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MeSH Review

Intermittent Positive-Pressure Breathing

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Disease relevance of Intermittent Positive-Pressure Breathing


High impact information on Intermittent Positive-Pressure Breathing


Chemical compound and disease context of Intermittent Positive-Pressure Breathing


Biological context of Intermittent Positive-Pressure Breathing

  • 5 mg salbutamol nebulized with IPPB resulted in a significant increase in peak expiratory flow rate when given before or after either Rotacaps or salbutamol nebulized without IPPB, whereas neither the dry powder nor the nebulized drug without IPPB resulted in significant change when given after salbutamol nebulized with IPPB [11].
  • It was concluded that the use of IPPB to administer nebulized salbutamol in oxygen had no advantage over passive inhalation in the initial treatment of patients with severe acute asthma [12].

Associations of Intermittent Positive-Pressure Breathing with chemical compounds

  • Studies were performed on the 14 patients, each of whom was randomly assigned to one of two treatment groups: distilled water or racemic epinephrine (RE), both being nebulized and delivered by manual IPPB [13].
  • Double-blind comparison of metaproterenol and isoetharine-phenylephrine solutions in intermittent positive pressure breathing in bronchospastic conditions [14].
  • Aerosolized lidocaine, administered by IPPB, is a safe and effective topical anesthetic agent which may be useful for instrumentation of the upper airway [15].
  • Five minutes after IPPB, Pao2 decreased to 69.2 +/- 8 torr; alveolar-arterial Po2 difference, breathing 21% O2, increased significantly; and serum K+ concentration decreased significantly [16].
  • Serum levels were measured in 13 subjects who received gentamicin either by inspiratory intermittent positive pressure breathing (IPPB-I) or by tracheal instillation [17].

Gene context of Intermittent Positive-Pressure Breathing


Analytical, diagnostic and therapeutic context of Intermittent Positive-Pressure Breathing


  1. Corticosteroids and racemic epinephrine with IPPB in the treatment of croup. Bass, J.W., Bruhn, F.W., Merritt, W.T. J. Pediatr. (1980) [Pubmed]
  2. Comparative effects of pressure support ventilation and intermittent positive pressure breathing (IPPB) in non-intubated healthy subjects. Mancebo, J., Isabey, D., Lorino, H., Lofaso, F., Lemaire, F., Brochard, L. Eur. Respir. J. (1995) [Pubmed]
  3. The effect of artifical ventilation and dehydrobenzperidol on the development of early changes in the respiratory system in dogs with Mendelson's syndrome. Budych, W. Anaesthesia, resuscitation, and intensive therapy. (1975) [Pubmed]
  4. Bronchodilator effects of fenoterol and salbutamol administered by intermittent positive pressure breathing to patients with asthma or chronic obstructive bronchitis. Lahdensuo, A. Respiration; international review of thoracic diseases. (1984) [Pubmed]
  5. Liver blood flow and oxygen consumption during hypocapnia and IPPV in the greyhound. Hughes, R.L., Mathie, R.T., Fitch, W., Campbell, D. Journal of applied physiology: respiratory, environmental and exercise physiology. (1979) [Pubmed]
  6. Albuterol and isoproterenol in bronchial asthma. Efficacy and toxicity of drugs administered via intermittent positive pressure breathing. Light, R.W., Taylor, R.W., George, R.B. Arch. Intern. Med. (1979) [Pubmed]
  7. Pulmonary alveolar proteinosis: successful treatment with aerosolized trypsin. Jay, S.J. Am. J. Med. (1979) [Pubmed]
  8. Aerosol fenoterol by intermittent positive pressure breathing in asthmatic patients. Ruffin, R.E., Montgomery, J.M., Newhouse, M.T. Clin. Pharmacol. Ther. (1979) [Pubmed]
  9. Aerosolized terbutaline in asthmatics. Comparison of dosage strength, schedule, and method of administration. Weber, R.W., Petty, W.E., Nelson, H.S. J. Allergy Clin. Immunol. (1979) [Pubmed]
  10. Treatment of laryngotracheobronchitis (croup). Use of intermittent positive-pressure breathing and racemic epinephrine. Taussig, L.M., Castro, O., Beaudry, P.H., Fox, W.W., Bureau, M. Am. J. Dis. Child. (1975) [Pubmed]
  11. Severe acute asthma: a comparison of three methods of inhaling salbutamol. Webber, B.A., Collins, J.V., Branthwaite, M.A. British journal of diseases of the chest. (1982) [Pubmed]
  12. Nebulized salbutamol in life-threatening asthma: is IPPB necessary? Fergusson, R.J., Carmichael, J., Rafferty, P., Willey, R.F., Crompton, G.K., Grant, I.W. British journal of diseases of the chest. (1983) [Pubmed]
  13. Radiographic tracheal diameter measurements in acute infectious croup: an objective scoring system. Corkey, C.W., Barker, G.A., Edmonds, J.F., Mok, P.M., Newth, C.J. Crit. Care Med. (1981) [Pubmed]
  14. Double-blind comparison of metaproterenol and isoetharine-phenylephrine solutions in intermittent positive pressure breathing in bronchospastic conditions. Riker, J.B., Cacace, L.G. Chest (1980) [Pubmed]
  15. Plasma levels of lidocaine following nebulized aerosol administration. Chinn, W.M., Zavala, D.C., Ambre, J. Chest (1977) [Pubmed]
  16. Hypoxemia and hypocarbia following intermittent positive-pressure breathing. Wright, F.G., Foley, M.F., Downs, J.B., Hodges, M.R. Anesth. Analg. (1976) [Pubmed]
  17. Combined topical pulmonary and systemic gentamicin: The question of safety. Lake, K.B., Dyke, J.J., Rumsfeld, J.A. Chest (1975) [Pubmed]
  18. Treatment of acute bronchospasm with beta-adrenergic agonist aerosols delivered by a nasal bilevel positive airway pressure circuit. Pollack, C.V., Fleisch, K.B., Dowsey, K. Annals of emergency medicine. (1995) [Pubmed]
  19. The physiology of mechanical ventilation and the mechanical zoo: IPPB, PEEP, CPAP. Popovich, J. Med. Clin. North Am. (1983) [Pubmed]
  20. Bronchodilatory and circulatory effects of two doses of a beta2-agonist (terbutaline) inhaled with IPPB in patients with reversible airways obstruction. Simonsson, B.G., Svedenblad, H., Ström, B. Scandinavian journal of respiratory diseases. (1976) [Pubmed]
  21. Predictors of patient adherence to long-term home nebulizer therapy for COPD. The IPPB Study Group. Intermittent Positive Pressure Breathing. Turner, J., Wright, E., Mendella, L., Anthonisen, N. Chest (1995) [Pubmed]
  22. Salbutamol delivery during non-invasive mechanical ventilation in patients with chronic obstructive pulmonary disease: a randomized, controlled study. Nava, S., Karakurt, S., Rampulla, C., Braschi, A., Fanfulla, F. Intensive care medicine. (2001) [Pubmed]
  23. Metaproterenol solution in the treatment of asthmatic patients by intermittent positive pressure breathing. Branscomb, B.V. Journal of clinical pharmacology. (1982) [Pubmed]
  24. Comparison of salbutamol given intravenously and by intermittent positive-pressure breathing in life-threatening asthma. Bloomfield, P., Carmichael, J., Petrie, G.R., Jewell, N.P., Crompton, G.K. British medical journal. (1979) [Pubmed]
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