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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Social Environment

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Disease relevance of Social Environment


Psychiatry related information on Social Environment


High impact information on Social Environment

  • This study examines the prolactin response to fenfluramine hydrochloride challenge in young boys who show clinically significant aggressive behavior or who are raised in a social environment that is conducive to the development of chronic aggression [5].
  • We show that in non-human mammals the stability of the social environment in which the pregnant females live is critical for the offsprings' social and sexual behaviour later in life as well as for reproductive functioning, endocrine state and androgen and estrogen receptor distribution in specific parts of the brain [6].
  • The effects of age on the response to two doses of dexamethasone and two doses of CRF were assessed in females living in a stable social environment (control) and in socially stressed females removed from their group and housed temporarily in a remote, nonsocial environment (separated) [7].
  • The specific difference between autistic and MCDD children in their cortisol response to psychosocial stress indicates that the disturbed reactions to the social environment observed in these disorders may have different biological backgrounds [8].
  • Neither acceleration nor deceleration of puberty by varying the female's social environment had any effect on either body fat or leptin [9].

Biological context of Social Environment

  • Thus, it appears that PR deletion affects the display of sexual behavior and its modulation by dopamine, as well as the differentiation of dopaminergic cells and the plasticity of those cells in response to social environment and behavioral experience [10].

Anatomical context of Social Environment


Associations of Social Environment with chemical compounds


Gene context of Social Environment


  1. Differential effects of social isolation upon body weight, food consumption, and responsiveness to novel and social environment in bombesin receptor subtype-3 (BRS-3) deficient mice. Yamada, K., Ohki-Hamazaki, H., Wada, K. Physiol. Behav. (2000) [Pubmed]
  2. Social stress and state-to-state differences in smoking and smoking related mortality in the United States. Colby, J.P., Linsky, A.S., Straus, M.A. Social science & medicine (1982) (1994) [Pubmed]
  3. Housing influences exploration and social interaction of control and DSP-4-treated rats. Cornwell-Jones, C.A., Palfai, T., Krasenbaum, D., Byer, E., Clark, R., Kinnard, K. Physiol. Behav. (1992) [Pubmed]
  4. Social modulation of androgen levels in male teleost fish. Oliveira, R.F., Hirschenhauser, K., Carneiro, L.A., Canario, A.V. Comp. Biochem. Physiol. B, Biochem. Mol. Biol. (2002) [Pubmed]
  5. Neuroendocrine response to fenfluramine challenge in boys. Associations with aggressive behavior and adverse rearing. Pine, D.S., Coplan, J.D., Wasserman, G.A., Miller, L.S., Fried, J.E., Davies, M., Cooper, T.B., Greenhill, L., Shaffer, D., Parsons, B. Arch. Gen. Psychiatry (1997) [Pubmed]
  6. The effects of prenatal social stress on behaviour: mechanisms and function. Kaiser, S., Sachser, N. Neuroscience and biobehavioral reviews. (2005) [Pubmed]
  7. Activity of the hypothalamic-pituitary-adrenal axis is altered by aging and exposure to social stress in female rhesus monkeys. Gust, D.A., Wilson, M.E., Stocker, T., Conrad, S., Plotsky, P.M., Gordon, T.P. J. Clin. Endocrinol. Metab. (2000) [Pubmed]
  8. Differentiation between autism and multiple complex developmental disorder in response to psychosocial stress. Jansen, L.M., Gispen-de Wied, C.C., van der Gaag, R.J., van Engeland, H. Neuropsychopharmacology (2003) [Pubmed]
  9. Puberty in female mice is not associated with increases in either body fat or leptin. Bronson, F.H. Endocrinology (2001) [Pubmed]
  10. Genotype differences in behavior and tyrosine hydroxylase expression between wild-type and progesterone receptor knockout mice. Woolley, S.C., O'Malley, B., Lydon, J., Crews, D. Behav. Brain Res. (2006) [Pubmed]
  11. Season and social environment influence the membrane integrity of ejaculated boar spermatozoa as assessed by ouabain sensitivity. Trudeau, V., Sanford, L.M. Can. J. Physiol. Pharmacol. (1986) [Pubmed]
  12. The social environment and essential hypertension in mice: possible role of the innervation of the adrenal cortex. Henry, J.P., Stephens, P.M. Prog. Brain Res. (1977) [Pubmed]
  13. Role of epinephrine in acute stress. Wortsman, J. Endocrinol. Metab. Clin. North Am. (2002) [Pubmed]
  14. Chronic administration of the 5-HT3 receptor antagonist BRL 43694; effects on reflex epilepsy and social behaviour of the Mongolian gerbil. Cutler, M.G., Piper, D.C. Psychopharmacology (Berl.) (1990) [Pubmed]
  15. Differential effects of intraspecific interactions on the striatal dopamine system in social and non-social voles. Curtis, J.T., Stowe, J.R., Wang, Z. Neuroscience (2003) [Pubmed]
  16. DSP-4 treatment influences olfactory preferences of developing rats. Cornwell, C.A., Chang, J.W., Cole, B., Fukada, Y., Gianulli, T., Rathbone, E.A., McFarlane, H., McGaugh, J.L. Brain Res. (1996) [Pubmed]
  17. Plasma concentrations of testosterone in the developing ram in different social environments. Illius, A.W., Haynes, N.B., Purvis, K., Lamming, G.E. J. Reprod. Fertil. (1976) [Pubmed]
  18. Occupational lead exposure and screening of glucose-6-phosphate dehydrogenase polymorphism: useful prevention or nonvoluntary discrimination? Cocco, P. International archives of occupational and environmental health. (1998) [Pubmed]
  19. Integrated multimodal therapy of children with attention-deficit hyperactivity disorder. Nathan, W.A. Bulletin of the Menninger Clinic. (1992) [Pubmed]
  20. Family environment of adolescents and coping in the hospital. Steiner, H., Levine, S. Psychoneuroendocrinology (1988) [Pubmed]
  21. Tyrosine hydroxylase expression is affected by sexual vigor and social environment in male Cnemidophorus inornatus. Woolley, S.C., Sakata, J.T., Crews, D. J. Comp. Neurol. (2004) [Pubmed]
  22. Psychosocial influences on immune responses to HSV-1 infection in BALB/c mice. Karp, J.D., Moynihan, J.A., Ader, R. Brain Behav. Immun. (1997) [Pubmed]
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