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MeSH Review

Sexual Behavior

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Disease relevance of Sexual Behavior


Psychiatry related information on Sexual Behavior


High impact information on Sexual Behavior

  • Parent-of-origin influences on social cognition in Turner syndrome might be due to the presence of imprinted genes on the X. Imprinting of X-linked genes has also been implicated in the male prevalence of autistic spectrum disorders, in male sexual orientation and in the developmental delay of XO mouse embryos [11].
  • Despite an appreciable placebo response, the higher testosterone dose resulted in further increases in scores for frequency of sexual activity and pleasure-orgasm in the Brief index of Sexual Functioning for Women (P=0.03 for both comparisons with placebo) [12].
  • Selective inhibition of pituitary-gonadal function with a long-acting agonist analogue of gonadotropin-releasing hormone may abolish the deviant sexual behavior by reducing testosterone secretion [6].
  • At each visit, we collected information about lifestyle and sexual behavior and obtained cervicovaginal-lavage samples for the detection of HPV DNA by polymerase chain reaction and Southern blot hybridization [13].
  • Our results corroborate the previously reported linkage between Xq28 and male homosexuality in selected kinships and suggest that this region contains a locus that influences individual variations in sexual orientation in men but not in women [14].

Chemical compound and disease context of Sexual Behavior


Biological context of Sexual Behavior


Anatomical context of Sexual Behavior


Associations of Sexual Behavior with chemical compounds


Gene context of Sexual Behavior


Analytical, diagnostic and therapeutic context of Sexual Behavior


  1. Mice lacking progesterone receptor exhibit pleiotropic reproductive abnormalities. Lydon, J.P., DeMayo, F.J., Funk, C.R., Mani, S.K., Hughes, A.R., Montgomery, C.A., Shyamala, G., Conneely, O.M., O'Malley, B.W. Genes Dev. (1995) [Pubmed]
  2. Genome-wide prediction of imprinted murine genes. Luedi, P.P., Hartemink, A.J., Jirtle, R.L. Genome Res. (2005) [Pubmed]
  3. The role of neurosteroids and non-genomic effects of progestins and androgens in mediating sexual receptivity of rodents. Frye, C.A. Brain Res. Brain Res. Rev. (2001) [Pubmed]
  4. Young people's sexual health in South Africa: HIV prevalence and sexual behaviors from a nationally representative household survey. Pettifor, A.E., Rees, H.V., Kleinschmidt, I., Steffenson, A.E., MacPhail, C., Hlongwa-Madikizela, L., Vermaak, K., Padian, N.S. AIDS (2005) [Pubmed]
  5. Sex and the patient with cardiovascular risk factors: focus on sildenafil. Kloner, R.A. Am. J. Med. (2000) [Pubmed]
  6. Treatment of men with paraphilia with a long-acting analogue of gonadotropin-releasing hormone. Rösler, A., Witztum, E. N. Engl. J. Med. (1998) [Pubmed]
  7. Classical conditioning: induction of luteinizing hormone and testosterone secretion in anticipation of sexual activity. Graham, J.M., Desjardins, C. Science (1980) [Pubmed]
  8. Continuous or intermittent dosing with sertraline for patients with severe premenstrual syndrome or premenstrual dysphoric disorder. Freeman, E.W., Rickels, K., Sondheimer, S.J., Polansky, M., Xiao, S. The American journal of psychiatry. (2004) [Pubmed]
  9. Severe adverse life events and depressive symptoms among women with, or at risk for, HIV infection in four cities in the United States of America. Moore, J., Schuman, P., Schoenbaum, E., Boland, B., Solomon, L., Smith, D. AIDS (1999) [Pubmed]
  10. Male-to-female transsexuals have female neuron numbers in a limbic nucleus. Kruijver, F.P., Zhou, J.N., Pool, C.W., Hofman, M.A., Gooren, L.J., Swaab, D.F. J. Clin. Endocrinol. Metab. (2000) [Pubmed]
  11. Identification of a cluster of X-linked imprinted genes in mice. Raefski, A.S., O'Neill, M.J. Nat. Genet. (2005) [Pubmed]
  12. Transdermal testosterone treatment in women with impaired sexual function after oophorectomy. Shifren, J.L., Braunstein, G.D., Simon, J.A., Casson, P.R., Buster, J.E., Redmond, G.P., Burki, R.E., Ginsburg, E.S., Rosen, R.C., Leiblum, S.R., Caramelli, K.E., Mazer, N.A. N. Engl. J. Med. (2000) [Pubmed]
  13. Natural history of cervicovaginal papillomavirus infection in young women. Ho, G.Y., Bierman, R., Beardsley, L., Chang, C.J., Burk, R.D. N. Engl. J. Med. (1998) [Pubmed]
  14. Linkage between sexual orientation and chromosome Xq28 in males but not in females. Hu, S., Pattatucci, A.M., Patterson, C., Li, L., Fulker, D.W., Cherny, S.S., Kruglyak, L., Hamer, D.H. Nat. Genet. (1995) [Pubmed]
  15. Haploinsufficiency of cytochrome P450 17alpha-hydroxylase/17,20 lyase (CYP17) causes infertility in male mice. Liu, Y., Yao, Z.X., Bendavid, C., Borgmeyer, C., Han, Z., Cavalli, L.R., Chan, W.Y., Folmer, J., Zirkin, B.R., Haddad, B.R., Gallicano, G.I., Papadopoulos, V. Mol. Endocrinol. (2005) [Pubmed]
  16. The 26S proteasome participates in the sequential inhibition of estrous behavior induced by progesterone in rats. González-Flores, O., Guerra-Araiza, C., Cerbón, M., Camacho-Arroyo, I., Etgen, A.M. Endocrinology (2004) [Pubmed]
  17. Neonatal antidepressant exposure has lasting effects on behavior and serotonin circuitry. Maciag, D., Simpson, K.L., Coppinger, D., Lu, Y., Wang, Y., Lin, R.C., Paul, I.A. Neuropsychopharmacology (2006) [Pubmed]
  18. Exposure to genistein during gestation and lactation demasculinizes the reproductive system in rats. Wisniewski, A.B., Klein, S.L., Lakshmanan, Y., Gearhart, J.P. J. Urol. (2003) [Pubmed]
  19. Differential effects of the serotonin1A agonist, 8-OH-DPAT, on masculine and feminine sexual behavior of the ferret. Paredes, R.G., Kica, E., Baum, M.J. Psychopharmacology (Berl.) (1994) [Pubmed]
  20. Environmental-like exposure to low levels of estrogen affects sexual behavior and physiology of female rats. Della Seta, D., Farabollini, F., Dessì-Fulgheri, F., Fusani, L. Endocrinology (2008) [Pubmed]
  21. Convergent pathways for steroid hormone- and neurotransmitter-induced rat sexual behavior. Mani, S.K., Allen, J.M., Clark, J.H., Blaustein, J.D., O'Malley, B.W. Science (1994) [Pubmed]
  22. Neuroendocrinology of song behavior and avian brain plasticity: multiple sites of action of sex steroid hormones. Ball, G.F., Riters, L.V., Balthazart, J. Frontiers in neuroendocrinology. (2002) [Pubmed]
  23. Regulation of anxiety and initiation of sexual behavior by CREB in the nucleus accumbens. Barrot, M., Wallace, D.L., Bolaños, C.A., Graham, D.L., Perrotti, L.I., Neve, R.L., Chambliss, H., Yin, J.C., Nestler, E.J. Proc. Natl. Acad. Sci. U.S.A. (2005) [Pubmed]
  24. Functional testicular tissue does not masculinize development of the zebra finch song system. Wade, J., Arnold, A.P. Proc. Natl. Acad. Sci. U.S.A. (1996) [Pubmed]
  25. Sexual orientation in Drosophila is altered by the satori mutation in the sex-determination gene fruitless that encodes a zinc finger protein with a BTB domain. Ito, H., Fujitani, K., Usui, K., Shimizu-Nishikawa, K., Tanaka, S., Yamamoto, D. Proc. Natl. Acad. Sci. U.S.A. (1996) [Pubmed]
  26. Reduction of lipocalin-type prostaglandin D synthase in the preoptic area of female mice mimics estradiol effects on arousal and sex behavior. Mong, J.A., Devidze, N., Goodwillie, A., Pfaff, D.W. Proc. Natl. Acad. Sci. U.S.A. (2003) [Pubmed]
  27. Nitric oxide mediates sexual behavior in female rats. Mani, S.K., Allen, J.M., Rettori, V., McCann, S.M., O'Malley, B.W., Clark, J.H. Proc. Natl. Acad. Sci. U.S.A. (1994) [Pubmed]
  28. Sexual behavior and aggression in male mice: involvement of the vomeronasal system. Clancy, A.N., Coquelin, A., Macrides, F., Gorski, R.A., Noble, E.P. J. Neurosci. (1984) [Pubmed]
  29. Functional conservation of the fruitless male sex-determination gene across 250 Myr of insect evolution. Gailey, D.A., Billeter, J.C., Liu, J.H., Bauzon, F., Allendorfer, J.B., Goodwin, S.F. Mol. Biol. Evol. (2006) [Pubmed]
  30. Estrogen and spermatogenesis. O'Donnell, L., Robertson, K.M., Jones, M.E., Simpson, E.R. Endocr. Rev. (2001) [Pubmed]
  31. Steroid hormone--and neurotransmitter-induced rat sexual behavior: addendum. Mani, S.K., Allen, J.M., Clark, J.H., Blaustein, J.D., O'Malley, B.W. Science (1995) [Pubmed]
  32. Androgen concentration in motor neurons of cranial nerves and spinal cord. Sar, M., Stumpf, W.E. Science (1977) [Pubmed]
  33. Perinatal dopamine-related drugs demasculinize rats. Hull, E.M., Nishita, J.K., Bitran, D., Dalterio, S. Science (1984) [Pubmed]
  34. Survival of reproductive behaviors in estrogen receptor beta gene-deficient (betaERKO) male and female mice. Ogawa, S., Chan, J., Chester, A.E., Gustafsson, J.A., Korach, K.S., Pfaff, D.W. Proc. Natl. Acad. Sci. U.S.A. (1999) [Pubmed]
  35. dissatisfaction, a gene involved in sex-specific behavior and neural development of Drosophila melanogaster. Finley, K.D., Taylor, B.J., Milstein, M., McKeown, M. Proc. Natl. Acad. Sci. U.S.A. (1997) [Pubmed]
  36. Acute disruption of select steroid receptor coactivators prevents reproductive behavior in rats and unmasks genetic adaptation in knockout mice. Apostolakis, E.M., Ramamurphy, M., Zhou, D., Oñate, S., O'Malley, B.W. Mol. Endocrinol. (2002) [Pubmed]
  37. Anatomical localization of the effects of 17 beta-estradiol on oxytocin receptor binding in the ventromedial hypothalamic nucleus. Johnson, A.E., Coirini, H., Ball, G.F., McEwen, B.S. Endocrinology (1989) [Pubmed]
  38. HIV, syphilis and heterosexual bridging among Peruvian men who have sex with men. Tabet, S., Sanchez, J., Lama, J., Goicochea, P., Campos, P., Rouillon, M., Cairo, J.L., Ueda, L., Watts, D., Celum, C., Holmes, K.K. AIDS (2002) [Pubmed]
  39. The effects of exogenous testosterone on sexuality and mood of normal men. Anderson, R.A., Bancroft, J., Wu, F.C. J. Clin. Endocrinol. Metab. (1992) [Pubmed]
  40. Nefazodone and the treatment of nonparaphilic compulsive sexual behavior: a retrospective study. Coleman, E., Gratzer, T., Nesvacil, L., Raymond, N.C. The Journal of clinical psychiatry. (2000) [Pubmed]
  41. Gonadotropin-releasing hormone II stimulates female sexual behavior in marmoset monkeys. Barnett, D.K., Bunnell, T.M., Millar, R.P., Abbott, D.H. Endocrinology (2006) [Pubmed]
  42. Effect of a single dose of levodopa on sexual response in men and women. Both, S., Everaerd, W., Laan, E., Gooren, L. Neuropsychopharmacology (2005) [Pubmed]
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