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MeSH Review


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Disease relevance of Bruxism


Psychiatry related information on Bruxism


High impact information on Bruxism

  • Acute temporomandibular arthritis in a patient with bruxism and calcium pyrophosphate deposition disease [11].
  • The majority of gastroesophageal reflux episodes with a pH of 4.0 to 5.0 also included both an RMMA episode and an electromyographic burst in the control and bruxism groups (100% +/- 0.0% vs 70.7% +/- 16.5%), again probably due to swallowing of saliva [12].
  • Citalopram-induced bruxism [13].
  • Buspirone as an antidote to SSRI-induced bruxism in 4 cases [14].
  • BACKGROUND: One hypothesis to explain selective serotonin reuptake inhibitor (SSRI)-induced bruxism states that SSRIs increase extrapyramidal serotonin levels, thereby inhibiting dopaminergic pathways controlling movement [14].

Chemical compound and disease context of Bruxism

  • Can bruxism respond to serotonin reuptake inhibitors [15]?
  • CASE REPORTS: Four patients, recently started on treatment with the SSRI sertraline, presented with new-onset complaints attributable to SSRI-induced bruxism [14].
  • Occlusal disharmonies have classically been thought to be involved in the etiopathogenesis of bruxism, as have, more recently, alterations in central neurotransmission, particularly dopaminergic neurotransmission [16].
  • Activation of this latter structure may partly explain the bruxism (grinding of the jaw) reported by human 3,4-methylenedioxymethamphetamine users [17].
  • RESULTS: The search yielded complex information referring to the association between bruxism and dopamine-related drugs, antidepressant drugs, sedative and anxiolytic drugs, and drugs of abuse [1].

Biological context of Bruxism


Anatomical context of Bruxism


Gene context of Bruxism


Analytical, diagnostic and therapeutic context of Bruxism


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  2. Adverse response to methylphenidate in combination with valproic acid. Gara, L., Roberts, W. Journal of child and adolescent psychopharmacology. (2000) [Pubmed]
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  12. Association between nocturnal bruxism and gastroesophageal reflux. Miyawaki, S., Tanimoto, Y., Araki, Y., Katayama, A., Fujii, A., Takano-Yamamoto, T. Sleep. (2003) [Pubmed]
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  15. Can bruxism respond to serotonin reuptake inhibitors? Stein, D.J., Van Greunen, G., Niehaus, D. The Journal of clinical psychiatry. (1998) [Pubmed]
  16. Occlusal disharmonies modulate central catecholaminergic activity in the rat. Areso, M.P., Giralt, M.T., Sainz, B., Prieto, M., García-Vallejo, P., Gómez, F.M. J. Dent. Res. (1999) [Pubmed]
  17. The distribution of 3,4-methylenedioxymethamphetamine "Ecstasy"-induced c-fos expression in rat brain. Stephenson, C.P., Hunt, G.E., Topple, A.N., McGregor, I.S. Neuroscience (1999) [Pubmed]
  18. The relationship between bruxism and occlusal factors among seven- to 19-year-old Turkish children. Demir, A., Uysal, T., Guray, E., Basciftci, F.A. The Angle orthodontist. (2004) [Pubmed]
  19. Effect of occlusal wear on bone loss and Periotest value of dental implants. Engel, E., Gomez-Roman, G., Axmann-Krcmar, D. The International journal of prosthodontics. (2001) [Pubmed]
  20. Bruxism: its significance in coma. Pratap-Chand, R., Gourie-Devi, M. Clinical neurology and neurosurgery. (1985) [Pubmed]
  21. Bruxism secondary to antipsychotic drug exposure: a positive response to propranolol. Amir, I., Hermesh, H., Gavish, A. Clinical neuropharmacology. (1997) [Pubmed]
  22. Effect of occlusal splints on the EMG activity of masseter and temporal muscles in bruxism with clinical symptoms. Hamada, T., Kotani, H., Kawazoe, Y., Yamada, S. Journal of oral rehabilitation. (1982) [Pubmed]
  23. Tiagabine may reduce bruxism and associated temporomandibular joint pain. Kast, R.E. Anesthesia progress. (2005) [Pubmed]
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  25. Prevalence of bruxism in children receiving treatment for attention deficit hyperactivity disorder: a pilot study. Malki, G.A., Zawawi, K.H., Melis, M., Hughes, C.V. The Journal of clinical pediatric dentistry. (2004) [Pubmed]
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