Disease relevance of Trismus

• Maxillofacial abnormalities comprised trismus, abnormal occlusal relationships, and facial deformities [1].
• Suxamethonium, masseter spasm and later malignant hyperthermia [2].
• The intravenous (i.v.) administration of succinylcholine (2.0 mg/kg) induced fasciculations and masseter spasm in both normal swine and those susceptible to MH [3].
• A 4-year-old boy with Williams syndrome developed masseter spasm after halothane and suxamethonium [4].
• Five indications were identified among these cases: 1) excessive emesis or hemorrhage (11), 2) possible cervical spine injury with airway compromise (9), 3) technical failure (7), 4) clenched teeth (5), and 5) masseter spasm following succinylcholine administration (1) [5].

High impact information on Trismus

• Recurrent trismus and stridor in an ALS patient: successful treatment with botulinum toxin [6].
• Facial swelling, trismus, serum C-reactive protein, serum cortisol, pain and anxiety were measured 24 h postoperatively [7].
• Skeletal and pigment cell defects in the lockjaw mutant reveal multiple roles for zebrafish tfap2a in neural crest development [8].
• Succinylcholine and trismus [9].
• Increased incidence of masseter spasm in children with strabismus anesthetized with halothane and succinylcholine [10].

Chemical compound and disease context of Trismus

• Implications of masseter spasm after succinylcholine [11].
• Masseter spasm after suxamethonium [12].
• Prolonged apnoea, trismus and ketamine [13].
• Masseter spasm after pancuronium [14].
• Fatal serotonin syndrome with trismus [15].

Anatomical context of Trismus

• Succinylcholine-triggered masseter spasm in a patient with trigeminal nerve palsy [16].
• OBJECTIVE: The aim of this study was to compare the effects of intravenous administration of 1.5 mg/kg and 3 mg/kg of methylprednisolone sodium succinate (MP) on pain, swelling, and trismus after third molar surgery [17].
• The clinical presentation of fever, trismus and odynophagia was consistent with pertonsillar abscess (PTA), but the presence of symmetric tonsillar swelling and midline uvula confounded the diagnosis [18].

Gene context of Trismus

• Trismus was evaluated as maximum interincisal distance (MID), determined before surgery and 1 and 5 days after surgery (MID0, MID1 and MID5 respectively) [19].
• Trismus as a presenting symptom in nasopharyngeal carcinoma [20].
• Masseter spasm occurred as sole sign in 21 families, of which 11 were MHS [21].
• Other factors of importance were: an increase in the anterior depth of the mandible; a reduction in the distance between the occiput and the spinous process of C1, and to a lesser extent the C1-C2 interspinous gap; and reduced mobility of the mandible associated with temporo-mandibular joint arthritis or trismus [22].
• Whilst blepharospasm--involuntary bilateral eye closure--is produced by spasmodic contractions of the orbicularis oculi muscles, oromandibular dystonia may cause jaw closure with trismus and bruxism, or involuntary jaw opening or deviation, interfering with speaking and chewing [23].

Analytical, diagnostic and therapeutic context of Trismus

• One patient developed marked trismus and one needed reoperation and trimming of the anchoring titanium plate on the malar process [24].
• Twenty-one days after IoN constriction, formalin injection provoked an immediate response that involved both directed grooming and other abnormal behaviors, e.g. flinching, trismus and shielding of the affected region [25].
• Relief of pain and trismus in patients treated with naproxen or acetylsalicylic acid after tonsillectomy [26].
• Twenty patients with severe trismus (dental gap < or = 25 mm) after receiving radiotherapy for nasopharyngeal carcinoma were enrolled onto the study [27].

References