The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Chemical Compound Review

Vectarion     6-[4-[bis(4-fluorophenyl) methyl]piperazin...

Synonyms: CHEMBL314610, AC1L3GFT, AC1Q6WCN, AR-1H0741, LS-155220, ...
This record was replaced with 33887.
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of ALMITRINE


Psychiatry related information on ALMITRINE

  • Almitrine bismesylate increased PaO2 by 8.1 +/- 2.1 mm Hg (mean +/- SEM), decreased arterial carbon dioxide tension by 3.0 +/- 0.7 mm Hg (mean +/- SEM), and increased minute ventilation by 3.1 +/- 0.5 liters/minute (mean +/- SEM) during wakefulness [6].
  • Plasma almitrine bismesylate levels were highly variable, and marked individual differences in peak levels and terminal phase rate constants and half lives were found [7].

High impact information on ALMITRINE


Chemical compound and disease context of ALMITRINE


Biological context of ALMITRINE


Anatomical context of ALMITRINE


Associations of ALMITRINE with other chemical compounds


Gene context of ALMITRINE


Analytical, diagnostic and therapeutic context of ALMITRINE


  1. Peripheral neuropathy in patients treated with almitrine dimesylate. Gherardi, R., Louarn, F., Benvenuti, C., Perrier, M., Lejonc, J.L., Schaeffer, A., Degos, J.D. Lancet (1985) [Pubmed]
  2. The effect of almitrine bismesylate on hypoxemia in chronic obstructive pulmonary disease. Bell, R.C., Mullins, R.C., West, L.G., Bachand, R.T., Johanson, W.G. Ann. Intern. Med. (1986) [Pubmed]
  3. Almitrine bismesylate and hypoxemia. Winkelmann, B.R., Hertrich, F. Ann. Intern. Med. (1987) [Pubmed]
  4. Peripheral nerve function in patients with chronic bronchitis receiving almitrine or placebo. Allen, M.B., Prowse, K. Thorax (1989) [Pubmed]
  5. Almitrine bismesylate and oxygen therapy in hypoxic cor pulmonale. Evans, T.W., Tweney, J., Waterhouse, J.C., Nichol, J., Suggett, A.J., Howard, P. Thorax (1990) [Pubmed]
  6. Long-term effects of almitrine bismesylate on oxygenation during wakefulness and sleep in chronic obstructive pulmonary disease. Gothe, B., Cherniack, N.S., Bachand, R.T., Szalkowski, M.B., Bianco, K.A. Am. J. Med. (1988) [Pubmed]
  7. Effects and handling of almitrine bismesylate in healthy subjects. MacLeod, C.N., Thomas, R.W., Bartley, E.A., Parkhurst, G.W., Bachand, R.T. European journal of respiratory diseases. Supplement. (1983) [Pubmed]
  8. Effects of almitrine bismesylate on the ionic currents of chemoreceptor cells from the carotid body. López-López, J.R., Pérez-García, M.T., Canet, E., Gonzalez, C. Mol. Pharmacol. (1998) [Pubmed]
  9. Comparison of almitrine bismesylate and medroxyprogesterone acetate on oxygenation during wakefulness and sleep in patients with chronic obstructive lung disease. Daskalopoulou, E., Patakas, D., Tsara, V., Zoglopitis, F., Maniki, E. Thorax (1990) [Pubmed]
  10. Almitrine and the peripheral ventilatory response to CO2 in hyperoxia and hypoxia. Olievier, C.N., Berkenbosch, A., DeGoede, J. Respiration physiology. (1989) [Pubmed]
  11. Inhaled NO and almitrine bismesylate in patients with acute respiratory distress syndrome: effect of noradrenalin. Papazian, L., Bregeon, F., Gaillat, F., Thirion, X., Roch, A., Cortes, E., Fulachier, V., Saux, P., Jammes, Y., Auffray, J.P. Eur. Respir. J. (1999) [Pubmed]
  12. Exercise endurance and arterial desaturation in normobaric hypoxia with increased chemosensitivity. Giesbrecht, G.G., Puddy, A., Ahmed, M., Younes, M., Anthonisen, N.R. J. Appl. Physiol. (1991) [Pubmed]
  13. Respiratory muscle recruitment during selective central and peripheral chemoreceptor stimulation in awake dogs. Saupe, K.W., Smith, C.A., Henderson, K.S., Dempsey, J.A. J. Physiol. (Lond.) (1992) [Pubmed]
  14. High-dose almitrine bismesylate inhibits hypoxic pulmonary vasoconstriction in closed-chest dogs. Chen, L., Miller, F.L., Malmkvist, G., Clergue, F.X., Marshall, C., Marshall, B.E. Anesthesiology (1987) [Pubmed]
  15. Additive beneficial effects of the prone position, nitric oxide, and almitrine bismesylate on gas exchange and oxygen transport in acute respiratory distress syndrome. Jolliet, P., Bulpa, P., Ritz, M., Ricou, B., Lopez, J., Chevrolet, J.C. Crit. Care Med. (1997) [Pubmed]
  16. Low dose almitrine bismesylate improves pulmonary gas exchange during canine one-lung hypoxia. Takasaki, M., Oh-Oka, T., Saito, Y., Kosaka, Y. Crit. Care Med. (1989) [Pubmed]
  17. A one year double blind follow-up of blood gas tensions and haemodynamics in almitrine bismesylate therapy. Préfaut, C., Bourgouin-Karaouni, D., Ramonatxo, M., Michel, F.B., Macabies, J. Eur. Respir. J. (1988) [Pubmed]
  18. Almitrine bismesylate and the central and peripheral ventilatory response to CO2. Olievier, C.N., Berkenbosch, A., Degoede, J., Kruyt, E.W. J. Appl. Physiol. (1987) [Pubmed]
  19. Characteristics of augmented breaths provoked by almitrine bismesylate in cats. Szereda-Przestaszewska, M., Jakus, J., Stránsky, A., Baráni, H. Exp. Physiol. (1992) [Pubmed]
  20. Almitrine bismesylate disposition in the human digestive tract. Vidon, N., Chaussade, S., Jeanniot, J.P., Huchet, B., Franchisseur, C., Bernier, J.J. Eur. J. Clin. Pharmacol. (1989) [Pubmed]
  21. Effect of position, nitric oxide, and almitrine on lung perfusion in a porcine model of acute lung injury. Richard, J.C., Janier, M., Lavenne, F., Berthier, V., Lebars, D., Annat, G., Decailliot, F., Guerin, C. J. Appl. Physiol. (2002) [Pubmed]
  22. Effect of arterial chemoreceptor stimulation with almitrine bismesylate on plasma renin activity, aldosterone, ACTH and cortisol in anaesthetized, artificially ventilated cats. Honig, A., Wedler, B., Oppermann, H., Gruska, S., Schmidt, M. Clin. Exp. Pharmacol. Physiol. (1996) [Pubmed]
  23. Plasma vasopressin levels in healthy young men in response to stimulation of the peripheral arterial chemoreceptors by almitrine bismesylate. Honig, A., Landgraf, R., Ledderhos, C., Quies, W. Biomed. Biochim. Acta (1987) [Pubmed]
  24. Influence of infusion of deoxycorticosterone acetate on the responses of kidney function elicited by stimulation of the peripheral arterial chemoreceptors with almitrine bismesylate in anaesthetized rats. Schmidt, M., Ledderhos, C., Kretschmann, B., Schuster, R., Honig, A. Biomed. Biochim. Acta (1987) [Pubmed]
  25. Low-dose almitrine bismesylate in the treatment of hypoxemia due to chronic obstructive pulmonary disease. Winkelmann, B.R., Kullmer, T.H., Kneissl, D.G., Trenk, D., Kronenberger, H. Chest (1994) [Pubmed]
  26. Normotensive normoxic men undergoing water diuresis fail to respond to stimulation of their peripheral arterial chemoreceptors by almitrine with an increase in plasma concentrations of atrial natriuretic factor. Ledderhos, C., Quies, W., Bub, A., Sanchez, R. European journal of applied physiology and occupational physiology. (1992) [Pubmed]
  27. Analysis of almitrine and its metabolites in plasma using on-line fast atom bombardment liquid chromatography/mass spectrometry. Luijten, W., Damien, G., Marchand, B., Capart, J. Biomed. Environ. Mass Spectrom. (1988) [Pubmed]
  28. Dose-response and pharmacokinetic study with almitrine bismesylate after single oral administrations in COPD patients. Bury, T., Jeannot, J.P., Ansquer, J.C., Radermecker, M. Eur. Respir. J. (1989) [Pubmed]
  29. Intubation and mechanical ventilation avoided by using almitrine bismesylate in an acute hypoxemic pneumonia. Muret, J., Clavier, N., Beloucif, S., Payen, D. Intensive care medicine. (1997) [Pubmed]
  30. Effects of combined high-dose partial liquid ventilation and almitrine on pulmonary gas exchange and hemodynamics in an animal model of acute lung injury. Sommerer, A., Dembinski, R., Max, M., Kuhlen, R., Kaisers, U., Rossaint, R. Intensive care medicine. (2001) [Pubmed]
WikiGenes - Universities