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MeSH Review

Lower Gastrointestinal Tract

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Disease relevance of Lower Gastrointestinal Tract


High impact information on Lower Gastrointestinal Tract


Chemical compound and disease context of Lower Gastrointestinal Tract


Biological context of Lower Gastrointestinal Tract


Anatomical context of Lower Gastrointestinal Tract


Associations of Lower Gastrointestinal Tract with chemical compounds


Gene context of Lower Gastrointestinal Tract

  • Glucagon-like peptide 1 (GLP-1) is a physiological incretin hormone from the lower gastrointestinal tract, partially explaining the augmented insulin response after oral compared to intravenous glucose administration in normal humans [19].
  • Mucin histochemistry of the lower gastrointestinal tract [20].
  • This chapter is focused on the relatively recent investigations demonstrating a pharmacological and pathophysiological role for bFGF and PDGF in ulcerative and inflammatory lesions in the upper and lower GI tract [21].
  • GPX-GI and GPX-1 activities were uniformly distributed in the middle and lower GI tract and with respect to the crypt to villus axis [22].
  • 1. The toxic effects of nonsteroidal anti-inflammatory drugs for the lower gastrointestinal tract share certain features with inflammatory processes, suggesting that the release of inflammation cytokines such as TNF-alpha may damage the intestine [23].


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  13. Microflora trigger colitis in mice deficient in selenium-dependent glutathione peroxidase and induce Gpx2 gene expression. Esworthy, R.S., Binder, S.W., Doroshow, J.H., Chu, F.F. Biol. Chem. (2003) [Pubmed]
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  16. Randomized clinical trial of the effects of preoperative and postoperative oral nutritional supplements on clinical course and cost of care. Smedley, F., Bowling, T., James, M., Stokes, E., Goodger, C., O'Connor, O., Oldale, C., Jones, P., Silk, D. The British journal of surgery. (2004) [Pubmed]
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  18. The combination of oral amphotericin B with azoles prevents the emergence of resistant Candida species in neutropenic patients. Paterson, P.J., McWhinney, P.H., Potter, M., Kibbler, C.C., Prentice, H.G. Br. J. Haematol. (2001) [Pubmed]
  19. Glucagon-like peptide 1 (GLP-1): a potent gut hormone with a possible therapeutic perspective. Nauck, M.A. Acta diabetologica. (1998) [Pubmed]
  20. Mucin histochemistry of the lower gastrointestinal tract. Shah, M., Shrikhande, S.S. Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology. (1989) [Pubmed]
  21. Basic fibroblast growth factor and PDGF in GI diseases. Szabo, S., Sandor, Z. Baillieres Clin. Gastroenterol. (1996) [Pubmed]
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  23. Increase in tumor necrosis factor-alpha production linked to the toxicity of indomethacin for the rat small intestine. Bertrand, V., Guimbaud, R., Tulliez, M., Mauprivez, C., Sogni, P., Couturier, D., Giroud, J.P., Chaussade, S., Chauvelot-Moachon, L. Br. J. Pharmacol. (1998) [Pubmed]
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