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MeSH Review

Periodontal Pocket

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Disease relevance of Periodontal Pocket


High impact information on Periodontal Pocket


Chemical compound and disease context of Periodontal Pocket

  • Effects of tetracycline on the streptococcal flora of periodontal pockets [11].
  • Our results indicate that glutathione, a readily available thiol source in periodontal pockets, is a suitable substrate for H(2)S production by this microorganism [2].
  • We propose that PAD, acting in concert with arginine-specific proteinases from P. gingivalis, promotes the growth of the pathogen in the periodontal pocket, initially by enhancing its survivability and then by assisting the organism in its circumvention of host humoral defenses [12].
  • This study demonstrates that, by embedding metronidazole in ethyl cellulose, it is possible to obtain sustained release of the drug within the periodontal pocket for three days [13].
  • The highest recovery was found on TSBV agar plates cultured in air-5% CO2 both for plaque samples from periodontal pockets and for pure cultures [14].

Biological context of Periodontal Pocket


Anatomical context of Periodontal Pocket


Gene context of Periodontal Pocket


Analytical, diagnostic and therapeutic context of Periodontal Pocket


  1. Neutrophil dysfunctions, IL-8, and soluble L-selectin plasma levels in rapidly progressive versus adult and localized juvenile periodontitis: variations according to disease severity and microbial flora. Gainet, J., Dang, P.M., Chollet-Martin, S., Brion, M., Sixou, M., Hakim, J., Gougerot-Pocidalo, M.A., Elbim, C. J. Immunol. (1999) [Pubmed]
  2. Role of glutathione metabolism of Treponema denticola in bacterial growth and virulence expression. Chu, L., Dong, Z., Xu, X., Cochran, D.L., Ebersole, J.L. Infect. Immun. (2002) [Pubmed]
  3. Biological and chemical characterization of lipopolysaccharide from Selenomonas spp. in human periodontal pockets. Kurimoto, T., Tachibana, C., Suzuki, M., Watanabe, T. Infect. Immun. (1986) [Pubmed]
  4. Development and mechanical characterization of bioadhesive semi-solid, polymeric systems containing tetracycline for the treatment of periodontal diseases. Jones, D.S., Woolfson, A.D., Djokic, J., Coulter, W.A. Pharm. Res. (1996) [Pubmed]
  5. Oxygen metabolism by Treponema denticola. Caldwell, C.E., Marquis, R.E. Oral Microbiol. Immunol. (1999) [Pubmed]
  6. Is periodontal disease mediated by salivary BAFF in Sjögren's syndrome? Pers, J.O., d'Arbonneau, F., Devauchelle-Pensec, V., Saraux, A., Pennec, Y.L., Youinou, P. Arthritis Rheum. (2005) [Pubmed]
  7. Relationship between periodontal disease and C-reactive protein among adults in the Atherosclerosis Risk in Communities study. Slade, G.D., Ghezzi, E.M., Heiss, G., Beck, J.D., Riche, E., Offenbacher, S. Arch. Intern. Med. (2003) [Pubmed]
  8. Expression patterns of E-cadherin, involucrin, and connexin gap junction proteins in the lining epithelia of inflamed gingiva. Ye, P., Chapple, C.C., Kumar, R.K., Hunter, N. J. Pathol. (2000) [Pubmed]
  9. Role for recombinant gamma-glutamyltransferase from Treponema denticola in glutathione metabolism. Chu, L., Xu, X., Dong, Z., Cappelli, D., Ebersole, J.L. Infect. Immun. (2003) [Pubmed]
  10. Binding and utilization of human transferrin by Prevotella nigrescens. Duchesne, P., Grenier, D., Mayrand, D. Infect. Immun. (1999) [Pubmed]
  11. Effects of tetracycline on the streptococcal flora of periodontal pockets. Hawley, R.J., Lee, L.N., LeBlanc, D.J. Antimicrob. Agents Chemother. (1980) [Pubmed]
  12. Purification, characterization, and sequence analysis of a potential virulence factor from Porphyromonas gingivalis, peptidylarginine deiminase. McGraw, W.T., Potempa, J., Farley, D., Travis, J. Infect. Immun. (1999) [Pubmed]
  13. Sustained release device containing metronidazole for periodontal use. Golomb, G., Friedman, M., Soskolne, A., Stabholz, A., Sela, M.N. J. Dent. Res. (1984) [Pubmed]
  14. Comparison of two selective media for Actinobacillus actinomycetemcomitans. Martijn van Steenbergen, T.J., van Winkelhoff, A.J., van der Mispel, L., van der Velden, U., Abbas, F., de Graaff, J. J. Clin. Microbiol. (1986) [Pubmed]
  15. Gingival fluid and serum in periodontal diseases. II. Evidence for cleavage of complement components C3, C3 proactivator (factor B) and C4 in gingival fluid. Schenkein, H.A., Genco, R.J. J. Periodontol. (1977) [Pubmed]
  16. Multiple restriction fragment length polymorphism genotypes of Porphyromonas gingivalis in single periodontal pockets. Zhang, Y.J., Yasui, S., Yoshimura, F., Ishikawa, I. Oral Microbiol. Immunol. (1995) [Pubmed]
  17. Concentration of metronidazole in periodontal pockets after application of a metronidazole 25% dental gel. Stoltze, K. Journal of clinical periodontology. (1992) [Pubmed]
  18. An investigation of bioadhesion for periodontal and oral mucosal drug delivery. Needleman, I.G., Smales, F.C., Martin, G.P. Journal of clinical periodontology. (1997) [Pubmed]
  19. Effects of combined topical metronidazole and mechanical treatment on the subgingival flora in deep periodontal pockets in cuspids and bicuspids. Hitzig, C., Fosse, T., Charbit, Y., Bitton, C., Hannoun, L. J. Periodontol. (1997) [Pubmed]
  20. Biochemical and clinical factors influencing oral malodor in periodontal patients. Yaegaki, K., Sanada, K. J. Periodontol. (1992) [Pubmed]
  21. Patterns of cytokeratin expression in the epithelia of inflamed human gingiva and periodontal pockets. Mackenzie, I.C., Gao, Z. J. Periodont. Res. (1993) [Pubmed]
  22. Plasminogen activating capacity in gingival fluid from deteriorating and stable periodontal pockets. Olofsson, A., Matsson, L., Kinnby, B. J. Periodont. Res. (2002) [Pubmed]
  23. Enhanced interleukin 1 beta, interleukin 6 and tumor necrosis factor alpha in gingival crevicular fluid from periodontal pockets of patients infected with human immunodeficiency virus 1. Baqui, A.A., Meiller, T.F., Jabra-Rizk, M.A., Zhang, M., Kelley, J.I., Falkler, W.A. Oral Microbiol. Immunol. (2000) [Pubmed]
  24. The rag locus of Porphyromonas gingivalis: a novel pathogenicity island. Curtis, M.A., Hanley, S.A., Aduse-Opoku, J. J. Periodont. Res. (1999) [Pubmed]
  25. Relative avidity of serum immunoglobulin G antibody for the fimbria antigen of Actinobacillus actinomycetemcomitans in patients with adult periodontitis. Saito, A., Hosaka, Y., Nakagawa, T., Yamada, S., Okuda, K. Infect. Immun. (1993) [Pubmed]
  26. Inhibition of periodontopathogen-derived proteolytic enzymes by a high-molecular-weight fraction isolated from cranberry. Bodet, C., Piché, M., Chandad, F., Grenier, D. J. Antimicrob. Chemother. (2006) [Pubmed]
  27. Tissue necrosis after subgingival irrigation with fluoride solution. Sjöström, S., Kalfas, S. Journal of clinical periodontology. (1999) [Pubmed]
  28. Immunoglobulin G response of periodontitis patients to Porphyromonas gingivalis capsular carbohydrate and lipopolysaccharide antigens. Sims, T.J., Schifferle, R.E., Ali, R.W., Skaug, N., Page, R.C. Oral Microbiol. Immunol. (2001) [Pubmed]
  29. Periodontal pocket treatment in beagle dogs using subgingival doxycycline from a biodegradable system. I. Initial clinical responses. Polson, A.M., Southard, G.L., Dunn, R.L., Yewey, G.L., Godowski, K.C., Polson, A.P., Fulfs, J.C., Laster, L. J. Periodontol. (1996) [Pubmed]
  30. Locally delivered minocycline microspheres for the treatment of periodontitis in smokers. Paquette, D., Oringer, R., Lessem, J., Offenbacher, S., Genco, R., Persson, G.R., Santucci, E.A., Williams, R.C. Journal of clinical periodontology. (2003) [Pubmed]
  31. Effect of a local germicide on the occurrence of bacteremia during subgingival scaling. Witzenberger, T., O'Leary, T.J., Gillette, W.B. J. Periodontol. (1982) [Pubmed]
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