Chemical Compound Review:
Fumazone 1,2-dibromo-3-chloro-propane
Synonyms:
Nemabrom, Nemafume, Nemagone, Fumagon, Nemagon, ...
- Infertility in male pesticide workers. Whorton, D., Krauss, R.M., Marshall, S., Milby, T.H. Lancet (1977)
- Metabolic activation of 1,2-dibromo-3-chloropropane: evidence for the formation of reactive episulfonium ion intermediates. Pearson, P.G., Soderlund, E.J., Dybing, E., Nelson, S.D. Biochemistry (1990)
- Cytogenetic effects from exposure to mixed pesticides and the influence from genetic susceptibility. Au, W.W., Sierra-Torres, C.H., Cajas-Salazar, N., Shipp, B.K., Legator, M.S. Environ. Health Perspect. (1999)
- Metabolic activation of 1,2-dibromo-3-chloropropane to mutagenic metabolites: detection and mechanism of formation of (Z)- and (E)-2-chloro-3-(bromomethyl)oxirane. Pearson, P.G., Omichinski, J.G., Myers, T.G., Søderlund, E.J., Dybing, E., Nelson, S.D. Chem. Res. Toxicol. (1990)
- Breast cancer and pesticides in Hawaii: the need for further study. Allen, R.H., Gottlieb, M., Clute, E., Pongsiri, M.J., Sherman, J., Obrams, G.I. Environ. Health Perspect. (1997)
- The role of oxidative and conjugative pathways in the activation of 1,2-dibromo-3-chloropropane to DNA-damaging products in rat testicular cells. Omichinski, J.G., Brunborg, G., Holme, J.A., Søderlund, E.J., Nelson, S.D., Dybing, E. Mol. Pharmacol. (1988)
- The exaggerated prolactin response to thyrotropin-releasing hormone and metoclopramide in 1,2-dibromo-3-chloropropane-induced azoospermia. Leroith, D., Potashnik, G., Dunn, J., Spitz, I.M. J. Clin. Endocrinol. Metab. (1981)
- Different mechanisms are involved in DNA damage, bacterial mutagenicity and cytotoxicity induced by 1,2-dibromo-3-chloropropane in suspensions of rat liver cells. Holme, J.A., Søderlund, E.J., Brunborg, G., Omichinski, J.G., Bekkedal, K., Trygg, B., Nelson, S.D., Dybing, E. Carcinogenesis (1989)
- The effects of drugs on sperm. Drife, J.O. Drugs (1987)
- Mutagenicity of halogenated propanes and their methylated derivatives. Ratpan, F., Plaumann, H. Environ. Mol. Mutagen. (1988)
- Detection and mechanism of formation of the potent direct-acting mutagen 2-bromoacrolein from 1,2-dibromo-3-chloropropane. Omichinski, J.G., Soderlund, E.J., Dybing, E., Pearson, P.G., Nelson, S.D. Toxicol. Appl. Pharmacol. (1988)
- Synthesis and mutagenicity of selectively methylated analogs of tris(2,3-dibromopropyl)phosphate and 1,2-dibromo-3-chloropropane. Omichinski, J.G., Søderlund, E.J., Bausano, J.A., Dybing, E., Nelson, S.D. Mutagenesis (1987)
- Morphology of nasal-cavity tumours in rats after chronic inhalation of 1,2-dibromo-3-chloropropane. Reznik, G., Reznik-Schüller, H., Ward, J.M., Stinson, S.F. Br. J. Cancer (1980)
- Problems associated with collecting drinking water quality data for community studies: a case example, Fresno County, California. Whorton, M.D., Morgan, R.W., Wong, O., Larson, S., Gordon, N. American journal of public health. (1988)
- Restoration of spermatogenesis in dibromochloropropane (DBCP)-treated rats by hormone suppression. Meistrich, M.L., Wilson, G., Porter, K.L., Huhtaniemi, I., Shetty, G., Shuttlesworth, G.A. Toxicol. Sci. (2003)
- Toxicokinetics of 1,2-dibromo-3-chloropropane (DBCP) in the rat. Gingell, R., Beatty, P.W., Mitschke, H.R., Page, A.C., Sawin, V.L., Putcha, L., Kramer, W.G. Toxicol. Appl. Pharmacol. (1987)
- A biochemical basis for 1,2-dibromo-3-chloropropane-induced male infertility: inhibition of sperm mitochondrial electron transport activity. Greenwell, A., Tomaszewski, K.E., Melnick, R.L. Toxicol. Appl. Pharmacol. (1987)
- Glutathione-mediated binding of dibromoalkanes to DNA: specificity of rat glutathione-S-transferases and dibromoalkane structure. Inskeep, P.B., Guengerich, F.P. Carcinogenesis (1984)
- 1,2-dibromo-3-chloropropane (DBCP)-induced infertility in male rats mediated by a post-testicular effect. Kluwe, W.M., Lamb, J.C., Greenwell, A.E., Harrington, F.W. Toxicol. Appl. Pharmacol. (1983)
- Effect of pesticides on testicular function. Marshall, S., Whorton, D., Krauss, R.M., Palmer, W.S. Urology (1978)
- Micronucleus induction by azobenzene and 1,2-dibromo-3-chloropropane in the rat: evaluation of a triple-dose protocol. George, E., Wootton, A.K., Gatehouse, D.G. Mutat. Res. (1990)
- Utilization of trihalogenated propanes by Agrobacterium radiobacter AD1 through heterologous expression of the haloalkane dehalogenase from Rhodococcus sp. strain M15-3. Bosma, T., Kruizinga, E., de Bruin, E.J., Poelarends, G.J., Janssen, D.B. Appl. Environ. Microbiol. (1999)
- Activation and inactivation of carcinogenic dihaloalkanes and other compounds by glutathione S-transferase 5-5 in Salmonella typhimurium tester strain NM5004. Shimada, T., Yamazaki, H., Oda, Y., Hiratsuka, A., Watabe, T., Guengerich, F.P. Chem. Res. Toxicol. (1996)
- Prevention of 1,2-dibromo-3-chloropropane (DBCP)-induced kidney necrosis and testicular atrophy by 3-aminobenzamide. Holme, J.A., Søderlund, J., Låg, M., Brunborg, G., Dybing, E. Toxicol. Appl. Pharmacol. (1991)
- Gonadotoxic effects of 2-hexanone and 1,2-dibromo-3-chloropropane on the enzymatic activity of rat testicular 17 alpha-hydroxylase/C17,20-lyase. Kelce, W.R., Raisbeck, M.F., Ganjam, V.K. Toxicol. Lett. (1990)
- Induction of aryl hydrocarbon hydroxylase and epoxide hydrolase in rat liver, kidney, testis, prostate glands, and stomach by a potent nematocide, 1,2-dibromo-3-chloropropane. Suzuki, K., Lee, I.P. Toxicol. Appl. Pharmacol. (1981)
- Dibromochloropropane inhibits spermatogonial development in rats. Meistrich, M.L., Wilson, G., Shuttlesworth, G.A., Porter, K.L. Reprod. Toxicol. (2003)
- Re "sperm count depression in pesticide applicators exposed to dibromochloropropane". Kahn, E., Whorton, D. Am. J. Epidemiol. (1980)
- Mouse specific-locus test for the induction of heritable gene mutations by dibromochloropropane (DBCP). Russell, L.B., Hunsicker, P.R., Cacheiro, N.L. Mutat. Res. (1986)
- Quantitative determination of 1,2-dibromo-3-chloropropane in whole rat blood and drinking water by gas chromatography. Kastl, P.E., Hermann, E.A., Braun, W.H. J. Chromatogr. (1981)
- Testicular necrosis and DNA damage caused by deuterated and methylated analogs of 1,2-dibromo-3-chloropropane in the rat. Søderlund, E.J., Brunborg, G., Omichinski, J.G., Holme, J.A., Dahl, J.E., Nelson, S.D., Dybing, E. Toxicol. Appl. Pharmacol. (1988)
- Effects of partial hepatectomy on organ-specific toxic response to 1,2-dibromo-3-chloropropane (DBCP). Kluwe, W.M. Journal of applied toxicology : JAT. (1983)