The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review


Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Suppuration

  • CONCLUSIONS: In the hospital setting, oral ciprofloxacin is as effective as the intravenous regimen in the initial empirical management of serious UTIs, including bacteremic forms, in patients without severe sepsis, obstruction, or renal foci of suppuration [1].
  • Pseudomonas aeruginosa (PA) infection is predominantly responsible for chronic lung suppuration in patients with CF, but its survival is critically dependent on the availability of extracellular iron, which it obtains via highly efficient mechanisms [2].
  • Experimental studies on dogs with staphylococcal osteomyelitis showed that it is possible to reduce florid bone suppuration by the use of hydroxyapatite granules containing an antibiotic or antiseptic [3].
  • Subjects were measured at baseline for plaque, gingivitis, BOP, suppuration, pocket depth and attachment level at 6 sites per tooth [4].
  • The subjects were examined clinically to determine the prevalence of periodontal pockets, gingival bleeding (BOP) and suppuration, and prevalence of keratotic oral mucosal lesions [5].

High impact information on Suppuration


Chemical compound and disease context of Suppuration

  • Clinical parameters such as probing depth, gingival redness, bleeding on probing and suppuration showed dramatic improvement at 12 months after clindamycin therapy [11].
  • While the frequency of sites with suppuration was markedly reduced following all treatments, it reached zero in the scaling plus tetracycline fiber group [12].
  • Combined antibiotic therapy with amoxycillin and gentamicin, commenced within 23 h of direct infection, prevented acute suppuration and subsequent scarring [13].
  • While the frequency of sites with suppuration was markedly reduced following all antimicrobial treatments, the most effective reductions were seen in the scaling plus tetracycline fiber group, followed by the minocycline group [14].
  • METHODS: Nine partially dentate individuals with titanium implants demonstrating a marginal bone loss of > or = three threads as compared to baseline measurements made from 1-year intra-oral radiographs, bleeding on probing, and/or suppuration from the peri-implant sulci were included in the study [15].

Biological context of Suppuration


Anatomical context of Suppuration


Gene context of Suppuration

  • The subjects received full mouth clinical assessment of pocket depth, attachment level, BOP, gingival redness, suppuration and plaque accumulation at baseline and 90 days [19].
  • The prevalence of > or = 4 mm deep pockets, gingival suppuration, and loss of crestal bone were statistically significantly lower (P = 0.003, P<0.001, and P<0.05, respectively) and salivary buffering capacity higher (P <0.05) in those who had quit smoking compared to current smokers; there was no difference in BOP [5].
  • Clinical assessments of plaque, redness, suppuration, BOP, pocket depth and attachment level were made at 6 sites per tooth [20].
  • METHOD: Clinical assessments of plaque, gingival redness, suppuration, bleeding on probing, pocket depth and attachment level were made prior to SRP and at 3, 6, 9, and 12 months post-therapy [21].
  • Subgingival plaque samples were obtained and probing depth (PD), loss of attachment (LOA), bleeding on probing (BOP), suppuration (SUPP) and plaque (DEP) were recorded pre-treatment, 1, 3 and 6 months post-treatment [22].

Analytical, diagnostic and therapeutic context of Suppuration

  • Clinical parameters (suppuration, modified plaque index - mPI, modified bleeding index - mBI, probing pocket depth - PPD, pseudopocket - DIM, mucosal recession - REC, probing attachment level - PAL) were recorded at baseline, as well as 6, 12, 24 and 36 months after treatment [23].


  1. Oral vs intravenous ciprofloxacin in the initial empirical management of severe pyelonephritis or complicated urinary tract infections: a prospective randomized clinical trial. Mombelli, G., Pezzoli, R., Pinoja-Lutz, G., Monotti, R., Marone, C., Franciolli, M. Arch. Intern. Med. (1999) [Pubmed]
  2. Iron deficiency in cystic fibrosis: relationship to lung disease severity and chronic Pseudomonas aeruginosa infection. Reid, D.W., Withers, N.J., Francis, L., Wilson, J.W., Kotsimbos, T.C. Chest (2002) [Pubmed]
  3. Experimental and preliminary clinical experience with absorbable calcium phosphate granules containing an antibiotic or antiseptic for the local treatment of osteomyelitis. Eitenmüller, J., Schmidt, K.H., Peters, G., Gellissen, G., Weltin, R., Reichmann, W. J. Hosp. Infect. (1985) [Pubmed]
  4. Differences in the subgingival microbiota of Swedish and USA subjects who were periodontally healthy or exhibited minimal periodontal disease. Haffajee, A.D., Japlit, M., Bogren, A., Kent, R.L., Goodson, J.M., Socransky, S.S. Journal of clinical periodontology. (2005) [Pubmed]
  5. The association between smoking cessation and periodontal status and salivary proteinase levels. Liede, K.E., Haukka, J.K., Hietanen, J.H., Mattila, M.H., Rönkä, H., Sorsa, T. J. Periodontol. (1999) [Pubmed]
  6. Donor-leukocyte imaging in granulocytopenic patients with suspected abscesses: concise communication. Anstall, H.B., Coleman, R.E. J. Nucl. Med. (1982) [Pubmed]
  7. Association between rheumatoid arthritis and chronic bronchial suppuration. Bamji, A., Cooke, N.T. Ann. Rheum. Dis. (1984) [Pubmed]
  8. A randomised controlled clinical trial of antibiotic impregnation of testosterone pellet implants to reduce extrusion rate. Kelleher, S., Conway, A.J., Handelsman, D.J. Eur. J. Endocrinol. (2002) [Pubmed]
  9. Treatment of Calmette-Guérin bacillus adenitis: a metaanalysis. Goraya, J.S., Virdi, V.S. Pediatr. Infect. Dis. J. (2001) [Pubmed]
  10. Clinical outcome of implants placed immediately after implant removal. Covani, U., Barone, A., Cornelini, R., Crespi, R. J. Periodontol. (2006) [Pubmed]
  11. Efficacy of clindamycin hydrochloride in refractory periodontitis. 12-month results. Gordon, J., Walker, C., Lamster, I., West, T., Socransky, S., Seiger, M., Fasciano, R. J. Periodontol. (1985) [Pubmed]
  12. Comparison of 3 periodontal local antibiotic therapies in persistent periodontal pockets. Radvar, M., Pourtaghi, N., Kinane, D.F. J. Periodontol. (1996) [Pubmed]
  13. Prevention of scarring in experimental pyelonephritis in the rat by early antibiotic therapy. Slotki, I.N., Asscher, A.W. Nephron (1982) [Pubmed]
  14. A six-month comparison of three periodontal local antimicrobial therapies in persistent periodontal pockets. Kinane, D.F., Radvar, M. J. Periodontol. (1999) [Pubmed]
  15. Five-year clinical, microbiological, and radiological outcome following treatment of peri-implantitis in man. Leonhardt, A., Dahlén, G., Renvert, S. J. Periodontol. (2003) [Pubmed]
  16. Comparative scintigraphic study of 99mTc ciprofloxacin pharmacokinetics after intravenous and lymphotropic administration in experimental pulmonary suppuration. Lishmanov, Y.B., Sazonova, S.I., Sokolovich, E.G., Chernov, V.I. Bull. Exp. Biol. Med. (2005) [Pubmed]
  17. Studies on improvement of pharmaceutical preparations prescribed in hospitals. IV. Dibekacin sulfate viscous solution for treatment of mouth and throat wounds. Namiki, N., Yokoyama, H., Moriya, K., Fukuda, M., Takashima, T., Uchida, Y., Yuasa, H., Kanaya, Y. Drug Des. Deliv. (1986) [Pubmed]
  18. Lacrimal gland abscess: two case reports. McNab, A.A. Australian and New Zealand journal of ophthalmology. (1999) [Pubmed]
  19. Systemic doxycycline administration in the treatment of periodontal infections (I). Effect on the subgingival microbiota. Feres, M., Haffajee, A.D., Goncalves, C., Allard, K.A., Som, S., Smith, C., Goodson, J.M., Socransky, S.S. Journal of clinical periodontology. (1999) [Pubmed]
  20. The effect of SRP on the clinical and microbiological parameters of periodontal diseases. Haffajee, A.D., Cugini, M.A., Dibart, S., Smith, C., Kent, R.L., Socransky, S.S. Journal of clinical periodontology. (1997) [Pubmed]
  21. The effect of scaling and root planing on the clinical and microbiological parameters of periodontal diseases: 12-month results. Cugini, M.A., Haffajee, A.D., Smith, C., Kent, R.L., Socransky, S.S. Journal of clinical periodontology. (2000) [Pubmed]
  22. Adjunctive effects to non-surgical periodontal therapy of systemic metronidazole and amoxycillin alone and combined. A placebo controlled study. Rooney, J., Wade, W.G., Sprague, S.V., Newcombe, R.G., Addy, M. Journal of clinical periodontology. (2002) [Pubmed]
  23. Therapy of peri-implantitis with resective surgery. A 3-year clinical trial on rough screw-shaped oral implants. Part I: clinical outcome. Romeo, E., Ghisolfi, M., Murgolo, N., Chiapasco, M., Lops, D., Vogel, G. Clinical oral implants research. (2005) [Pubmed]
WikiGenes - Universities