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Chemical Compound Review

Urovist     3,5-diacetamido-2,4,6- triiodo-benzoic...

Synonyms: Unipaque, Renocal, Renografin, ioxeol, Angiografin, ...
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Disease relevance of Angiografin


High impact information on Angiografin


Chemical compound and disease context of Angiografin


Biological context of Angiografin

  • Complementation analysis confirmed that the comG ORF1 protein is required for the ability of competent cultures to resolve into two populations with different cell densities on Renografin (E. R. Squibb & Sons, Princeton, N.J.) gradients, as well as for full expression of comE, another late competence locus [15].
  • Undiluted methylene blue and Renografin severely depressed sperm motility to 1.1%+/-0.5% and 2.3%+/-0.7%, respectively (P <0.05) [16].
  • Comparison of the magnitude of the reduction of FF induced by a 2-mL/kg IV dose of Renografin in the present immature rabbits with previous results in mature rabbits shows a surprising similarity (P = .33), despite lower resting BP, RBF, and glomerular filtration rate, as well as reduced tubular function in the immature animals [17].
  • RESULTS: Peritoneal lymphocyte proliferation and macrophage phagocytosis were significantly inhibited by renografin, ethiodol, methylene blue, and indigo carmine in a dose-dependent manner [18].
  • We have characterized selected populations of fibrosarcoma cells separated on density gradients of Renografin with respect to distribution in the cell cycle, clonogenic ability, and response to radiation [19].

Anatomical context of Angiografin


Associations of Angiografin with other chemical compounds


Gene context of Angiografin

  • The purified NS protein was assayed in a standard transcription system in combination with purified L protein and purified template (pellet fraction) prepared by renografin or CsCl banding [29].
  • The organisms were grown in mouse L cells and in the yolk sacs of chicken embryos, purified by Renografin density gradient centrifugation, and ruptured in a French pressure cell [30].
  • Total particle production was markedly reduced in cells infected with virus preparations containing DI particles and quantification of major cell-associated EHV-1 capsid species by electron microscopy and analysis in Renografin density gradients indicated that this reduction occurred at the level of capsid assembly [31].
  • Contrast media tonicity. Part II. Isotonic ioxaglate vs. standard renografin for IV-DSA evaluation of the carotid bifurcation, a double-blind prospective clinical trial [32].
  • The effect of the addition of radiographic contrast material (Renografin) to blood on the oxyhemoglobin dissociation curve and P50 was measured by a metabolic deoxygenation technique in a strongly buffered red cell suspension [33].

Analytical, diagnostic and therapeutic context of Angiografin


  1. Energy metabolism of monocytic Ehrlichia. Weiss, E., Williams, J.C., Dasch, G.A., Kang, Y.H. Proc. Natl. Acad. Sci. U.S.A. (1989) [Pubmed]
  2. Single film retrograde umbilical aortography in the diagnosis of hypoplastic left heart syndrome with aortic atresia. Rosengart, R., Jarmakani, J.M., Emmanouilides, G.C. Circulation (1976) [Pubmed]
  3. Kinetic heterogeneity in density-separated murine fibrosarcoma subpopulations. Brock, W.A., Swartzendruber, D.E., Grdina, D.J. Cancer Res. (1982) [Pubmed]
  4. Further characterization of the replicative complex of vesicular stomatitis virus. Simonsen, C.C., Hill, V.M., Summers, D.F. J. Virol. (1979) [Pubmed]
  5. Contrast ultrasonography of the kidney: a new method for evaluation of renal perfusion in vivo. Lang, R.M., Feinstein, S.B., Powsner, S.M., McCoy, C.E., Frederickson, E.D., Neumann, A., Goldberg, L.I., Borow, K.M. Circulation (1987) [Pubmed]
  6. Reflex vasodilation induced by coronary angiography in human subjects. Zelis, R., Caudill, C.C., Baggette, K., Mason, D.T. Circulation (1976) [Pubmed]
  7. Chitin synthetase zymogen is attached to the yeast plasma membrane. Durán, A., Bowers, B., Cabib, E. Proc. Natl. Acad. Sci. U.S.A. (1975) [Pubmed]
  8. Direct evidence for ligand-induced internalization of the yeast alpha-factor pheromone receptor. Schandel, K.A., Jenness, D.D. Mol. Cell. Biol. (1994) [Pubmed]
  9. Biosynthesis of the yeast cell wall. I. Preparation and properties of beta-(1 leads to 3)glucan synthetase. Shematek, E.M., Braatz, J.A., Cabib, E. J. Biol. Chem. (1980) [Pubmed]
  10. Isolation of coronavirus envelope glycoproteins and interaction with the viral nucleocapsid. Sturman, L.S., Holmes, K.V., Behnke, J. J. Virol. (1980) [Pubmed]
  11. Ventricular fibrillation from diatrizoate with and without chelating agents. Violante, M.R., Thomson, K.R., Fischer, H.W., Kenyon, T. Radiology. (1978) [Pubmed]
  12. Synthesis of DNA and protein by Anaplasma marginale in bovine erythrocytes during short-term culture. Davis, W.C., Talmadge, J.E., Parish, S.M., Johnson, M.I., Vibber, S.D. Infect. Immun. (1978) [Pubmed]
  13. Contractile, metabolic and arrhythmogenic effects of ionic and nonionic contrast agents in the isolated rat heart. Gloth, S.T., Gerstenblith, G., Brinker, J.A. Am. Heart J. (1992) [Pubmed]
  14. Contrast media-related complications during cardiac catheterization using Hexabrix or Renografin in high-risk patients. Feldman, R.L., Jalowiec, D.A., Hill, J.A., Lambert, C.R. Am. J. Cardiol. (1988) [Pubmed]
  15. Nucleotide sequence and genetic organization of the Bacillus subtilis comG operon. Albano, M., Breitling, R., Dubnau, D.A. J. Bacteriol. (1989) [Pubmed]
  16. Effect of methylene blue, indigo carmine, and Renografin on human sperm motility. Sheynkin, Y.R., Starr, C., Li, P.S., Goldstein, M. Urology (1999) [Pubmed]
  17. Contrast media and renal function in the immature kidney. Newman, B., Caldicott, W.J., Michelow, P. Investigative radiology. (1987) [Pubmed]
  18. Hysterosalpingography contrast media and chromotubation dye inhibit peritoneal lymphocyte and macrophage function in vitro: a potential mechanism for fertility enhancement. Goodman, S.B., Rein, M.S., Hill, J.A. Fertil. Steril. (1993) [Pubmed]
  19. Response of selected tumour cell populations separated from a fibrosarcoma following irradiation in situ with fast neutrons. Grdina, D.J., Linde, S., Mason, K. The British journal of radiology. (1978) [Pubmed]
  20. Computer methods for myocardial contrast two-dimensional echocardiography. Ong, K., Maurer, G., Feinstein, S., Zwehl, W., Meerbaum, S., Corday, E. J. Am. Coll. Cardiol. (1984) [Pubmed]
  21. The quantitative transplantation of subpopulations of rat mammary gland cells separated on renografin gradients. Gould, M.N., Clifton, K.H. Exp. Cell Res. (1978) [Pubmed]
  22. Separation of mouse testis cells by equilibrium density centrifugation in renografin gradients. Meistrich, M.L., Trostle, P.K. Exp. Cell Res. (1975) [Pubmed]
  23. In vitro stimulation of human peripheral blood lymphocytes by soluble and membrane fractions of renografin-purified typhus group rickettsiae. Bourgeois, A.L., Dasch, G.A., Strong, D.M. Infect. Immun. (1980) [Pubmed]
  24. Immunological and biological characterization of Coxiella burnetii, phases I and II, separated from host components. Williams, J.C., Peacock, M.G., McCaul, T.F. Infect. Immun. (1981) [Pubmed]
  25. Hyperemic response of intracoronary contrast agents during two-dimensional echographic delineation of regional myocardium. Kondo, S., Tei, C., Meerbaum, S., Corday, E., Shah, P.M. J. Am. Coll. Cardiol. (1984) [Pubmed]
  26. Bacteriophage conversion of spore-negative mutants to spore-positive in Bacillus pumilus. Bramucci, M.G., Keggins, K.M., Lovett, P.S. J. Virol. (1977) [Pubmed]
  27. Localization of the conduction delay occurring during coronary arteriography. Sostman, H.D., Simon, A.L., Langou, R.A. Investigative radiology. (1977) [Pubmed]
  28. A comparison of iohexol and diatrizoate-meglumine in children undergoing cardiac catheterization. Pelech, A.N., Allard, S.M., Hurd, R.T., Giddins, N.G., Collins, G.F. Investigative radiology. (1991) [Pubmed]
  29. Both NS and L proteins are required for in vitro RNA synthesis by vesicular stomatitis virus. Emerson, S.U., Yu, Y. J. Virol. (1975) [Pubmed]
  30. Enzymatic activities leading to pyrimidine nucleotide biosynthesis from cell-free extracts of Rickettsia typhi. Williams, J.C., Peterson, J.C. Infect. Immun. (1976) [Pubmed]
  31. Alterations in virus protein synthesis and capsid production in infection with DI particles of herpesvirus. Henry, B.E., Newcomb, W.W., O'Callaghan, D.J. J. Gen. Virol. (1980) [Pubmed]
  32. Contrast media tonicity. Part II. Isotonic ioxaglate vs. standard renografin for IV-DSA evaluation of the carotid bifurcation, a double-blind prospective clinical trial. Burbank, F.H., Bradley, B.R., Yegnashankaran, S., Enzmann, D.R. Investigative radiology. (1986) [Pubmed]
  33. Depression of intramyocardial oxyhemoglobin dissociation by angiographic contrast media. Sheps, D.S., Cameron, B.F., Mallon, S.M., Sommer, L.S., Lo, W.C., Harkness, D.R., Myerburg, R.J. Am. Heart J. (1980) [Pubmed]
  34. The effect of intracoronary injection of contrast medium upon coronary blood flow. Bassan, M., Ganz, W., Marcus, H.S., Swan, H.J. Circulation (1975) [Pubmed]
  35. Myocardial contrast echocardiography without significant hemodynamic effects or reactive hyperemia: a major advantage in the imaging of regional myocardial perfusion. Keller, M.W., Glasheen, W., Teja, K., Gear, A., Kaul, S. J. Am. Coll. Cardiol. (1988) [Pubmed]
  36. Functional and pathologic effects of multiple echocardiographic contrast injections on the myocardium, brain and kidney. Gillam, L.D., Kaul, S., Fallon, J.T., Levine, R.A., Hedley-Whyte, E.T., Guerrero, J.L., Weyman, A.E. J. Am. Coll. Cardiol. (1985) [Pubmed]
  37. Characterization of the Madrid E strain of Rickettsia prowazekii purified by renografin density gradient centrifugation. Dasch, G.A., Weiss, E. Infect. Immun. (1977) [Pubmed]
  38. Partial purification and characterization of the major species-specific protein antigens of Rickettsia typhi and Rickettsia prowazekii identified by rocket immunoelectrophoresis. Dasch, G.A., Samms, J.R., Williams, J.C. Infect. Immun. (1981) [Pubmed]
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