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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Histamine Release

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Disease relevance of Histamine Release


High impact information on Histamine Release


Biological context of Histamine Release


Anatomical context of Histamine Release


Associations of Histamine Release with chemical compounds


Gene context of Histamine Release

  • The aim of this study was to investigate the anti-inflammatory role of the Substance P-antagonists (SPAs) through the inhibition of histamine release (HR) and TNF-alpha production from mast cell [17].
  • The neuropeptide substance P (SP) is a mediator of neuro-inflammation and can play a role by induction of histamine release (HR) and TNF-alpha [18].
  • Fractions from each chromatographic step were assayed for histamine release factor activity (HRF) [19].

Analytical, diagnostic and therapeutic context of Histamine Release


  1. Effect of influenza A virus on leukocyte histamine release. Busse, W.W., Swenson, C.A., Borden, E.C., Treuhaft, M.W., Dick, E.C. J. Allergy Clin. Immunol. (1983) [Pubmed]
  2. Cytotoxicity of ionophore A23187 for basophils and other human blood cells. Pruzansky, J.J., Patterson, R. J. Allergy Clin. Immunol. (1979) [Pubmed]
  3. Interferon therapy for atopic dermatitis reduces basophil histamine release, but does not reduce serum IgE or eosinophilic proteins. Nielsen, B.W., Reimert, C.M., Hammer, R., Schiøtz, P.O., Thestrup-Pedersen, K. Allergy (1994) [Pubmed]
  4. Identification of a histamine release inhibitory factor produced by human mononuclear cells in vitro. Alam, R., Grant, J.A., Lett-Brown, M.A. J. Clin. Invest. (1988) [Pubmed]
  5. Complement- and IgE-mediated release of histamine from basophils in vitro. V. Differential effects of drugs modulating arachidonic acid metabolism. Farnam, J., Grant, J.A., Lett-Brown, M.A., Hunt, C., Thueson, D.O., Giclas, P.C. J. Immunol. (1985) [Pubmed]
  6. The pharmacologic modulation of mediator release from human basophils. Warner, J.A., MacGlashan, D.W., Peters, S.P., Kagey-Sobotka, A., Lichtenstein, L.M. J. Allergy Clin. Immunol. (1988) [Pubmed]
  7. Substance P-induced histamine release in human cutaneous mast cells. Ebertz, J.M., Hirshman, C.A., Kettelkamp, N.S., Uno, H., Hanifin, J.M. J. Invest. Dermatol. (1987) [Pubmed]
  8. Effects of nitric oxide and hydrogen peroxide on histamine release from RBL-2H3 cells. Wan, B.Y., Peh, K.H., Ho, M., Assem, E.S. Biochem. Pharmacol. (2001) [Pubmed]
  9. Allergen-specific histamine release from whole blood in flour-sensitive bakers. Thiel, H., Zimmermann, I., Rasche, B., Ulmer, W.T. Respiration; international review of thoracic diseases. (1982) [Pubmed]
  10. Substance P induced histamine release from nasal mucosa of subjects with and without allergic rhinitis. Hanf, G., Schierhorn, K., Brunnée, T., Noga, O., Verges, D., Kunkel, G. Inflamm. Res. (2000) [Pubmed]
  11. Histamine release from basophils after in vivo application of recombinant human interleukin-3 in man. Merget, R.D., Maurer, A.B., Koch, U., Ganser, A., Ottmann, O.G., Schultze-Werninghaus, G., Seipelt, G., Zachgo, W., Hoelzer, D., Meier-Sydow, J. Int. Arch. Allergy Appl. Immunol. (1990) [Pubmed]
  12. Histamine release from bronchoalveolar lavage cells from asthmatic subjects after allergen challenge and relationship to the late asthmatic response. Heaney, L.G., Cross, L.J., Ennis, M. Clin. Exp. Allergy (1998) [Pubmed]
  13. Passive sensitization of basophil leukocytes from non-atopic adult by plasma from allergic children. Nolte, H., Stafanger, G., Skov, P.S., Schiøtz, P.O. Allergy (1988) [Pubmed]
  14. Basophil histamine release and lymphocyte proliferation tests in latex contact urticaria. In vitro tests in latex contact urticaria. Turjanmaa, K., Räsänen, L., Lehto, M., Mäkinen-Kiljunen, S., Reunala, T. Allergy (1989) [Pubmed]
  15. Increased numbers of circulating basophils with decreased releasability after administration of rhG-CSF to allergic patients. Pedersen, M., Kristensen, K.S., Clementsen, P., Olsen, O.T., Skov, P.S., Permin, H., Norn, S. Agents Actions (1994) [Pubmed]
  16. Effect of picumast on histamine release from rat cardiac and peritoneal mast cells. Wan, B.Y., Peh, K.H., Assem, E.S. Agents Actions (1991) [Pubmed]
  17. Mast cell production of TNF-alpha induced by substance P evidence for a modulatory role of substance P-antagonists. Cocchiara, R., Lampiasi, N., Albeggiani, G., Bongiovanni, A., Azzolina, A., Geraci, D. J. Neuroimmunol. (1999) [Pubmed]
  18. Inhibitory effect of neuraminidase on SP-induced histamine release and TNF-alpha mRNA in rat mast cells: evidence of a receptor-independent mechanism. Cocchiara, R., Bongiovanni, A., Albeggiani, G., Azzolina, A., Lampiasi, N., Di Blasi, F., Geraci, D. J. Neuroimmunol. (1997) [Pubmed]
  19. Isolation of a lipid-soluble histamine release factor from human platelets. Proudfoot, A.E., Gatto, R., Wells, T.N., Bacon, K.B. Biochem. Biophys. Res. Commun. (1994) [Pubmed]
  20. Effect of two different types of vacuum cleaners on airborne Fel d 1 levels. Rønborg, S.M., Poulsen, L.K., Skov, P.S., Mosbech, H. Ann. Allergy Asthma Immunol. (1999) [Pubmed]
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