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MeSH Review

Cardiac Output, High

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Disease relevance of Cardiac Output, High


High impact information on Cardiac Output, High


Chemical compound and disease context of Cardiac Output, High

  • Eight of 10 hearts not receiving aspartate failed at high cardiac outputs [11].
  • In the first study, steady-state periods of low, medium, and high cardiac output were achieved by altering carbon dioxide tension in six halothane-anesthetized sheep [12].
  • Peak waveform velocities were measured during conditions of light anesthesia with isoflurane (baseline; period 1), cardiovascular depression following administration of high-dose isoflurane and esmolol i.v. (period 2), cardiovascular depression with crystalloid volume expansion (period 3), and high cardiac output induced with dobutamine (period 4) [13].
  • Acute fulminant cardiovascular beriberi is an acute thiamine deficiency, which, if not recognized and treated, can lead to high cardiac output failure and death [14].
  • To evaluate late pulmonary venous obstruction following surgical repair in patients with total anomalous pulmonary venous connection, which may be disclosed at high cardiac output but not at rest, a hemodynamic study was performed using isoproterenol infusion [15].

Biological context of Cardiac Output, High


Gene context of Cardiac Output, High

  • CONCLUSIONS: The administration of LCT emulsion given at a slow rate did not alter arterial oxygenation because of the beneficial effect of a high cardiac output, hence offsetting the detrimental effect of increased O2 consumption [20].
  • Renormalization of high cardiac output and of left ventricular size following long-term recombinant human erythropoietin treatment of anemic dialyzed uremic patients [21].
  • CONCLUSIONS: The correlation between cycling performance, LVM and SV suggests that the more conditioned athletes may be better able to maintain a high cardiac output during prolonged cycling [22].

Analytical, diagnostic and therapeutic context of Cardiac Output, High

  • The purpose of this study is to evaluate the hemodynamic performance of pulmonary autografts in the aortic position and the homografts used to reconstruct the right ventricular outflow tract during conditions of high cardiac output by means of dobutamine stress echocardiography [23].


  1. High-dose almitrine bismesylate inhibits hypoxic pulmonary vasoconstriction in closed-chest dogs. Chen, L., Miller, F.L., Malmkvist, G., Clergue, F.X., Marshall, C., Marshall, B.E. Anesthesiology (1987) [Pubmed]
  2. Bimodal cardiac dysfunction in an animal model of iron overload. Yang, T., Dong, W.Q., Kuryshev, Y.A., Obejero-Paz, C., Levy, M.N., Brittenham, G.M., Kiatchoosakun, S., Kirkpatrick, D., Hoit, B.D., Brown, A.M. J. Lab. Clin. Med. (2002) [Pubmed]
  3. The alcoholic cardiomyopathies--genuine and pseudo. Constant, J. Cardiology (1999) [Pubmed]
  4. Neonatal hemangiomatosis and atrial septal defect: a rare cause of right heart failure in infancy. Sidwell, R.U., Daubeney, P.E., Porter, W., Roberts, N.M. Pediatric dermatology. (2004) [Pubmed]
  5. Crow-Fukase syndrome associated with high-output heart failure. Araki, T., Konno, T., Soma, R., Nakashima, A., Takimoto, H., Tofuku, Y., Shimizu, M. Intern. Med. (2002) [Pubmed]
  6. The relationship between intrahepatic portal systemic shunts and microsphere induced portal hypertension in the rat liver. Li, X., Benjamin, I.S., Alexander, B. Gut (1998) [Pubmed]
  7. Abnormal glomerular response to atrial natriuretic peptide in rats with aortocaval fistulas. Norling, L.L., Thornhill, B.A., Chevalier, R.L. J. Am. Soc. Nephrol. (1996) [Pubmed]
  8. Atrial natriuretic peptide and hemodynamic changes during normal human pregnancy. Sala, C., Campise, M., Ambroso, G., Motta, T., Zanchetti, A., Morganti, A. Hypertension (1995) [Pubmed]
  9. Pulmonary hypertension complicating portal hypertension. A case report with suggestions for a different therapeutic approach. Boot, H., Visser, F.C., Thijs, J.C., Meuwissen, S.G. Eur. Heart J. (1987) [Pubmed]
  10. Intravenous PGF2 alpha infusion does not enhance hypoxic pulmonary vasoconstriction during canine one-lung hypoxia. Chen, L., Miller, F.L., Malmkvist, G., Cooley, R., Marshall, C., Marshall, B.E. Anesthesiology (1988) [Pubmed]
  11. Safety of prolonged aortic clamping with blood cardioplegia. III. Aspartate enrichment of glutamate-blood cardioplegia in energy-depleted hearts after ischemic and reperfusion injury. Rosenkranz, E.R., Okamoto, F., Buckberg, G.D., Robertson, J.M., Vinten-Johansen, J., Bugyi, H.I. J. Thorac. Cardiovasc. Surg. (1986) [Pubmed]
  12. Cardiac output is a determinant of the initial concentrations of propofol after short-infusion administration. Upton, R.N., Ludbrook, G.L., Grant, C., Martinez, A.M. Anesth. Analg. (1999) [Pubmed]
  13. Pulsed-wave Doppler ultrasonographic evaluation of hepatic veins during variable hemodynamic states in healthy anesthetized dogs. Smithenson, B.T., Mattoon, J.S., Bonagura, J.D., Abrahamsen, E.J., Drost, W.T. Am. J. Vet. Res. (2004) [Pubmed]
  14. Early recognition of acute cardiovascular beriberi by interpretation of hemodynamics. Gabrielli, A., Caruso, L., Stacpoole, P.W. Journal of clinical anesthesia. (2001) [Pubmed]
  15. Long-term results after surgical repair of total anomalous pulmonary venous connection--hemodynamic evaluation of pulmonary venous obstruction with isoproterenol infusion. Fujino, H., Nakazawa, M., Momma, K., Imai, Y. Jpn. Circ. J. (1995) [Pubmed]
  16. Oxygen utilization, carbon dioxide elimination and ventilation during recovery from supine bicycle exercise 6 to 8 weeks after acute myocardial infarction. Sumimoto, T., Sugiura, T., Takeuchi, M., Yuasa, F., Hasegawa, T., Nakamura, S., Iwasaka, T., Inada, M. Am. J. Cardiol. (1991) [Pubmed]
  17. Cardiovascular effects of exercise in hamsters with experimental thiamine deficiency. Hirota, Y., Kane, R.L., Abelmann, W.H. Jpn. Circ. J. (1979) [Pubmed]
  18. Supranormal cardiac output in the dopamine- and dobutamine-dependent preterm infant. Lopez, S.L., Leighton, J.O., Walther, F.J. Pediatric cardiology. (1997) [Pubmed]
  19. The heart of the icefish: bioconstruction and adaptation. Zummo, G., Acierno, R., Agnisola, C., Tota, B. Braz. J. Med. Biol. Res. (1995) [Pubmed]
  20. Gas exchange and pulmonary haemodynamic responses to fat emulsions in acute respiratory distress syndrome. Masclans, J.R., Iglesia, R., Bermejo, B., Picó, M., Rodriguez-Roisin, R., Planas, M. Intensive care medicine. (1998) [Pubmed]
  21. Renormalization of high cardiac output and of left ventricular size following long-term recombinant human erythropoietin treatment of anemic dialyzed uremic patients. Cannella, G., La Canna, G., Sandrini, M., Gaggiotti, M., Nordio, G., Movilli, E., Maiorca, R. Clin. Nephrol. (1990) [Pubmed]
  22. Physiological profile and predictors of cycling performance in ultra-endurance triathletes. Whyte, G., Lumley, S., George, K., Gates, P., Sharma, S., Prasad, K., McKenna, W.J. The Journal of sports medicine and physical fitness. (2000) [Pubmed]
  23. Rest and exercise hemodynamics after the Ross procedure: an echocardiographic study. da Costa, F., Haggi, H., Pinton, R., Lenke, W., Adam, E., Costa, I.S. Journal of cardiac surgery. (1998) [Pubmed]
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