Chemical Compound Review:
Halofuginone 7-bromo-6-chloro-3-[3-[(3R)- 3-hydroxy-2...
Synonyms:
SureCN12996241, AC1L1XZM, C16H17BrClN3O3, LS-140372, AKOS015918193, ...
- Halofuginone to prevent and treat thioacetamide-induced liver fibrosis in rats. Bruck, R., Genina, O., Aeed, H., Alexiev, R., Nagler, A., Avni, Y., Pines, M. Hepatology (2001)
- Halofuginone: a potent inhibitor of critical steps in angiogenesis progression. Elkin, M., Miao, H.Q., Nagler, A., Aingorn, E., Reich, R., Hemo, I., Dou, H.L., Pines, M., Vlodavsky, I. FASEB J. (2000)
- Amelioration of radiation-induced fibrosis: inhibition of transforming growth factor-beta signaling by halofuginone. Xavier, S., Piek, E., Fujii, M., Javelaud, D., Mauviel, A., Flanders, K.C., Samuni, A.M., Felici, A., Reiss, M., Yarkoni, S., Sowers, A., Mitchell, J.B., Roberts, A.B., Russo, A. J. Biol. Chem. (2004)
- Inhibition of bladder carcinoma angiogenesis, stromal support, and tumor growth by halofuginone. Elkin, M., Ariel, I., Miao, H.Q., Nagler, A., Pines, M., de-Groot, N., Hochberg, A., Vlodavsky, I. Cancer Res. (1999)
- Reduction in pulmonary fibrosis in vivo by halofuginone. Nagler, A., Firman, N., Feferman, R., Cotev, S., Pines, M., Shoshan, S. Am. J. Respir. Crit. Care Med. (1996)
- The effect of halofuginone lactate on experimental Cryptosporidium parvum infections in calves. Naciri, M., Mancassola, R., Yvoré, P., Peeters, J.E. Vet. Parasitol. (1993)
- Screening for the coccidiostats halofuginone and nicarbazin in egg and chicken muscle: development of an ELISA. Huet, A.C., Mortier, L., Daeseleire, E., Fodey, T., Elliott, C., Delahaut, P. Food additives and contaminants. (2005)
- Prevalence and control of bovine cryptosporidiosis in German dairy herds. Joachim, A., Krull, T., Schwarzkopf, J., Daugschies, A. Vet. Parasitol. (2003)
- Field study of the efficacy of halofuginone and decoquinate in the treatment of cryptosporidiosis in veal calves. Lallemand, M., Villeneuve, A., Belda, J., Dubreuil, P. Vet. Rec. (2006)
- Halofuginone inhibition of COL1A2 promoter activity via a c-Jun-dependent mechanism. McGaha, T.L., Kodera, T., Spiera, H., Stan, A.C., Pines, M., Bona, C.A. Arthritis Rheum. (2002)
- Halofuginone, a collagen type I inhibitor improves liver regeneration in cirrhotic rats. Spira, G., Mawasi, N., Paizi, M., Anbinder, N., Genina, O., Alexiev, R., Pines, M. J. Hepatol. (2002)
- Halofuginone inhibits NF-kappaB and p38 MAPK in activated T cells. Leiba, M., Cahalon, L., Shimoni, A., Lider, O., Zanin-Zhorov, A., Hecht, I., Sela, U., Vlodavsky, I., Nagler, A. J. Leukoc. Biol. (2006)
- Inhibition of collagen synthesis, smooth muscle cell proliferation, and injury-induced intimal hyperplasia by halofuginone. Nagler, A., Miao, H.Q., Aingorn, H., Pines, M., Genina, O., Vlodavsky, I. Arterioscler. Thromb. Vasc. Biol. (1997)
- Efficacy of halofuginone lactate against Cryptosporidium parvum in calves. Villacorta, I., Peeters, J.E., Vanopdenbosch, E., Ares-Mazás, E., Theys, H. Antimicrob. Agents Chemother. (1991)
- Inhibition of glomerular mesangial cell proliferation and extracellular matrix deposition by halofuginone. Nagler, A., Katz, A., Aingorn, H., Miao, H.Q., Condiotti, R., Genina, O., Pines, M., Vlodavsky, I. Kidney Int. (1997)
- Discriminant analysis of antibiotic resistance patterns in fecal streptococci, a method to differentiate human and animal sources of fecal pollution in natural waters. Wiggins, B.A. Appl. Environ. Microbiol. (1996)
- Treatment with halofuginone results in marked growth inhibition of a von Hippel-Lindau pheochromocytoma in vivo. Gross, D.J., Reibstein, I., Weiss, L., Slavin, S., Dafni, H., Neeman, M., Pines, M., Nagler, A. Clin. Cancer Res. (2003)
- Smad3 as a mediator of the fibrotic response. Flanders, K.C. International journal of experimental pathology. (2004)