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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Genes, mos

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Disease relevance of Genes, mos


High impact information on Genes, mos


Biological context of Genes, mos


Anatomical context of Genes, mos

  • We describe the molecular identification of a gene, designated T1, whose expression in mouse NIH 3T3 cells is strongly induced by the Ha-ras(EJ) and v-mos oncogenes and by serum [16].
  • After acute infection of Swiss 3T3 cells with virus containing the v-mos oncogene, cells expressing high levels of v-Mos round up and detach from the monolayer (floating cells), while cells that remain attached express 10-fold lower levels of v-Mos and are transformed [17].

Associations of Genes, mos with chemical compounds


Gene context of Genes, mos


  1. Nucleoside triphosphate-dependent DNA-binding properties of mos protein. Seth, A., Priel, E., Vande Woude, G.F. Proc. Natl. Acad. Sci. U.S.A. (1987) [Pubmed]
  2. Cellular Moloney murine sarcoma (c-mos) sequences are hypermethylated and transcriptionally silent in normal and transformed rodent cells. Gattoni, S., Kirschmeier, P., Weinstein, I.B., Escobedo, J., Dina, D. Mol. Cell. Biol. (1982) [Pubmed]
  3. Oncogene mediated repression of glucocorticoid hormone response elements and glucocorticoid receptor levels. Jaggi, R., Höck, W., Ziemiecki, A., Klemenz, R., Friis, R., Groner, B. Cancer Res. (1989) [Pubmed]
  4. Paclitaxel-induced apoptosis is associated with expression and activation of c-Mos gene product in human ovarian carcinoma SKOV3 cells. Ling, Y.H., Yang, Y., Tornos, C., Singh, B., Perez-Soler, R. Cancer Res. (1998) [Pubmed]
  5. Nucleotide sequence of the transforming gene of m1 murine sarcoma virus. Brow, M.A., Sen, A., Sutcliffe, J.G. J. Virol. (1984) [Pubmed]
  6. Specific proteolysis of the c-mos proto-oncogene product by calpain on fertilization of Xenopus eggs. Watanabe, N., Vande Woude, G.F., Ikawa, Y., Sagata, N. Nature (1989) [Pubmed]
  7. Function of c-mos proto-oncogene product in meiotic maturation in Xenopus oocytes. Sagata, N., Oskarsson, M., Copeland, T., Brumbaugh, J., Vande Woude, G.F. Nature (1988) [Pubmed]
  8. Mos and the cell cycle: the molecular basis of the transformed phenotype. Yew, N., Strobel, M., Vande Woude, G.F. Curr. Opin. Genet. Dev. (1993) [Pubmed]
  9. Effects of the v-mos oncogene on Xenopus development: meiotic induction in oocytes and mitotic arrest in cleaving embryos. Freeman, R.S., Kanki, J.P., Ballantyne, S.M., Pickham, K.M., Donoghue, D.J. J. Cell Biol. (1990) [Pubmed]
  10. Elevated levels of a specific class of nuclear phosphoproteins in cells transformed with v-ras and v-mos oncogenes and by cotransfection with c-myc and polyoma middle T genes. Giancotti, V., Pani, B., D'Andrea, P., Berlingieri, M.T., Di Fiore, P.P., Fusco, A., Vecchio, G., Philp, R., Crane-Robinson, C., Nicolas, R.H. EMBO J. (1987) [Pubmed]
  11. Evidence for interaction between v-Mos and a p34cdc2 isoform, p35cdk. Bai, W., Singh, B., Yang, Y., Arlinghaus, R.B. Oncogene (1992) [Pubmed]
  12. Recombinational junctions of variants of Moloney murine sarcoma virus: generation and divergence of a mammalian transforming gene. Donoghue, D.J., Hunter, T. J. Virol. (1983) [Pubmed]
  13. Comparison of myeloproliferative sarcoma virus with Moloney murine sarcoma virus variants by nucleotide sequencing and heteroduplex analysis. Stacey, A., Arbuthnott, C., Kollek, R., Coggins, L., Ostertag, W. J. Virol. (1984) [Pubmed]
  14. Expression of the v-Mos oncogene in male meiotic germ cells of transgenic mice results in metaphase arrest. Rosenberg, M.P., Aversa, C.R., Wallace, R., Propst, F. Cell Growth Differ. (1995) [Pubmed]
  15. Identification of protein tyrosine phosphatase 1B and casein as substrates for 124-v-Mos. Proikas-Cezanne, T., Stabel, S., Riethmacher, D. BMC Biochem. (2002) [Pubmed]
  16. Serum- and oncoprotein-mediated induction of a gene with sequence similarity to the gene encoding carcinoembryonic antigen. Klemenz, R., Hoffmann, S., Werenskiold, A.K. Proc. Natl. Acad. Sci. U.S.A. (1989) [Pubmed]
  17. Similarities between somatic cells overexpressing the mos oncogene and oocytes during meiotic interphase. Fukasawa, K., Murakami, M.S., Blair, D.G., Kuriyama, R., Hunt, T., Fischinger, P., Vande Woude, G.F. Cell Growth Differ. (1994) [Pubmed]
  18. Biologically active mutants with deletions in the v-mos oncogene assayed with retroviral vectors. Bold, R.J., Donoghue, D.J. Mol. Cell. Biol. (1985) [Pubmed]
  19. The activation of the phosphotyrosine phosphatase eta (r-PTP eta) is responsible for the somatostatin inhibition of PC Cl3 thyroid cell proliferation. Florio, T., Arena, S., Thellung, S., Iuliano, R., Corsaro, A., Massa, A., Pattarozzi, A., Bajetto, A., Trapasso, F., Fusco, A., Schettini, G. Mol. Endocrinol. (2001) [Pubmed]
  20. Genomic structure of the cottontail rabbit (Shope) papillomavirus. Giri, I., Danos, O., Yaniv, M. Proc. Natl. Acad. Sci. U.S.A. (1985) [Pubmed]
  21. Deregulation of specific E2F complexes by the v-mos oncogene. Afshari, C.A., Rhodes, N., Paules, R.S., Mudryj, M. Oncogene (1997) [Pubmed]
  22. Influence of exogenous ras and p53 on P-glycoprotein function in immortalized rodent fibroblasts. Kopnin, B.P., Stromskaya, T.P., Kondratov, R.V., Ossovskaya, V.S., Pugacheva, E.N., Rybalkina, E.Y., Khokhlova, O.A., Chumakov, P.M. Oncol. Res. (1995) [Pubmed]
  23. Mos activates myogenic differentiation by promoting heterodimerization of MyoD and E12 proteins. Lenormand, J.L., Benayoun, B., Guillier, M., Vandromme, M., Leibovitch, M.P., Leibovitch, S.A. Mol. Cell. Biol. (1997) [Pubmed]
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