Disease relevance of Drug Utilization

• A drug utilization observation study collected data on a total of 1800 patients given flavoxate (Spasuret 200) over 2 weeks for urge incontinence [1].
• CONCLUSIONS: Drug utilization data indicate that COX-2 inhibitors are frequently used first line for degenerative osteoarthritis in the absence of overt inflammation, without prior adequate trial of paracetamol and with disregard for the cautions and contraindications of these agents [2].

High impact information on Drug Utilization

• Data from an intensive observational drug utilization study were analyzed to determine whether patients who received the combination of fluoxetine and lithium had more and different adverse events as compared with those receiving fluoxetine alone [3].
• A drug utilization review of prescribing patterns for trazodone versus amitriptyline [4].
• Drug utilization review of celecoxib in Ontario [5].
• To examine sex differences in the treatment with the SSRI sertraline in routine treatment of depression, data from a 6-month prospective drug utilization observation study on 3,858 women and 1,594 men were analysed for gender differences [6].
• Impact of reference-based pricing for angiotensin-converting enzyme inhibitors on drug utilization [7].

Biological context of Drug Utilization

• Undesirable blood pressure changes under naturalistic treatment with moclobemide, a reversible MAO-A inhibitor--results of the drug utilization observation studies [8].
• 550 prescriptions of the indoor patients receiving antimicrobial drugs in the Departments of Internal Medicine, Surgery, Urology and Paediatrics were analysed for drug utilization studies [9].

Anatomical context of Drug Utilization

• Correlation of drug utilization data for trimethoprim in a defined population with patterns of resistance among bacteria causing urinary tract infections [10].

Associations of Drug Utilization with chemical compounds

• Drug utilization patterns and outcomes associated with in-hospital treatment with risperidone or olanzapine [11].
• OBJECTIVE: To determine the effectiveness of a drug utilization review (DUR) letter intervention sent only to physicians, sent only to pharmacists, or sent to both physicians and pharmacists in changing physician prescribing behavior for dipyridamole [12].
• Quality-monitoring of psychotropic drug therapy in post-marketing surveillance. Results of a drug utilization observation (DUO) study on moclobemide [13].
• Drug utilization reviews of oral quinolone, cephalosporin, and macrolide use in nonacute care: a systematic review [14].
• Drug utilization review of concomitant use of specific serotonin reuptake inhibitors or clomipramine with antianxiety/sleep medications [15].

Gene context of Drug Utilization

• The method of DDD (defined daily dose) was used to determine the drug utilization of NSAIDs and H2-blockers in two randomly chosen hospitals in Sofia during the last year period [16].
• First results of PEGASUS confirm that drug utilization during pregnancy is rather common-85% of women use at least one preparation [17].
• METHODS: A drug utilization study using WHO methodology [Anatomical-Therapeutic-Chemical classification/defined daily doses (ATC/DDD)] was made [18].
• Conclusions - Antiepileptic drug utilization increased during the study period, the increase probably caused by expanding use in areas other than epilepsy [19].
• CMS continues to monitor drug utilization and expenditures in all of its programs in order to ensure that care is rendered in a cost-effective manner that is beneficial to the patient [20].

Analytical, diagnostic and therapeutic context of Drug Utilization

• Using estimates of drug utilization based on a defined daily dose, hospitalization rates were 5.8 per 1000 PY (95% CI 4.4-7.6) for chlorpropamide, 16.0 per 1000 PY (95% CI 9.5-26.9) for glyburide, and 9.1 per 1000 PY (95% CI 6.9-11.9) for insulin [21].
• Total parenteral nutrition: a concurrent drug utilization review [22].

References