Disease relevance of Tonsillectomy

• Although there are many papers about IgA nephropathy (IgAN) and tonsils, respectively, reviews about the relationship between tonsils, tonsillitis, tonsillectomy, and IgAN are limited [1].
• CONCLUSIONS: The intravenous administration of ondansetron 0.15 mg.kg-1 is highly effective in reducing postoperative emesis in children undergoing tonsillectomy [2].
• RESULTS: Contrary to the previous findings in ulcerative colitis, which were again confirmed in this study, appendectomy and/or tonsillectomy did not influence the occurrence of celiac disease [3].
• Pain relief after tonsillectomy. Effect of benzydamine hydrochloride spray on postoperative pain relief after tonsillectomy [4].
• Ondansetron decreases emesis after tonsillectomy in children [5].

Psychiatry related information on Tonsillectomy

• Since clinical variant CJD is uniformly associated with tonsillar prion infection, we screened 2000 anonymous surgical tonsillectomy specimens for disease-associated prion protein [6].

High impact information on Tonsillectomy

• In some patients with rheumatoid arthritis (RA), the disease improves following tonsillectomy [7].
• Expression of CYPs 1A1, 2E1, and 3A4 was quantified in tissue from 160 pediatric patients undergoing tonsillectomy [8].
• Relationship between tonsils and IgA nephropathy as well as indications of tonsillectomy [1].
• Scheduled dosing of acetaminophen with codeine did not provide adequate pain relief for children following tonsillectomy [9].
• RESULTS: Age, gender, amount of urinary protein excretion, serum creatinine, serum IgA, blood pressure, and histopathologic findings at the time of renal biopsy and treatments during the observation period were not significantly different between patients with and without tonsillectomy [10].

Chemical compound and disease context of Tonsillectomy

• CONCLUSIONS: In children undergoing tonsillectomy with or without adenoidectomy, reversal of neuromuscular blockade with atropine and neostigmine is associated with a lesser incidence of postoperative emesis compared with glycopyrrolate and neostigmine [11].
• In this study we determined the moxifloxacin concentrations in plasma and tonsillar tissue after the administration of three doses of moxifloxacin 400 mg to adult patients with chronic or recurrent tonsillitis undergoing tonsillectomy [12].
• The effect of dexamethasone on postoperative vomiting after tonsillectomy [13].
• Preoperative oral antiemetics for reducing postoperative vomiting after tonsillectomy in children: granisetron versus perphenazine [14].
• IMPLICATIONS: We compared the efficacy of granisetron and perphenazine given orally for preventing postoperative vomiting after tonsillectomy with or without adenoidectomy in children [14].

Biological context of Tonsillectomy

• The degree of hydrolysis of 2'-AE to erythromycin was about 25% in plasma at the time of tonsillectomy for both EA groups and about 40% in tonsillar tissue [15].
• Hemostasis during tonsillectomy was significantly more difficult to achieve in patients receiving ketorolac [16].
• Studies on the quantitative bacteriology of tonsils obtained at tonsillectomy have shown large numbers of both haemolytic streptococci and Haemophilus species in most samples and these organisms can be effectively reduced in number by preoperative treatment with antibiotics such as erythromycin [17].

Anatomical context of Tonsillectomy

• MATERIALS AND METHODS: Human lymphocytes were obtained by tonsillectomy and cultured in the presence of phytohaemagglutinin and elastin peptides [18].
• Pain relief and sputum prostaglandins in adults treated with pethidine, tilidine and indomethacin after tonsillectomy: a double-blind study [19].
• Silver nitrate was applied at predetermined contact times to tonsillar mucosa, immediately before tonsillectomy in subjects undergoing routine surgery [20].
• We report a case of a 4-year-old boy who developed peripheral facial nerve paralysis after perioperative infiltration of bupivacaine and uneventful tonsillectomy [21].
• The degree of mesangial cell proliferation, expansion of mesangial area and the number of PCNA positive cells were not changed after tonsillectomy [22].

Associations of Tonsillectomy with chemical compounds

• The efficacy of ketorolac, a non-steroidal anti-inflammatory drug, in the management of moderate to severe pain in adults, has led us to conduct a trial of this analgesic in children following tonsillectomy [23].
• Levels of roxithromycin in serum and tissue were investigated in 29 subjects undergoing tonsillectomy [24].
• All-night polysomnographic recordings and 24 hr measurements of plasma luteinizing hormone (LH) concentrations (sampling at 20 min intervals) were performed before and after combined tonsillectomy, adenoidectomy, and uvulectomy [25].
• Prophylactic antiemetic treatment with ondansetron in children undergoing tonsillectomy [2].
• Ondansetron or metoclopramide in children undergoing tonsillectomy [26].

Gene context of Tonsillectomy

• IL-8 production in PBMC was closely related to the clinical severity of psoriasis and to the response to treatment, including systemic methotrexate (MTX) treatment and tonsillectomy [27].
• Immunohistochemistry for alpha-smooth muscle actin (alpha-SMA), CD68 and proliferating cell nuclear antigen (PCNA) were performed and histological findings were compared before and after tonsillectomy [22].
• Tonsillar tissue was obtained from patients undergoing tonsillectomy and chemokine expression was investigated by means of immunohistochemistry [28].
• After tonsillectomy, IL-1beta and IL-6 levels were significantly reduced (p < 0.05) [29].
• Tonsillectomy and MRSA carriage [30].

Analytical, diagnostic and therapeutic context of Tonsillectomy

• MALTectomy (appendectomy/tonsillectomy) does not influence the occurrence or mode of presentation of adult celiac disease [3].
• I.v. ketoprofen for analgesia after tonsillectomy: comparison of pre- and post-operative administration [31].
• In a double blind study we compared the effects of i.m. ketamine with morphine on postoperative analgesia in children undergoing tonsillectomy [32].
• A double-blind trial was undertaken to compare the effects of trimeprazine tartrate (2 mg kg-1 or 4 mg kg-1) plus atropine 0.03 mg kg-1 for oral premedication of 192 children undergoing tonsillectomy [33].
• A comparison of oral clonidine and oral midazolam as preanesthetic medications in the pediatric tonsillectomy patient [34].

References