The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
MeSH Review

Neurobehavioral Manifestations

 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

Disease relevance of Neurobehavioral Manifestations

 

Psychiatry related information on Neurobehavioral Manifestations

 

High impact information on Neurobehavioral Manifestations

 

Chemical compound and disease context of Neurobehavioral Manifestations

  • Previous administration of D-serine to schizophrenic patients taking nonclozapine antipsychotics improved positive, negative, and cognitive symptoms, whereas the partial agonist D-cycloserine improved negative symptoms of patients taking conventional antipsychotics but worsened symptoms in clozapine-treated patients [15].
  • BACKGROUND: Phencycline (PCP, "angel dust") and other noncompetitive antagonists of N-methyl-D-aspartate (NMDA)-type glutamatergic neurotransmission induce psychotic effects in humans that closely resemble positive, negative, and cognitive symptoms of schizophrenia [16].
  • CSF 5-HIAA, serum cortisol, and age differentially predict vegetative and cognitive symptoms in depression [17].
  • The results showed that depressed patients had lower platelet serotonin (5-HT) uptake site density values than controls and that 5-HT uptake site density values were inversely correlated with the severity of cognitive symptoms of depression [18].
  • Improvements in overall, negative, and cognitive symptoms were significantly higher for risperidone compared with haloperidol (p <.001), whereas improvements across all symptoms were comparable for quetiapine and haloperidol [19].
 

Biological context of Neurobehavioral Manifestations

  • Dysfunction in this system in humans may give rise to affective and cognitive symptoms which may, if initiated by a postpartum fall in oestrogen and progesterone concentrations, constitute the core pathophysiology of puerperal psychosis [20].
 

Anatomical context of Neurobehavioral Manifestations

 

Gene context of Neurobehavioral Manifestations

  • Cognitive manifestations of Huntington disease in relation to genetic structure and clinical onset [22].
  • These results support the hypothesis that CNTF infusion into the striatum of HD patients not only could block the degeneration of neurons but also alleviated motor and cognitive symptoms associated with persistent neuronal dysfunction [23].
  • Platelet 5-HT2 receptor density values were higher in depressed patients than controls, and there was a trend toward a direct correlation between the cognitive symptoms of depression and 5-HT2 receptor density values [18].
  • However, in this family, an individual whose child carries the PS1 mutation died at age 67 years free from cognitive symptoms, indicating a very late age at onset or nonpenetration of the disease [24].
  • The extent to which anxiety, irritability and depression were differentiated as separate entities associated with characteristic patterns of somatic and cognitive symptoms by field dependent (FD) and field independent (FI) normal female subjects was studied with the Hidden Figures Test and Unpleasant Emotions Questionnaire [25].
 

Analytical, diagnostic and therapeutic context of Neurobehavioral Manifestations

References

  1. Identification of a locus on chromosome 14q for idiopathic basal ganglia calcification (Fahr disease). Geschwind, D.H., Loginov, M., Stern, J.M. Am. J. Hum. Genet. (1999) [Pubmed]
  2. Adjuvant galantamine to risperidone improves negative and cognitive symptoms in a patient presenting with schizophrenialike psychosis after traumatic brain injury. Bennouna, M., Greene, V.B., Defranoux, L. Journal of clinical psychopharmacology. (2005) [Pubmed]
  3. Behavioral effects of organophosphate in man. Levin, H.S., Rodnitzky, R.L. Clin. Toxicol. (1976) [Pubmed]
  4. Cognitive symptoms and correlates of physical disability in individuals with multiple sclerosis. Fraser, C., Stark, S. The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses. (2003) [Pubmed]
  5. Progressive alterations in the hypothalamic-pituitary-adrenal axis in the R6/2 transgenic mouse model of Huntington's disease. Björkqvist, M., Petersén, A., Bacos, K., Isaacs, J., Norlén, P., Gil, J., Popovic, N., Sundler, F., Bates, G.P., Tabrizi, S.J., Brundin, P., Mulder, H. Hum. Mol. Genet. (2006) [Pubmed]
  6. Effects of acute nicotine administration on behavioral inhibition in adolescents with attention-deficit/hyperactivity disorder. Potter, A.S., Newhouse, P.A. Psychopharmacology (Berl.) (2004) [Pubmed]
  7. Effects of dopamine D2 receptor Ser311Cys polymorphism and clinical factors on risperidone efficacy for positive and negative symptoms and social function. Lane, H.Y., Lee, C.C., Chang, Y.C., Lu, C.T., Huang, C.H., Chang, W.H. Int. J. Neuropsychopharmacol. (2004) [Pubmed]
  8. Velnacrine for the treatment of Alzheimer's disease: a double-blind, placebo-controlled trial. The Mentane Study Group. Zemlan, F.P. Journal of neural transmission (Vienna, Austria : 1996) (1996) [Pubmed]
  9. Pharmacologic alternatives to psychostimulants for the treatment of attention-deficit/hyperactivity disorder. Popper, C.W. Child and adolescent psychiatric clinics of North America. (2000) [Pubmed]
  10. Efficacy of cholinesterase inhibitors in the treatment of neuropsychiatric symptoms and functional impairment in Alzheimer disease: a meta-analysis. Trinh, N.H., Hoblyn, J., Mohanty, S., Yaffe, K. JAMA (2003) [Pubmed]
  11. NMDA receptor hypofunction produces concomitant firing rate potentiation and burst activity reduction in the prefrontal cortex. Jackson, M.E., Homayoun, H., Moghaddam, B. Proc. Natl. Acad. Sci. U.S.A. (2004) [Pubmed]
  12. Impaired synaptic plasticity in mice carrying the Huntington's disease mutation. Usdin, M.T., Shelbourne, P.F., Myers, R.M., Madison, D.V. Hum. Mol. Genet. (1999) [Pubmed]
  13. Systemic lupus erythematosus in three ethnic groups. X. Measuring cognitive impairment with the cognitive symptoms inventory. Alarcón, G.S., Cianfrini, L., Bradley, L.A., Sanchez, M.L., Brooks, K., Friedman, A.W., Baethge, B.A., Fessler, B.J., Bastian, H.M., Roseman, J.M., McGwin, G., Reveille, J.D. Arthritis Rheum. (2002) [Pubmed]
  14. Phenotype of schizophrenia: a review and formulation. Tamminga, C.A., Holcomb, H.H. Mol. Psychiatry (2005) [Pubmed]
  15. D-serine added to clozapine for the treatment of schizophrenia. Tsai, G.E., Yang, P., Chung, L.C., Tsai, I.C., Tsai, C.W., Coyle, J.T. The American journal of psychiatry. (1999) [Pubmed]
  16. A.E. Bennett Research Award. Reversal of phencyclidine-induced effects by glycine and glycine transport inhibitors. Javitt, D.C., Balla, A., Sershen, H., Lajtha, A. Biol. Psychiatry (1999) [Pubmed]
  17. CSF 5-HIAA, serum cortisol, and age differentially predict vegetative and cognitive symptoms in depression. Faustman, W.O., Faull, K.F., Whiteford, H.A., Borchert, C., Csernansky, J.G. Biol. Psychiatry (1990) [Pubmed]
  18. Platelet serotonin markers and depressive symptomatology. Sheline, Y.I., Bardgett, M.E., Jackson, J.L., Newcomer, J.W., Csernansky, J.G. Biol. Psychiatry (1995) [Pubmed]
  19. Effectiveness of antipsychotic treatments for schizophrenia: interim 6-month analysis from a prospective observational study (IC-SOHO) comparing olanzapine, quetiapine, risperidone, and haloperidol. Dossenbach, M., Erol, A., el Mahfoud Kessaci, M., Shaheen, M.O., Sunbol, M.M., Boland, J., Hodge, A., O'Halloran, R.A., Bitter, I. The Journal of clinical psychiatry. (2004) [Pubmed]
  20. Dopamine efflux in the rat nucleus accumbens evoked by dopamine receptor stimulation in the entorhinal cortex is modulated by oestradiol and progesterone. Saigusa, T., Takada, K., Baker, S.C., Kumar, R., Stephenson, J.D. Synapse (1997) [Pubmed]
  21. Decreased beta-amyloid1-42 and increased tau levels in cerebrospinal fluid of patients with Alzheimer disease. Sunderland, T., Linker, G., Mirza, N., Putnam, K.T., Friedman, D.L., Kimmel, L.H., Bergeson, J., Manetti, G.J., Zimmermann, M., Tang, B., Bartko, J.J., Cohen, R.M. JAMA (2003) [Pubmed]
  22. Cognitive manifestations of Huntington disease in relation to genetic structure and clinical onset. Jason, G.W., Suchowersky, O., Pajurkova, E.M., Graham, L., Klimek, M.L., Garber, A.T., Poirier-Heine, D. Arch. Neurol. (1997) [Pubmed]
  23. Restoration of cognitive and motor functions by ciliary neurotrophic factor in a primate model of Huntington's disease. Mittoux, V., Joseph, J.M., Conde, F., Palfi, S., Dautry, C., Poyot, T., Bloch, J., Deglon, N., Ouary, S., Nimchinsky, E.A., Brouillet, E., Hof, P.R., Peschanski, M., Aebischer, P., Hantraye, P. Hum. Gene Ther. (2000) [Pubmed]
  24. Wide range of disease onset in a family with Alzheimer disease and a His163Tyr mutation in the presenilin-1 gene. Axelman, K., Basun, H., Lannfelt, L. Arch. Neurol. (1998) [Pubmed]
  25. Field dependence and the differentiation of affective states. Parkes, K.R. The British journal of psychiatry : the journal of mental science. (1981) [Pubmed]
  26. High-dose glycine added to olanzapine and risperidone for the treatment of schizophrenia. Heresco-Levy, U., Ermilov, M., Lichtenberg, P., Bar, G., Javitt, D.C. Biol. Psychiatry (2004) [Pubmed]
  27. Glutamate-mediated excitotoxicity and neurodegeneration in Alzheimer's disease. Hynd, M.R., Scott, H.L., Dodd, P.R. Neurochem. Int. (2004) [Pubmed]
  28. Neuropsychological functioning following fetal striatal transplantation in Huntington's chorea: three case presentations. Philpott, L.M., Kopyov, O.V., Lee, A.J., Jacques, S., Duma, C.M., Caine, S., Yang, M., Eagle, K.S. Cell transplantation. (1997) [Pubmed]
  29. Self-rated psychiatric symptoms in patients operated on because of primary hyperparathyroidism and in patients with long-standing mild hypercalcemia. Joborn, C., Hetta, J., Lind, L., Rastad, J., Akerström, G., Ljunghall, S. Surgery (1989) [Pubmed]
  30. Effect of hormone replacement therapy on self-reported cognitive symptoms: results from the Postmenopausal Estrogen/Progestin Interventions (PEPI) trial. Reboussin, B.A., Greendale, G.A., Espeland, M.A. Climacteric : the journal of the International Menopause Society. (1998) [Pubmed]
 
WikiGenes - Universities