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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review


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Disease relevance of Agriculture


High impact information on Agriculture

  • Knowledge of metabolite dynamics is crucial to developing useful assays for monitoring atrazine exposure in agricultural workers [4].
  • Some agricultural workers using glyphosate have pregnancy problems, but its mechanism of action in mammals is questioned [5].
  • The hormonal disruption in agricultural workers presented here, together with results from experimental animal studies, suggests that OP exposure disrupts the hypothalamic-pituitary endocrine function and also indicates that FSH and LH are the hormones most affected [6].
  • The levels of AZM in migrant farmworker homes were most associated with the distance from fields and the number of agricultural workers in the home [7].
  • We have recently found in agricultural workers occupationally exposed to the fungicide mancozeb a statistically significant decrease in lipopolysaccharide (LPS)-induced tumor necrosis factor-alpha (TNF) production in leukocytes [8].

Biological context of Agriculture


Anatomical context of Agriculture


Associations of Agriculture with chemical compounds


Gene context of Agriculture

  • Both serum cholinesterase and PON1 activities were measured spectrophotometrically from 18 male agricultural workers who were chronically exposed to azinphos methyl, chlorpyriphos, or malathion and other pesticides during cereal spraying, transportation, and storage [17].
  • Comparison of food constituents in the diet of female agricultural workers in Japan with high and low concentrations of high density lipoprotein in their sera [18].
  • Limb reduction defects, however, occurred more frequently among offspring of agricultural workers (5.05 per 1 000 total births versus 2.19 per 1 000 total births, rate ratio = 2.3) [19].
  • A co-operative study by representatives of eight member countries of the EEC into the problem of respiratory disease among agricultural workers is reported [20].
  • ALS distribution in the study area was uniform but its occurrence was significantly higher among agricultural workers (5.28/100,000) [21].

Analytical, diagnostic and therapeutic context of Agriculture


  1. Sustained-release diltiazem in patients with effort angina and severe coronary artery sclerosis. Mizuki, T., Nakashima, Y., Segawa, K., Kuroiwa, A. Clinical therapeutics. (1990) [Pubmed]
  2. Cancer mortality among rice growers in Novara Province, northern Italy. Gambini, G.F., Mantovani, C., Pira, E., Piolatto, P.G., Negri, E. Am. J. Ind. Med. (1997) [Pubmed]
  3. First experience with ELISA serosurvey for tick-borne borreliosis (Lyme disease) in Czechoslovakia. Jirous, J., Pokorný, J., Zástĕra, M., Doutlík, S., Bojar, M. Journal of hygiene, epidemiology, microbiology, and immunology. (1988) [Pubmed]
  4. HPLC-accelerator MS measurement of atrazine metabolites in human urine after dermal exposure. Buchholz, B.A., Fultz, E., Haack, K.W., Vogel, J.S., Gilman, S.D., Gee, S.J., Hammock, B.D., Hui, X., Wester, R.C., Maibach, H.I. Anal. Chem. (1999) [Pubmed]
  5. Differential effects of glyphosate and roundup on human placental cells and aromatase. Richard, S., Moslemi, S., Sipahutar, H., Benachour, N., Seralini, G.E. Environ. Health Perspect. (2005) [Pubmed]
  6. Pesticide exposure alters follicle-stimulating hormone levels in Mexican agricultural workers. Recio, R., Ocampo-Gómez, G., Morán-Martínez, J., Borja-Aburto, V., López-Cervante, M., Uribe, M., Torres-Sánchez, L., Cebrián, M.E. Environ. Health Perspect. (2005) [Pubmed]
  7. Work characteristics and pesticide exposures among migrant agricultural families: a community-based research approach. McCauley, L.A., Lasarev, M.R., Higgins, G., Rothlein, J., Muniz, J., Ebbert, C., Phillips, J. Environ. Health Perspect. (2001) [Pubmed]
  8. Molecular mechanisms underlying mancozeb-induced inhibition of TNF-alpha production. Corsini, E., Viviani, B., Birindelli, S., Gilardi, F., Torri, A., Codecà, I., Lucchi, L., Bartesaghi, S., Galli, C.L., Marinovich, M., Colosio, C. Toxicol. Appl. Pharmacol. (2006) [Pubmed]
  9. Gas chromatographic-tandem mass spectrometric analytical method for the study of inhalation, potential dermal and actual exposure of agricultural workers to the pesticide malathion. Cruz Márquez, M., Arrebola, F.J., Egea González, F.J., Castro Cano, M.L., Martínez Vidal, J.L. Journal of chromatography. A. (2001) [Pubmed]
  10. Spermatogenesis in agricultural workers exposed to dibromochloropropane (DBCP). Sandifer, S.H., Wilkins, R.T., Loadholt, C.B., Lane, L.G., Eldridge, J.C. Bulletin of environmental contamination and toxicology. (1979) [Pubmed]
  11. Biological monitoring of agricultural workers exposed to pesticides: II. Monitoring of intact pesticides and their metabolites. Coye, M.J., Lowe, J.A., Maddy, K.J. Journal of occupational medicine. : official publication of the Industrial Medical Association. (1986) [Pubmed]
  12. An observational study on neurobehavioural effects of acute oxydemeton-methyl (insecticide and acaricide) exposure in rats. Kansal, D.K., Chakrabarti, A. Indian J. Physiol. Pharmacol. (2000) [Pubmed]
  13. Determination of DDT and related compounds in blood samples from agricultural workers. Guardino, X., Serra, C., Obiols, J., Rosell, M.G., Berenguer, M.J., López, F., Brosa, J. Journal of chromatography. A. (1996) [Pubmed]
  14. Cancer mortality among agricultural workers from Serrana Region, state of Rio de Janeiro, Brazil. Meyer, A., Chrisman, J., Moreira, J.C., Koifman, S. Environmental research. (2003) [Pubmed]
  15. Photometric determination of human serum bromide levels--a convenient biomonitoring parameter for methyl bromide exposure. Müller, M., Reinhold, P., Lange, M., Zeise, M., Jürgens, U., Hallier, E. Toxicol. Lett. (1999) [Pubmed]
  16. Procedure for the determination of residues of (2,4-dichlorophenoxy)acetic acid in dermal exposure pads, hand rinses, urine, and perspiration from agricultural workers exposed to the herbicide. Sell, C.R., Maitlen, J.C. J. Agric. Food Chem. (1983) [Pubmed]
  17. Paraoxonase and acetylcholinesterase activities in humans exposed to organophosphorous compounds. Akgür, S.A., Oztürk, P., Sözmen, E.Y., Delen, Y., Tanyalçin, T., Ege, B. J. Toxicol. Environ. Health Part A (1999) [Pubmed]
  18. Comparison of food constituents in the diet of female agricultural workers in Japan with high and low concentrations of high density lipoprotein in their sera. Chiba, K., Miyasaka, M., Koizumi, A., Kumai, M., Watanabe, T., Ikeda, M. Journal of epidemiology and community health. (1985) [Pubmed]
  19. Parental occupation and birth outcome in an agricultural community. Schwartz, D.A., Newsum, L.A., Heifetz, R.M. Scandinavian journal of work, environment & health. (1986) [Pubmed]
  20. Respiratory disease Mortality in Agricultural workers in eight member countries of the European community. Heller, R.F., Kelson, M.C. International journal of epidemiology. (1982) [Pubmed]
  21. Studies on epidemiological, clinical, and etiological aspects of ALS disease in Sardinia, Southern Italy. Rosati, G., Pinna, L., Granieri, E., Aiello, I., Tola, R., Agnetti, V., Pirisi, A., de Bastiani, P. Acta neurologica Scandinavica. (1977) [Pubmed]
  22. Depression of sperm counts among agricultural workers exposed to dibromochloropropane and ethylene dibromide. Takahashi, W., Wong, L., Rogers, B.J., Hale, R.W. Bulletin of environmental contamination and toxicology. (1981) [Pubmed]
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