Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

MeSH Review:

Histamine Release

Nielsen, B.W. et al., Thiel, H. et al., Ebertz, J.M. et al., Nolte, H. et al., Alam, R. et al., et al.

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Histamine Release

After incubation with a live influenza A (H3N2) virus, calcium ionophore A23187 (0.5, 1.0, and 1.5 microgram/ml)-induced leukocyte histamine release (HR) was enhanced (p less than 0.05) [1].
Toxicity to basophils was considered to be manifested by the increasing inability of 2-deoxyglucose (2DG) to inhibit histamine release (HR) at increasing concentrations of A23 [2].
Nine adult patients suffering from severe atopic dermatitis (AD) and increased total serum IgE were treated with recombinant human interferon-alpha 2A (Roferon-AR; IFN-alpha-2A) 3 x 10(6) units daily for 21 d to study the effect upon serum IgE, basophil histamine release (HR), eosinophil-derived proteins in serum, and clinical symptoms [3].

High impact information on Histamine Release

We have shown that MNC also produced a histamine release inhibitory factor (HRIF), and that the synthesis is augmented by culture with physiologic concentrations of histamine (10(-10) to 10(-6) M) and by the mitogen concanavalin A (Con A) [4].
We compared the effects of drugs, modulating arachidonic acid (AA) metabolism, on histamine release (HR) from human basophils stimulated by anti-IgE antibody or C5a anaphylatoxin [5].
We have characterized the effects of eight different drugs on the IgE-mediated histamine release (HR) and leukotriene C4 (LTC4R) from human basophils [6].
Previous studies demonstrated that antidromic stimulation results in substance P (SP) release from nerve endings, SP stimulates histamine release (HR) from rat mast cells in vitro, and intradermal SP in humans produces wheals identical to those induced by histamine [7].
We have studied the effect of nitric oxide (NO) and hydrogen peroxide (H(2)O(2)), two reactive oxygen species (ROS) on histamine release (HR) from RBL-2H3 cells, a rat mucosal-type mast cell line [8].

Biological context of Histamine Release

We have studied the allergen-specific in vitro histamine release (HR) in 38 flour-sensitive bakers and in 10 controls without occupational exposure after whole blood incubation with native wheat and rye flour and compared the results with the findings in RAST, skin and bronchial provocation tests [9].

Anatomical context of Histamine Release

To investigate if these effects may be partly mediated by histamine release (HR) we studied the influence of SP on HR from nasal mucosa of subjects with and without allergic rhinitis using an in vitro organ culture system [10].
Interleukin 3 (IL3) is known to stimulate progenitor cell proliferation and maturation as well as differentiated cell functions, e.g. direct or anti-IgE-mediated histamine release (HR) [11].

Associations of Histamine Release with chemical compounds

BAL histamine and tryptase concentrations and in vitro histamine release (HR) after stimulation with anti-IgE, allergen, A23187, conconavalin A and substance P were compared [12].
Histamine release was then performed on the passively sensitized cells and the results were compared with those of bronchial provocation test (BPT), allergen-specific serum IgE (RAST), skin prick test (SPT), and conventional histamine release test (HR) [13].
The basophil histamine release test (BHRT) yielded positive results in 13/14 (93%) patients, whereas commercial latex RAST was positive in only 9/15 (60%) patients [14].
Isolated mononuclear cells showed a significantly decreased histamine release (HR) when stimulated with A23187 and grass [15].
Compound 48/80-induced histamine release (HR) from the isolated perfused rat heart was markedly and significantly inhibited by picumast (PIC), possibly by acting as a calmodulin antagonist (CMA) or membrane stabilizer [16].

Gene context of Histamine Release

The aim of this study was to investigate the anti-inflammatory role of the Substance P-antagonists (SPAs) through the inhibition of histamine release (HR) and TNF-alpha production from mast cell [17].
The neuropeptide substance P (SP) is a mediator of neuro-inflammation and can play a role by induction of histamine release (HR) and TNF-alpha [18].
Fractions from each chromatographic step were assayed for histamine release factor activity (HRF) [19].

Analytical, diagnostic and therapeutic context of Histamine Release

Airborne particles were collected by air sampling for 2 hours and cat allergen, Fel d 1, was quantified biologically by basophil histamine release test (HR test) and immunochemically by enzyme linked immunosorbent assay (ELISA) [20].

References

Effect of influenza A virus on leukocyte histamine release. Busse, W.W., Swenson, C.A., Borden, E.C., Treuhaft, M.W., Dick, E.C. J. Allergy Clin. Immunol. (1983) [Pubmed]
Cytotoxicity of ionophore A23187 for basophils and other human blood cells. Pruzansky, J.J., Patterson, R. J. Allergy Clin. Immunol. (1979) [Pubmed]
Interferon therapy for atopic dermatitis reduces basophil histamine release, but does not reduce serum IgE or eosinophilic proteins. Nielsen, B.W., Reimert, C.M., Hammer, R., Schiøtz, P.O., Thestrup-Pedersen, K. Allergy (1994) [Pubmed]
Identification of a histamine release inhibitory factor produced by human mononuclear cells in vitro. Alam, R., Grant, J.A., Lett-Brown, M.A. J. Clin. Invest. (1988) [Pubmed]
Complement- and IgE-mediated release of histamine from basophils in vitro. V. Differential effects of drugs modulating arachidonic acid metabolism. Farnam, J., Grant, J.A., Lett-Brown, M.A., Hunt, C., Thueson, D.O., Giclas, P.C. J. Immunol. (1985) [Pubmed]
The pharmacologic modulation of mediator release from human basophils. Warner, J.A., MacGlashan, D.W., Peters, S.P., Kagey-Sobotka, A., Lichtenstein, L.M. J. Allergy Clin. Immunol. (1988) [Pubmed]
Substance P-induced histamine release in human cutaneous mast cells. Ebertz, J.M., Hirshman, C.A., Kettelkamp, N.S., Uno, H., Hanifin, J.M. J. Invest. Dermatol. (1987) [Pubmed]
Effects of nitric oxide and hydrogen peroxide on histamine release from RBL-2H3 cells. Wan, B.Y., Peh, K.H., Ho, M., Assem, E.S. Biochem. Pharmacol. (2001) [Pubmed]
Allergen-specific histamine release from whole blood in flour-sensitive bakers. Thiel, H., Zimmermann, I., Rasche, B., Ulmer, W.T. Respiration; international review of thoracic diseases. (1982) [Pubmed]
Substance P induced histamine release from nasal mucosa of subjects with and without allergic rhinitis. Hanf, G., Schierhorn, K., Brunnée, T., Noga, O., Verges, D., Kunkel, G. Inflamm. Res. (2000) [Pubmed]
Histamine release from basophils after in vivo application of recombinant human interleukin-3 in man. Merget, R.D., Maurer, A.B., Koch, U., Ganser, A., Ottmann, O.G., Schultze-Werninghaus, G., Seipelt, G., Zachgo, W., Hoelzer, D., Meier-Sydow, J. Int. Arch. Allergy Appl. Immunol. (1990) [Pubmed]
Histamine release from bronchoalveolar lavage cells from asthmatic subjects after allergen challenge and relationship to the late asthmatic response. Heaney, L.G., Cross, L.J., Ennis, M. Clin. Exp. Allergy (1998) [Pubmed]
Passive sensitization of basophil leukocytes from non-atopic adult by plasma from allergic children. Nolte, H., Stafanger, G., Skov, P.S., Schiøtz, P.O. Allergy (1988) [Pubmed]
Basophil histamine release and lymphocyte proliferation tests in latex contact urticaria. In vitro tests in latex contact urticaria. Turjanmaa, K., Räsänen, L., Lehto, M., Mäkinen-Kiljunen, S., Reunala, T. Allergy (1989) [Pubmed]
Increased numbers of circulating basophils with decreased releasability after administration of rhG-CSF to allergic patients. Pedersen, M., Kristensen, K.S., Clementsen, P., Olsen, O.T., Skov, P.S., Permin, H., Norn, S. Agents Actions (1994) [Pubmed]
Effect of picumast on histamine release from rat cardiac and peritoneal mast cells. Wan, B.Y., Peh, K.H., Assem, E.S. Agents Actions (1991) [Pubmed]
Mast cell production of TNF-alpha induced by substance P evidence for a modulatory role of substance P-antagonists. Cocchiara, R., Lampiasi, N., Albeggiani, G., Bongiovanni, A., Azzolina, A., Geraci, D. J. Neuroimmunol. (1999) [Pubmed]
Inhibitory effect of neuraminidase on SP-induced histamine release and TNF-alpha mRNA in rat mast cells: evidence of a receptor-independent mechanism. Cocchiara, R., Bongiovanni, A., Albeggiani, G., Azzolina, A., Lampiasi, N., Di Blasi, F., Geraci, D. J. Neuroimmunol. (1997) [Pubmed]
Isolation of a lipid-soluble histamine release factor from human platelets. Proudfoot, A.E., Gatto, R., Wells, T.N., Bacon, K.B. Biochem. Biophys. Res. Commun. (1994) [Pubmed]
Effect of two different types of vacuum cleaners on airborne Fel d 1 levels. Rønborg, S.M., Poulsen, L.K., Skov, P.S., Mosbech, H. Ann. Allergy Asthma Immunol. (1999) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.