatase Yvh1p, which is required for vegetative growth and sporulation, interacts with yeast pescadillo homolog in Saccharomyces cerevisiae. Sakumoto, N., Yamashita, H., Mukai, Y., Kaneko, Y., Harashima, S. Biochem. Biophys. Res. Commun. (2001)
- A transcriptional cascade governs entry into meiosis in Saccharomyces cerevisiae. Smith, H.E., Mitchell, A.P. Mol. Cell. Biol. (1989)
- Snf1 kinase connects nutritional pathways controlling meiosis in Saccharomyces cerevisiae. Honigberg, S.M., Lee, R.H. Mol. Cell. Biol. (1998)
- Evolution of Ime2 phosphorylation sites on Cdk1 substrates provides a mechanism to limit the effects of the phosphatase Cdc14 in meiosis. Holt, L.J., Hutti, J.E., Cantley, L.C., Morgan, D.O. Mol. Cell (2007)
- Genetic and molecular analysis of REC114, an early meiotic recombination gene in yeast. Pittman, D., Lu, W., Malone, R.E. Curr. Genet. (1993)
- Protein kinase activity associated with the IME2 gene product, a meiotic inducer in the yeast Saccharomyces cerevisiae. Kominami, K., Sakata, Y., Sakai, M., Yamashita, I. Biosci. Biotechnol. Biochem. (1993)