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Disease relevance of Amorphophallus

  • The dichloromethane extract of Amorphophallus bequaertii inhibited the growth of Mycobacterium tuberculosis with a MIC of 100 microg/ml and the methanolic extract of Rubus rigidus inhibited the activity of both enzymes HIV1-reverse transcriptase (HIV1-RT) and TK p56(lck) [1].

High impact information on Amorphophallus


Biological context of Amorphophallus

  • Effect of the degree of acetylation (DA) on the gelation behaviors on addition of sodium carbonate for native and acetylated konjac glucomannan (KGM) samples with a DA range from 1.38 to 10.1 wt % synthesized using acetic anhydride in the presence of pyridine as catalyst was studied by dynamic viscoelastic measurements [5].
  • AIM: To evaluate the effects of konjac extract (KE) on insulin sensitivity in insulin resistance (IR) rats induced by high fat diet (HFD) [6].

Anatomical context of Amorphophallus


Associations of Amorphophallus with chemical compounds


Gene context of Amorphophallus


Analytical, diagnostic and therapeutic context of Amorphophallus


  1. Screening of African medicinal plants for antimicrobial and enzyme inhibitory activity. Tshibangu, J.N., Chifundera, K., Kaminsky, R., Wright, A.D., König, G.M. Journal of ethnopharmacology. (2002) [Pubmed]
  2. Effect of short-term ingestion of konjac glucomannan on serum cholesterol in healthy men. Arvill, A., Bodin, L. Am. J. Clin. Nutr. (1995) [Pubmed]
  3. Regulation of endo-acting glycosyl hydrolases in the hyperthermophilic bacterium Thermotoga maritima grown on glucan- and mannan-based polysaccharides. Chhabra, S.R., Shockley, K.R., Ward, D.E., Kelly, R.M. Appl. Environ. Microbiol. (2002) [Pubmed]
  4. Interaction of bile acids, phospholipids, cholesterol and triglyceride with dietary fibers in the small intestine of rats. Ebihara, K., Schneeman, B.O. J. Nutr. (1989) [Pubmed]
  5. Effect of degree of acetylation on gelation of konjac glucomannan. Gao, S., Nishinari, K. Biomacromolecules (2004) [Pubmed]
  6. Effects of konjac extract on insulin sensitivity in high fat diet rats. Mao, C.P., Xie, M.L., Gu, Z.L. Acta Pharmacol. Sin. (2002) [Pubmed]
  7. Degradation of konjac glucomannan by enzymes in human feces and formation of short-chain fatty acids by intestinal anaerobic bacteria. Matsuura, Y. J. Nutr. Sci. Vitaminol. (1998) [Pubmed]
  8. Hypocholesterolemia and growth-depression in chicks fed guar gum and konjac mannan. Rogel, A.M., Vohra, P. J. Nutr. (1983) [Pubmed]
  9. Use of glucomannan for the separation of DNA fragments by capillary electrophoresis. Izumi, T., Yamaguchi, M., Yoneda, K., Isobe, T., Okuyama, T., Shinoda, T. Journal of chromatography. A. (1993) [Pubmed]
  10. Release characteristics of dibucaine dispersed in konjac gels. Nakano, M., Takikawa, K., Arita, T. J. Biomed. Mater. Res. (1979) [Pubmed]
  11. Ignisphaera aggregans gen. nov., sp. nov., a novel hyperthermophilic crenarchaeote isolated from hot springs in Rotorua and Tokaanu, New Zealand. Niederberger, T.D., Götz, D.K., McDonald, I.R., Ronimus, R.S., Morgan, H.W. Int. J. Syst. Evol. Microbiol. (2006) [Pubmed]
  12. Flow field-flow fractionation and characterization of ionic and neutral polysaccharides of vegetable and microbial origin. Benincasa, M.A., Cartoni, G., Delle Fratte, C. Journal of chromatography. A. (2002) [Pubmed]
  13. Development of electrochemical biosensor based on tyrosinase immobilized in composite biopolymeric film. Tembe, S., Karve, M., Inamdar, S., Haram, S., Melo, J., D'Souza, S.F. Anal. Biochem. (2006) [Pubmed]
  14. Molecular cloning and characterization of a novel mannose-binding lectin gene from Amorphophallus konjac. Fei, J., Liao, Z., Chai, Y., Pang, Y., Yao, J., Sun, X., Tang, K. Mol. Biol. Rep. (2003) [Pubmed]
  15. Influence of dietary fiber (konjac mannan) on absorption of vitamin B12 and vitamin E. Doi, K., Matsuura, M., Kawara, A., Tanaka, T., Baba, S. Tohoku J. Exp. Med. (1983) [Pubmed]
  16. Sustained release of dibucaine from konjac gels after rectal administration to rats. Nakano, M., Takikawa, K., Arita, T. Chem. Pharm. Bull. (1979) [Pubmed]
  17. Respiratory sensitization to konjac flour in guinea pigs. Werley, M.S., Burleigh-Flayer, H., Mount, E.A., Kotkoskie, L.A. Toxicology (1997) [Pubmed]
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