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Disease relevance of Dextrocardia


High impact information on Dextrocardia

  • In all three patients the crossover segment was associated with a variant of the scimitar syndrome: right lung hypoplasia with dextrocardia, aberrant systemic arterial supply to the right lower lobe, and anomalous venous drainage of the whole of the right lung, and in two patients with eventration of the right diaphragm [6].
  • In addition, patients with hypertrophic cardiomyopathy, septal defects, dextrocardia, and anomalous pulmonary venous drainage have been reported anecdotally [7].
  • Secondary dextrocardia (39 cases) was due to intrathoracic displacement and, when caused by diaphragmatic hernia, was associated with cardiac malformations in 31% of cases [8].
  • In one patient with dextrocardia and the cardiac type of total anomalous pulmonary venous return, the abnormality was not recognized [9].
  • Right abnormal pulmonary venous return into the inferior vena cava associated with abnormal fissure, dextrocardia, and systemic arterial supply of a variable degree, are the characteristics of the scimitar syndrome [10].

Chemical compound and disease context of Dextrocardia


Biological context of Dextrocardia


Anatomical context of Dextrocardia


Gene context of Dextrocardia


  1. Transaortic closure of ventricular septal defect in patients with corrected transposition with pulmonary stenosis or atresia. Russo, P., Danielson, G.K., Driscoll, D.J. Circulation (1987) [Pubmed]
  2. Complete atrioventricular block in patients with atrioventricular discordance. Huhta, J.C., Maloney, J.D., Ritter, D.G., Ilstrup, D.M., Feldt, R.H. Circulation (1983) [Pubmed]
  3. Familial occurrence of agonadism and multiple internal malformations in phenotypically normal girls with 46,XY and 46,XX karyotypes, respectively: a new autosomal recessive syndrome. Kennerknecht, I., Sorgo, W., Oberhoffer, R., Teller, W.M., Mattfeldt, T., Negri, G., Vogel, W. Am. J. Med. Genet. (1993) [Pubmed]
  4. Isolated infundibuloarterial inversion (S,D,I): a newly recognized form of congenital heart disease. Foran, R.B., Belcourt, C., Nanton, M.A., Murphy, D.A., Weinberg, A.G., Liebman, J., Castañeda, A.R., Van Praagh, R. Am. Heart J. (1988) [Pubmed]
  5. Case report: ranitidine-induced bradycardia in a patient with dextrocardia. Yang, J., Russell, D.A., Bourdeau, J.E. Am. J. Med. Sci. (1996) [Pubmed]
  6. The crossover lung segment: congenital malformation associated with a variant of scimitar syndrome. Clements, B.S., Warner, J.O. Thorax (1987) [Pubmed]
  7. Partial anomalous pulmonary venous drainage associated with 45,X Turner's syndrome. Moore, J.W., Kirby, W.C., Rogers, W.M., Poth, M.A. Pediatrics (1990) [Pubmed]
  8. Diagnosis and outcome of dextrocardia diagnosed in the fetus. Walmsley, R., Hishitani, T., Sandor, G.G., Lim, K., Duncan, W., Tessier, F., Farquharson, D.F., Potts, J.E. Am. J. Cardiol. (2004) [Pubmed]
  9. Gadolinium-enhanced MR angiography in the evaluation of congenital cardiovascular disease pre- and postoperative states in infants and children. Masui, T., Katayama, M., Kobayashi, S., Ito, T., Seguchi, M., Koide, M., Nozaki, A., Sakahara, H. Journal of magnetic resonance imaging : JMRI. (2000) [Pubmed]
  10. Scimitar syndrome with pulmonary arteriovenous fistulas. Le Rochais, J.P., Icard, P., Davani, S., Abouz, D., Evrard, C. Ann. Thorac. Surg. (1999) [Pubmed]
  11. Multiple congenital abnormalities identifiable on 99Tcm HIDA scan. Peters, A.M., Gordon, I. Clinical radiology. (1989) [Pubmed]
  12. The prostaglandin challenge. Test to unmask obstructed total anomalous pulmonary venous connections in asplenia syndrome. Freedom, R.M., Olley, P.M., Coceani, F., Rowe, R.D. British heart journal. (1978) [Pubmed]
  13. Fetal diagnosis of atrioventricular septal defect with dextrocardia in trisomy 18. Pauliks, L.B., Friedman, D.M., Flynn, P.A. Journal of perinatal medicine. (2000) [Pubmed]
  14. Phenotypes with GATA4 or NKX2.5 mutations in familial atrial septal defect. Hirayama-Yamada, K., Kamisago, M., Akimoto, K., Aotsuka, H., Nakamura, Y., Tomita, H., Furutani, M., Imamura, S., Takao, A., Nakazawa, M., Matsuoka, R. Am. J. Med. Genet. A (2005) [Pubmed]
  15. Major congenital malformations presenting in the first 24 hours of life in 3865 consecutive births in south of Beirut. Incidence and pattern. Bittar, Z. Le Journal médical libanais. The Lebanese medical journal. (1998) [Pubmed]
  16. Isolated left superior vena cava to the left atrium with situs solitus and dextrocardia: extracardiac repair facilitated by juxtaposition of the atrial appendages. McElhinney, D.B., Mishaly, D.A., Moore, P., Brook, M.M., Reddy, V.M., Hanley, F.L. Am. J. Cardiol. (1997) [Pubmed]
  17. Transposition of the great arteries, primum atrial septal defect, azygos continuation of the inferior vena cava, bilateral superior venae cavae and dextrocardia with centrally placed liver. Jacob, T., Ablett, M., Stark, J. Am. Heart J. (1977) [Pubmed]
  18. An easy and safe technique for ventricular septal defect closure in hearts with atrioventricular discordant connection and dextrocardia. Fox, L.S. Ann. Thorac. Surg. (1987) [Pubmed]
  19. Heterotaxia in a fetus with campomelia, cervical lymphocele, polysplenia, and multicystic dysplastic kidneys: expanding the phenotype of Cumming syndrome. Ming, J.E., McDonald-McGinn, D.M., Markowitz, R.I., Ruchelli, E., Zackai, E.H. Am. J. Med. Genet. (1997) [Pubmed]
  20. Fetal dextrocardia: diagnosis and outcome in two tertiary centres. Bernasconi, A., Azancot, A., Simpson, J.M., Jones, A., Sharland, G.K. Heart (2005) [Pubmed]
  21. The optimal Fontan connection: a growing extracardiac lateral tunnel with pedicled pericardium. Gundry, S.R., Razzouk, A.J., del Rio, M.J., Shirali, G., Bailey, L.L. J. Thorac. Cardiovasc. Surg. (1997) [Pubmed]
  22. Growth hormone deficiency, wormian bones, dextrocardia, brachycamptodactyly, and other midline defects. Stratton, R.F., Parker, M.W. Am. J. Med. Genet. (1989) [Pubmed]
  23. Systemic lupus erythematosus and dextrocardia. Martínez-Cordero, E., Aracena-Taborga, G., López-Zepeda, J. Clinical and experimental rheumatology. (1990) [Pubmed]
  24. Familial dextrocardia, divergent strabismus and situs inversus of optic disc. Fishman, J.E., Spaier, A.H., Cohen, M.M. Am. J. Med. Sci. (1976) [Pubmed]
  25. Congenital diaphragmatic hernia "occulta". Sharma, D., Saxena, A., Raina, V.K. Indian journal of pediatrics. (2000) [Pubmed]
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