The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Reflex, Monosynaptic

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Reflex, Monosynaptic


High impact information on Reflex, Monosynaptic

  • The effects of neurotrophin-3 (NT-3) and NT-4/5 on the function of axotomized group Ia afferents and motoneurons comprising the monosynaptic reflex pathway were investigated [2].
  • This monosynaptic reflex was chosen because of its simple and well-defined circuitry, and because its motor component receives a dense NE innervation [3].
  • The role of capsaicin-sensitive muscle afferents in fatigue-induced modulation of the monosynaptic reflex in the rat [4].
  • Morphine (0.01-3 microM) and clonidine (0.03-1 microM) inhibited CAP-stimulated activity, but not the non-nociceptive dorsal root-evoked monosynaptic reflex (MSR) or polysynaptic (PSR) activity [5].
  • The AMPA/KA receptor antagonists CNQX (0.1-100 microM) and DNQX (0.1-30 microM) blocked nociceptive activity and were 4-fold selective for CAP-evoked potentials compared to the monosynaptic reflex [5].

Biological context of Reflex, Monosynaptic


Anatomical context of Reflex, Monosynaptic


Associations of Reflex, Monosynaptic with chemical compounds


Gene context of Reflex, Monosynaptic


  1. Effect of magnesium on depression of the monosynaptic reflex induced by 2-chloroadenosine or hypoxia in the isolated spinal cord of neonatal rats. Lloyd, H.G., Perkins, A., Spence, I. Neurosci. Lett. (1989) [Pubmed]
  2. Neurotrophin modulation of the monosynaptic reflex after peripheral nerve transection. Mendell, L.M., Johnson, R.D., Munson, J.B. J. Neurosci. (1999) [Pubmed]
  3. Noradrenergic modulation of the masseteric reflex in behaving cats. I. Pharmacological studies. Stafford, I.L., Jacobs, B.L. J. Neurosci. (1990) [Pubmed]
  4. The role of capsaicin-sensitive muscle afferents in fatigue-induced modulation of the monosynaptic reflex in the rat. Pettorossi, V.E., Della Torre, G., Bortolami, R., Brunetti, O. J. Physiol. (Lond.) (1999) [Pubmed]
  5. Effects of excitatory amino acid receptor antagonists on a capsaicin-evoked nociceptive reflex: a comparison with morphine, clonidine and baclofen. Ault, B., Hildebrand, L.M. Pain (1993) [Pubmed]
  6. Structure-activity relationships of phenylethylamine analogs in their serotonergic depressant effects on the spinal monosynaptic reflex in rats. Ono, H., Hasebe, Y., Mori, T., Fukuda, H., Kohno, M., Ohta, S., Hirobe, M. J. Pharmacobio-dyn. (1989) [Pubmed]
  7. Serotonergic fibers induce a long-lasting inhibition of monosynaptic reflex in the neonatal rat spinal cord. Yomono, H.S., Suzuki, H., Yoshioka, K. Neuroscience (1992) [Pubmed]
  8. Ventral root depolarization and spinal reflex augmentation by a TRH analog in rat spinal cord. Ono, H., Fukuda, H. Neuropharmacology (1982) [Pubmed]
  9. Presynaptic activation of the spinal serotonergic system in the rat by phencyclidine in vitro. Ohno, Y., Warnick, J.E. J. Pharmacol. Exp. Ther. (1989) [Pubmed]
  10. Segmental reflexes mediated by joint afferent neurons in cat knee. Grigg, P., Harrigan, E.P., Fogarty, K.E. J. Neurophysiol. (1978) [Pubmed]
  11. Locus coeruleus control of spinal motor output. Fung, S.J., Manzoni, D., Chan, J.Y., Pompeiano, O., Barnes, C.D. Prog. Brain Res. (1991) [Pubmed]
  12. Protirelin (thyrotropin-releasing hormone) in amyotrophic lateral sclerosis. The role of androgens. Miller, S.C., Warnick, J.E. Arch. Neurol. (1989) [Pubmed]
  13. Non-serotonergic depression of spinal monosynaptic reflex transmission by 5-hydroxytryptophan. Hall, E.D. Neuropharmacology (1981) [Pubmed]
  14. Electrophysiological evidence for nicotinic and muscarinic modulation of spinal cord reflexes. Ibrahim, N.A., Goldstein, B.D. Neuropharmacology (1989) [Pubmed]
  15. The modulation of the monosynaptic reflex by substance P in the hemisected spinal cord preparation of the rat and gerbil. Lepre, M., Evans, R.H., Olpe, H.R., Brugger, F. Neuroscience (1993) [Pubmed]
  16. Phylogenesis and regulated expression of the RUNT domain transcription factors RUNX1 and RUNX3. Levanon, D., Glusman, G., Bettoun, D., Ben-Asher, E., Negreanu, V., Bernstein, Y., Harris-Cerruti, C., Brenner, O., Eilam, R., Lotem, J., Fainaru, O., Goldenberg, D., Pozner, A., Woolf, E., Xiao, C., Yarmus, M., Groner, Y. Blood Cells Mol. Dis. (2003) [Pubmed]
  17. Physiological and pharmacological characterization of the spinal tachykinin NK2 receptor. Lepre, M., Olpe, H.R., Evans, R.H., Brugger, F. Eur. J. Pharmacol. (1994) [Pubmed]
  18. Effects of TA-0910, an orally active TRH analog, on the spinal reflex in spinal rats. Kinoshita, K., Nagao, T., Ono, H. Neuropharmacology (1994) [Pubmed]
  19. Isoflurane and an alpha 2-adrenoceptor agonist suppress nociceptive neurotransmission in neonatal rat spinal cord. Savola, M.K., Woodley, S.J., Maze, M., Kendig, J.J. Anesthesiology (1991) [Pubmed]
  20. Stimulatory and inhibitory effects of serotonergic hallucinogens on spinal mono- and polysynaptic reflex pathways in the rat. Yamazaki, J., Ono, H., Nagao, T. Neuropharmacology (1992) [Pubmed]
WikiGenes - Universities