Disease relevance of Amorphophallus

• The dichloromethane extract of Amorphophallus bequaertii inhibited the growth of Mycobacterium tuberculosis with a MIC of 100 microg/ml and the methanolic extract of Rubus rigidus inhibited the activity of both enzymes HIV1-reverse transcriptase (HIV1-RT) and TK p56(lck) [1].

High impact information on Amorphophallus

• Effect of short-term ingestion of konjac glucomannan on serum cholesterol in healthy men [2].
• An extracellular mannanase encoded by man5 (TM1227) was expressed on carob galactomannan and konjac glucomannan and to a lesser extent on carboxymethyl cellulose [3].
• An unexpected result was the finding that the cel5A (TM1751) and cel5B (TM1752) genes, which encode putative intracellular beta-specific endoglucanases, were induced only when T. maritima was grown on konjac glucomannan [3].
• In this study, T. maritima was grown on a range of polysaccharides, including barley beta-glucan, carboxymethyl cellulose, carob galactomannan, konjac glucomannan, and potato starch [3].
• In the present study, the interaction of bile acids with guar gum (GG), konjac mannan (KM) and chitosan (CH) was determined [4].

Biological context of Amorphophallus

• Effect of the degree of acetylation (DA) on the gelation behaviors on addition of sodium carbonate for native and acetylated konjac glucomannan (KGM) samples with a DA range from 1.38 to 10.1 wt % synthesized using acetic anhydride in the presence of pyridine as catalyst was studied by dynamic viscoelastic measurements [5].
• AIM: To evaluate the effects of konjac extract (KE) on insulin sensitivity in insulin resistance (IR) rats induced by high fat diet (HFD) [6].

Anatomical context of Amorphophallus

• The konjac glucomannan was degraded almost 100% by soluble enzymes in human feces to give 4-O-beta-D-mannopyranosyl-D-mannopyranose (beta-1,4-D-mannobiose), 4-O-beta-D-glucopyranosyl-D-glucopyranose (cellobiose), 4-O-beta-D-glucopyranosyl-D-mannopyranose, and small amounts of glucose and mannose [7].

Associations of Amorphophallus with chemical compounds

• Hepatic triglyceride levels were higher for chicks fed konjac mannan, but no significant differences in fasting plasma glucose were observed [8].
• Glucomannan, a natural polysaccharide extracted from Amorphophallus konjac, was employed as a sieving additive for the separation of restriction DNA fragments in capillary electrophoresis [9].
• Release characteristics of dibucaine dispersed in konjac gels [10].
• Strain AQ1.S1(T) utilized starch, trypticase peptone, lactose, glucose, konjac glucomannan, mannose, galactose, maltose, glycogen and beta-cyclodextrin as carbon sources [11].
• Clear evidence of some physico-chemical properties of the polysaccharides is given by the study of the effect of the carrier ionic strength on salep, oxidized salep and konjac, carboxymethylcellulose and hyaluronic acid [12].

Gene context of Amorphophallus

• The enzyme tyrosinase was extracted from a plant source Amorphophallus companulatus and immobilized in a novel composite of two biopolymers: agarose and guar gum [13].
• Molecular cloning and characterization of a novel mannose-binding lectin gene from Amorphophallus konjac [14].
• The absorption rate of vitamin E into the intestine was reduced when konjac mannan was added to the test meals, but that of vitamin B12 was not reduced in normal or diabetic subjects [15].

Analytical, diagnostic and therapeutic context of Amorphophallus

• Sustained release of dibucaine from konjac gels after rectal administration to rats [16].
• Groups of guinea pigs were randomly assigned to a negative control, a konjac flour exposure group, or a positive control group exposed to trimellitic anhydride (TMA) [17].

References