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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
MeSH Review

Talus

 
 
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Disease relevance of Talus

  • Granulomatous infiltration of the talus and abnormal vitamin D and calcium metabolism in a patient with sarcoidosis: successful treatment with hydroxychloroquine [1].
  • Coexisting visceral and musculoskeletal anomalies included dextrocardia (3), atrial septal defect (1), congenital vertical talus (2), Sprengel's deformity (1), and multiple unilateral foot anomalies (1) [2].
  • Stenosing tenosynovitis of the flexor hallucis longus tendon and posterior impingement upon the os trigonum in ballet dancers [3].
  • A rare case of closed complete rupture of the flexor hallucis longus tendon at its groove in the posterior process of the talus is reported in a soccer player who developed pseudarthrosis of the posterolateral tubercle of the talus after a Shepherd's fracture [4].
  • The preoperative diagnosis of 16 patients was diabetic neuropathic arthropathy in seven patients, rheumatoid arthritis in three patients, post traumatic arthrosis in three patients, paraplegia with fixed equinovarus of the foot in two patients, and avascular necrosis of the talus in one patient [5].
 

High impact information on Talus

  • A HOX gene mutation in a family with isolated congenital vertical talus and Charcot-Marie-Tooth disease [6].
  • HOXD10 M319K mutation in a family with isolated congenital vertical talus [7].
  • Isolated foot anomalies, including congenital vertical talus, were shown recently to occur in heterozygous carriers of CDMP-1 (cartilage-derived morphogenetic protein-1) gene mutations [8].
  • Four examiners independently examined the coronal images as well as sagittal plane reconstructions for direct (bone-on-bone contact) and indirect (subchondral sclerosis or cysts) evidence of (1) extra-articular contact between the talus and the calcaneus in the sinus tarsi and (2) contact between the calcaneus and the fibula [9].
  • The Iowa Pleistocene snail, Discus macclintocki, is an endangered species that survives only in relictual populations on algific (cold-air) talus slopes in northeast Iowa and northwest Illinois in the central region of the USA [10].
 

Anatomical context of Talus

  • A saucer-shaped defect involving the lateral trochlear ridge of the talus and a radiopaque joint fragment were evident on radiographs of the left tarsus in a 6-month-old Rottweiler [11].
  • Closed complete rupture of the flexor hallucis longus tendon at the groove of the talus [4].
  • Some consultants (different consultants for different fracture regions) did not operate on any complex fracture of the proximal, mid, or distal humerus; proximal, mid, or distal radius or ulna; proximal, mid, or distal femur; proximal, mid, or distal tibia; calcaneum; peri-prosthetic; Lisfranc; or talus fracture during the specific time period [12].
  • Radiopaque markers were introduced into the tibia, talus, calcaneus, navicular, medial cuneiform, and first metatarsal bones [13].
  • Three cases of complete rupture of the flexor hallucis longus tendon near the metatarsophalangeal joint and three under the sustentaculum tali have been reported, but there have been no reports at the groove of the talus [4].
 

Associations of Talus with chemical compounds

 

Gene context of Talus

  • OBJECTIVE: This paper presents four generations of a family with radiographically demonstrated congenital vertical talus (CVT) in whom a HOXD10 gene mutation was identified [19].
  • Three reference pins were rigidly mounted in the calcaneus, talus, and shank segments to provide position data in 243 test situations [20].
  • Although the number in each group is small, it does not appear that the procedure has merit for the treatment of ankle arthritis from such diverse causes as trauma, rheumatoid arthritis, aseptic necrosis of the talus and talectomy [21].
  • Aneurysmal bone cysts localized in the talus are extremely rare [22].
  • At the present time, ECD seems to be the most effective treatment strategy for osteochondral defect of the talus [23].
 

Analytical, diagnostic and therapeutic context of Talus

References

  1. Granulomatous infiltration of the talus and abnormal vitamin D and calcium metabolism in a patient with sarcoidosis: successful treatment with hydroxychloroquine. DeSimone, D.P., Brilliant, H.L., Basile, J., Bell, N.H. Am. J. Med. (1989) [Pubmed]
  2. Congenital vertebral anomalies in ischiopagus and pyopagus conjoined twins. Spiegel, D.A., Ganley, T.J., Akbarnia, H., Drummond, D.S. Clin. Orthop. Relat. Res. (2000) [Pubmed]
  3. Stenosing tenosynovitis of the flexor hallucis longus tendon and posterior impingement upon the os trigonum in ballet dancers. Hamilton, W.G. Foot & ankle. (1982) [Pubmed]
  4. Closed complete rupture of the flexor hallucis longus tendon at the groove of the talus. Inokuchi, S., Usami, N. Foot & ankle international / American Orthopaedic Foot and Ankle Society [and] Swiss Foot and Ankle Society. (1997) [Pubmed]
  5. Retrograde intramedullary nailing for ankle arthrodesis. Moore, T.J., Prince, R., Pochatko, D., Smith, J.W., Fleming, S. Foot & ankle international / American Orthopaedic Foot and Ankle Society [and] Swiss Foot and Ankle Society. (1995) [Pubmed]
  6. A HOX gene mutation in a family with isolated congenital vertical talus and Charcot-Marie-Tooth disease. Shrimpton, A.E., Levinsohn, E.M., Yozawitz, J.M., Packard, D.S., Cady, R.B., Middleton, F.A., Persico, A.M., Hootnick, D.R. Am. J. Hum. Genet. (2004) [Pubmed]
  7. HOXD10 M319K mutation in a family with isolated congenital vertical talus. Dobbs, M.B., Gurnett, C.A., Pierce, B., Exner, G.U., Robarge, J., Morcuende, J.A., Cole, W.G., Templeton, P.A., Foster, B., Bowcock, A.M. J. Orthop. Res. (2006) [Pubmed]
  8. Variable hand and foot abnormalities in family with congenital vertical talus and CDMP-1 gene mutation. Dobbs, M.B., Gurnett, C.A., Robarge, J., Gordon, J.E., Morcuende, J.A., Bowcock, A.M. J. Orthop. Res. (2005) [Pubmed]
  9. Talocalcaneal and subfibular impingement in symptomatic flatfoot in adults. Malicky, E.S., Crary, J.L., Houghton, M.J., Agel, J., Hansen, S.T., Sangeorzan, B.J. The Journal of bone and joint surgery. American volume. (2002) [Pubmed]
  10. Phylogeography and conservation genetics of the Iowa pleistocene snail. Ross, T.K. Mol. Ecol. (1999) [Pubmed]
  11. Free chondral fragment involving the lateral trochlear ridge of the talus in a dog. Aron, D.N., Mahaffey, M.B., Rowland, G.N. J. Am. Vet. Med. Assoc. (1985) [Pubmed]
  12. Complex fractures, do we operate on enough to gain and maintain experience? Cutler, L., Boot, D.A. Injury. (2003) [Pubmed]
  13. Kinematics of the ankle/foot complex--Part 2: Pronation and supination. Lundberg, A., Svensson, O.K., Bylund, C., Goldie, I., Selvik, G. Foot & ankle. (1989) [Pubmed]
  14. The os trigonum syndrome: use of bone scan in the diagnosis. Johnson, R.P., Collier, B.D., Carrera, G.F. The Journal of trauma. (1984) [Pubmed]
  15. A 2-portal endoscopic approach for diagnosis and treatment of posterior ankle pathology. van Dijk, C.N., Scholten, P.E., Krips, R. Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association. (2000) [Pubmed]
  16. Corticosteroid-induced avascular necrosis of the talus. Adleberg, J.S., Smith, G.H. The Journal of foot surgery. (1991) [Pubmed]
  17. Bone scintigraphic findings of os trigonum: a prospective study of 100 soldiers on active duty. Sopov, V., Liberson, A., Groshar, D. Foot & ankle international / American Orthopaedic Foot and Ankle Society [and] Swiss Foot and Ankle Society. (2000) [Pubmed]
  18. Congenital talipes equinovarus in spina bifida: treatment and results. de Carvalho Neto, J., Dias, L.S., Gabrieli, A.P. Journal of pediatric orthopedics. (1996) [Pubmed]
  19. Congenital vertical talus in four generations of the same family. Levinsohn, E.M., Shrimpton, A.E., Cady, R.B., Packard, D.S., Hootnick, D.R. Skeletal radiology. (2004) [Pubmed]
  20. Predicting talocalcaneal joint orientations from talocalcaneal/talocrural joint orientations. Engsberg, J.R., Grimston, S.K., Wackwitz, J.H. J. Orthop. Res. (1988) [Pubmed]
  21. Management of arthritis of the ankle. An alternative of arthrodesis. Evanski, P.H., Waugh, T.R. Clin. Orthop. Relat. Res. (1977) [Pubmed]
  22. Aneurysmal bone cyst of the talus. Soreff, J. Acta orthopaedica Scandinavica. (1976) [Pubmed]
  23. Systematic review of treatment strategies for osteochondral defects of the talar dome. Verhagen, R.A., Struijs, P.A., Bossuyt, P.M., van Dijk, C.N. Foot and ankle clinics. (2003) [Pubmed]
  24. Prostaglandin E2 and collagenase release by cultured talus from type II collagen arthritis rats. Westmacott, D., Hawkes, J.E., Wadsworth, J., Cashin, C.H., Cline, A., Bradshaw, D., Bloxham, D.P. Agents Actions (1986) [Pubmed]
  25. Diagnostic imaging of trauma to the ankle and foot. Part III: Fractures and dislocations of the talus. Mitchell, M.J., Ho, C., Howard, B.A., Sartoris, D.J., Resnick, D. The Journal of foot surgery. (1989) [Pubmed]
  26. Analysis of arthroscopically assisted ankle arthrodesis. Zvijac, J.E., Lemak, L., Schurhoff, M.R., Hechtman, K.S., Uribe, J.W. Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association. (2002) [Pubmed]
 
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