Gene Review:
Brs3 - bombesin-like receptor 3
Mus musculus
Synonyms:
BRS-3, Bombesin receptor subtype-3
Wada,
Ohki-Hamazaki,
Apaya,
Wada,
Arai,
Mitchell,
Wada,
Usui,
Wada,
Wada,
Ohki-Hamazaki,
Sakaki,
Yamada,
Ueno,
Wada,
Humphries,
Imaki,
Wada,
Showell,
Shimada,
Yamada,
Iijima,
Boyle,
Yamada,
Ellen E. Ladenheim,
Nahketah L. Hamilton,
Robert R. Behles,
Sheng Bi,
Lori L. Hampton,
James F. Battey,
Timothy H. Moran,
- Leptin resistance and enhancement of feeding facilitation by melanin-concentrating hormone in mice lacking bombesin receptor subtype-3. Maekawa, F., Quah, H.M., Tanaka, K., Ohki-Hamazaki, H. Diabetes (2004)
- The presence of receptors for bombesin/GRP and mRNA for three receptor subtypes in human ovarian epithelial cancers. Sun, B., Schally, A.V., Halmos, G. Regul. Pept. (2000)
- Mice lacking bombesin receptor subtype-3 develop metabolic defects and obesity. Ohki-Hamazaki, H., Watase, K., Yamamoto, K., Ogura, H., Yamano, M., Yamada, K., Maeno, H., Imaki, J., Kikuyama, S., Wada, E., Wada, K. Nature (1997)
- Structure and chromosomal localization of the mouse bombesin receptor subtype 3 gene. Weber, H.C., Hampton, L.L., Jensen, R.T., Battey, J.F. Gene (1998)
- Pharmacology and intracellular signaling mechanisms of the native human orphan receptor BRS-3 in lung cancer cells. Ryan, R.R., Weber, H.C., Mantey, S.A., Hou, W., Hilburger, M.E., Pradhan, T.K., Coy, D.H., Jensen, R.T. J. Pharmacol. Exp. Ther. (1998)
- Factors contributing to obesity in bombesin receptor subtype-3-deficient mice. Ladenheim, E.E., Hamilton, N.L., Behles, R.R., Bi, S., Hampton, L.L., Battey, J.F., Moran, T.H. Endocrinology (2008)
- Functional properties of two bombesin-like peptide receptors revealed by the analysis of mice lacking neuromedin B receptor. Ohki-Hamazaki, H., Sakai, Y., Kamata, K., Ogura, H., Okuyama, S., Watase, K., Yamada, K., Wada, K. J. Neurosci. (1999)
- The bombesin receptor subtypes have distinct G protein specificities. Jian, X., Sainz, E., Clark, W.A., Jensen, R.T., Battey, J.F., Northup, J.K. J. Biol. Chem. (1999)
- Bombesin-like peptide receptor gene expression, regulation, and function in fetal murine lung. Shan, L., Emanuel, R.L., Dewald, D., Torday, J.S., Asokanathan, N., Wada, K., Wada, E., Sunday, M.E. Am. J. Physiol. Lung Cell Mol. Physiol. (2004)
- Bombesin-like peptides and mast cell responses: relevance to bronchopulmonary dysplasia? Subramaniam, M., Sugiyama, K., Coy, D.H., Kong, Y., Miller, Y.E., Weller, P.F., Wada, K., Wada, E., Sunday, M.E. Am. J. Respir. Crit. Care Med. (2003)
- Molecular organization of the mouse gastrin-releasing peptide receptor gene and its promoter. Weber, H.C., Jensen, R.T., Battey, J.F. Gene (2000)
- Bombesin-like peptides: studies on food intake and social behaviour with receptor knock-out mice. Yamada, K., Wada, E., Wada, K. Ann. Med. (2000)
- Cloning and expression of the neuromedin B receptor and the third subtype of bombesin receptor genes in the mouse. Ohki-Hamazaki, H., Wada, E., Matsui, K., Wada, K. Brain Res. (1997)
- Discovery of high affinity bombesin receptor subtype 3 agonists. Wu, J.M., Nitecki, D.E., Biancalana, S., Feldman, R.I. Mol. Pharmacol. (1996)
- In vivo inhibition of PC-3 human androgen-independent prostate cancer by a targeted cytotoxic bombesin analogue, AN-215. Plonowski, A., Nagy, A., Schally, A.V., Sun, B., Groot, K., Halmos, G. Int. J. Cancer (2000)
- Bombesin inhibits alveolarization and promotes pulmonary fibrosis in newborn mice. Ashour, K., Shan, L., Lee, J.H., Schlicher, W., Wada, K., Wada, E., Sunday, M.E. Am. J. Respir. Crit. Care Med. (2006)
- Hyperresponsiveness to palatable and aversive taste stimuli in genetically obese (bombesin receptor subtype-3-deficient) mice. Yamada, K., Wada, E., Imaki, J., Ohki-Hamazaki, H., Wada, K. Physiol. Behav. (1999)
- The design of a new potent and selective ligand for the orphan bombesin receptor subtype 3 (BRS3). Boyle, R.G., Humphries, J., Mitchell, T., Showell, G.A., Apaya, R., Iijima, H., Shimada, H., Arai, T., Ueno, H., Usui, Y., Sakaki, T., Wada, E., Wada, K. J. Pept. Sci. (2005)
- Identification of key amino acids in the gastrin-releasing peptide receptor (GRPR) responsible for high affinity binding of gastrin-releasing peptide (GRP). Nakagawa, T., Hocart, S.J., Schumann, M., Tapia, J.A., Mantey, S.A., Coy, D.H., Tokita, K., Katsuno, T., Jensen, R.T. Biochem. Pharmacol. (2005)
- Targeted cytotoxic analogue of bombesin/gastrin-releasing peptide inhibits the growth of H-69 human small-cell lung carcinoma in nude mice. Kiaris, H., Schally, A.V., Nagy, A., Sun, B., Armatis, P., Szepeshazi, K. Br. J. Cancer (1999)
- Differential effects of social isolation upon body weight, food consumption, and responsiveness to novel and social environment in bombesin receptor subtype-3 (BRS-3) deficient mice. Yamada, K., Ohki-Hamazaki, H., Wada, K. Physiol. Behav. (2000)
- Molecular cloning, genomic organization and selective expression of bombesin receptor subtype 3 in the sheep hypothalamus and pituitary. Whitley, J.C., Moore, C., Giraud, A.S., Shulkes, A. J. Mol. Endocrinol. (1999)
- Mutation in bombesin receptor subtype-3 gene is not a major cause of obesity in the Japanese. Hotta, K., Matsukawa, Y., Nishida, M., Kotani, K., Takahashi, M., Kuriyama, H., Nakamura, T., Wada, K., Yamashita, S., Funahashi, T., Matsuzawa, Y. Horm. Metab. Res. (2000)