Disease relevance of Prone Position

• Influence of prone position on the extent and distribution of lung injury in a high tidal volume oleic acid model of acute respiratory distress syndrome [1].
• Beneficial effects of the prone position on the incidence of barotrauma in oleic acid-induced lung injury under continuous positive pressure ventilation [2].
• The kittens were anesthetized with halothane (1.25-1.50%) at comparable minimum alveolar concentrations and were studied in the prone position during an acute exposure to hyperoxic hypercapnia (8% CO2, 50% O2, balance N2) for 7 min [3].
• Detection of amiodarone-induced pulmonary toxicity in supine and prone positions: high-resolution computed tomography study [4].

High impact information on Prone Position

• Nine infants with documented gastroesophageal reflux participated in 18 paired two-hour postprandial trials in an infant seat and in the horizontal prone position [5].
• CONCLUSION: Maintaining a prone position for 1 hour after an intralumbar dose increased the peak methotrexate concentration and drug exposure in ventricular CSF [6].
• Oxygenation response to a recruitment maneuver during supine and prone positions in an oleic acid-induced lung injury model [7].
• In the presence of abdominal distension, the prone position increased Pa O2 by 26 +/- 18 mm Hg (p < 0.01) and decreased AaPO2 (p < 0.05) and V A/Q heterogeneity as measured by the log standard deviation of the perfusion distribution (p < 0.01) and the arterial-alveolar difference area (p < 0.05) [8].
• Prone position (T3) resulted in an increase in PO2/FI(O2) (193 +/- 83 mm Hg, p < 0.003 versus T0) [9].

Biological context of Prone Position

• RESULTS: The supine position was associated with a higher respiratory rate (p < 0.02) and lower O2 saturation (p < 0.007) than the prone position [10].
• Influence of the prone position on propofol pharmacokinetics [11].
• Haemodynamic effects of the prone position: a comparison of propofol total intravenous and inhalation anaesthesia [12].

Anatomical context of Prone Position

• Forty-two piglets were anesthetized with piritramide, were placed in the prone position, and had the anterior chamber of one eye punctured with a small Teflon cannula to measure IOP [13].
• Anesthetic management of a patient in prone position with a drill bit penetrating the spinal canal at C1-C2, using a laryngeal mask [14].
• In this study, we investigated whether the prone position affects the net balance between pulmonary endothelin (ET-1) and angiotensin II (Ang II) production and clearance, two metabolic functions of lung endothelial cells [15].
• When residual calculi remained in the middle-distal ureter, group 1 subjects underwent subsequent sessions in the ordinary prone position, and Group 1R patients were treated in the rotated-prone position [16].
• Simple celiac and mesenteric arteriography in the prone position with the injection of a large bolus of contrast medium, as fast as possible, is evaluated on the available data against the more complex usual procedure for diagnosing diseases of the pancreas [17].

Associations of Prone Position with chemical compounds

• Hydroxyl free radical formation was significantly higher in the veins of dogs in an upright position than in those in a prone position [18].
• 2. We therefore determined the dynamics of intramuscular [phosphocreatine] ([PCr]) simultaneously with those of .V(O2) in seven males who performed two consecutive bouts of high-intensity square-wave, knee-extensor exercise in the prone position for 6 min with a 6 min rest interval [19].
• TWelve of these patients had massive, bilateral disturbance of intrarenal hippurate transport in the standing position; hippurate transport was normal in the prone position [20].
• METHODS: A polystyrene bowel displacement standard mold was created and added to a customized vacuum cushion (Vac Lok) formed around the abdomen and legs of each patient in the prone position [21].
• CONCLUSION: Perflubron is more uniformly dispersed when dosed in a rotational fashion with alternation between supine and prone position during incremental dosing [22].

Gene context of Prone Position

• Computed tomography (CT) scans were taken in the prone position, both with and without the SBDS [23].
• Thirty-two consecutive patients were studied 1 h before, 1 and 4 h during and 1 h after placing in a prone position with PaO2/F(I)O2 of 103 +/- 28, 158 +/- 62, 159 +/- 59, and 128 +/- 52, respectively (ANOVA, p < 0.001) [24].
• The only variable that was associated with high tryptase values was prone position at death (P < or = 0.05 ) [25].
• Mean (+/-SD) baseline twitch Pga measured with the subjects in the prone position at T10 was 23.5 +/- 5.4 cmH2O [26].
• To evaluate the impact of oxygen therapy on positional effect in gas exchange, arterial blood gas levels were measured in the supine and prone positions in some PAP patients while breathing 40% oxygen [27].

Analytical, diagnostic and therapeutic context of Prone Position

• Within each ventilator group, animals were randomized to supine positioning (S) or rotational positioning with alternation between supine and prone position (R) during incremental dosing of three 5-mL/kg doses of perflubron [22].
• A customized polyurethane and styrofoam bowel immobilization mold was created for each patient in the prone position [28].
• METHODS: Arterial blood gas analysis and measurements of PetCO(2) were carried out during CO(2) insufflation in 16 patients who underwent posterior retroperitoneoscopic adrenalectomy in the prone position (PRA group) [29].
• Capnography measurements included maximal EtCO2, inspired CO2 and frequency of apnoea events (>3 s) in the supine, supine with inclination, side and prone positions [30].
• Myelography for diagnosis requires a specific positioning of the patient with the head fixed in a midline and prone position [31].

References