The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
Chemical Compound Review

Derivative     7-diethylamino-3-(5-phenyl- 1,3,4...

Synonyms: AR-1E1942, AC1L3C2C, AC1Q69VW, EINECS 263-433-6
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

Disease relevance of Derivative

  • Left ventricular (LV) apexcardiogram (ACG) and its first derivative (dA/dt) was obtained in 104 normal subjects and 34 patients with chronic aortic incompetence (AI) [1].
  • The second, DAD, a hybrid series of clones formed between Daudi and a HeLa cell derivative (D98), differed with regard to the expression of EBNA, EA, VCA and the content of EBV DNA [2].
  • Complete 1H- and 13C-NMR Spectral Data of Piloquinone, a 9,10-Phenanthrenequinone Derivative from Streptomyces pilosus [3].
  • In preliminary experiments it had been observed that an immunomodulator isolated from Nocardia bacteria (Nocardia Soluble Peptidoglycan Derivative: NSPD) electively bound to a model of activated macrophages [4].
  • The calibrated left apexcardiogram with time constant 4 s and its first derivative (dA/dt) has been evaluated in 62 patients with ischemic heart disease and in 50 normal subjects [5].
 

Psychiatry related information on Derivative

 

High impact information on Derivative

  • Both probes were split in all eight patients and the two derivative (der) chromosomes were each labeled with both probes [7].
  • Photoreaction of a 2,11-Diaza[3.3]paracyclophane Derivative: Formation of Octahedrane by Photochemical Dimerization of Benzene [8].
  • Pre-steady-State Currents in Neutral Amino Acid Transporters Induced by Photolysis of a New Caged Alanine Derivative [9].
  • RESULTS: Derivative melting curves of the probe-target duplexes were characteristic of the genotype under the probe [10].
  • RNA-PCR revealed the novel chimeric product of EWS/FL11 gene on the derivative chromosome (der) 22, resulting from a probable fusion of EWS exon 7 to FL11 exon 9 [11].
 

Chemical compound and disease context of Derivative

  • The N-Butylcarbamate Derivative of Galantamine Acts as an Allosteric Potentiating Ligand on alpha7 Nicotinic Receptors in Hippocampal Neurons: Clinical Implications for Treatment of Alzheimer's Disease [12].
 

Biological context of Derivative

  • The Ds-controlled allele, bz-m4 Derivative 6856 [bz-m4 D6856], is reported to have an altered temporal- and tissue-specific pattern of gene expression [13].
  • It is assumed that envelope mutations are positively selected because they somehow alleviate the particularly severe inhibition of cell division caused, in strains SB564 and DA78, by the excessive synthesis of hisF and hisH gene products [14].
  • To elucidate the molecular mechanism of the t(2;3)(p11;q27) chromosomal translocation, we compared the structures of both derivative (der) chromosomal breakpoints with those of their germline predecessors [15].
  • Phase plane trajectories were generated by plotting membrane potential (V) versus the first time derivative of membrane potential (dV/dt) [16].
  • Effects of Dietary Intake of a Fungal beta-D-Glucan Derivative on the Level of DNA Damage Induced in Primary Rat Hepatocytes by Various Carcinogens [17].
 

Anatomical context of Derivative

 

Associations of Derivative with other chemical compounds

 

Gene context of Derivative

  • They were generated by using the exon 5' of the breakpoint on der4 as a common splice donor site and the 5' boundaries of exons 8 or 9 of the ALL-1 gene as alternative splice acceptor sites [28].
  • Pharmacokinetics and Metabolism in Mice of IDN 5390 (13-(N-Boc-3-i-butylisoserinoyl)-C-7,8-seco-10-deacetylbaccatin III), a New Oral C-seco-Taxane Derivative with Antiangiogenic Property Effective on Paclitaxel-Resistant Tumors [29].
  • For myopia greater than -1.12 D, the DT algorithm provided a 0% false negative rate [30].
  • When a core-jacket temperature difference is detected, a commercially available analogue PID (Proportional, Integral, Derivative) controller sends to the jacket an amount of electrical power to reduce this difference [31].
  • New Polyphenol Derivative in Ipomoea batatas Tubers and Its Antioxidant Activity [32].
 

Analytical, diagnostic and therapeutic context of Derivative

  • The environment of aromatic aminoacids in the thermal transition of brain tubulin has been studied by several spectroscopic techniques (Fourth Derivative, Difference Absorption, Fluorescence and Circular Dichroism), in order to study its denaturation [33].
  • Cocaine-Benzocaine Mixtures Derivative ultraviolet spectrophotometry has been used for the simultaneous determination of cocaine and benzocaine [34].
  • Negative Ziehl-Nielsen staining for acid fast bacilli and Purified Protein Derivative skin test results were obtained in 32.3% and 11.1% of the examined patients respectively [35].
  • Active tension and its first derivative (dT/dtmax) normalized for muscle cross-sectional area were increased in preparations from the SHR at all ages studied relative to control groups (P less than 0.01) [36].

References

  1. Comparison between apexcardiographic and angiographic indexes of left ventricular performance in patients with aortic incompetence. Manolas, J., Krayenbuehl, H.P. Circulation (1978) [Pubmed]
  2. Somatic cell hybrids between human lymphoma cell lines. V. IdUrd inducibility and P3HR-1 superinfectability of Daudi/HeLa (DAD) and Daudi/P3HR-1 (DIP-1) cell lines. Moar, M.H., Ber, R., Klein, G., Westman, A., Eriksson, I. Int. J. Cancer (1978) [Pubmed]
  3. Complete 1H- and 13C-NMR Spectral Data of Piloquinone, a 9,10-Phenanthrenequinone Derivative from Streptomyces pilosus. Jokela, R., Lounasmaa, M. Planta Med. (1997) [Pubmed]
  4. An original method for submacroscopic metastases visualization in cases of cancer minimal residual disease. Le Pape, A., Barot-Ciorbaru, R., Musset, M., Baulieu, J.L., Jubault, C., Lemarié, E., Pourcelot, L., Besnard, J.C., Nicolau, C., Mathé, G. Biomed. Pharmacother. (1986) [Pubmed]
  5. Clinical value of calibrated and differentiated displacement apexcardiography in ischemic heart disease. Kolev, N.S., Romoda, T. Cardiology (1982) [Pubmed]
  6. Twenty-year tuberculin testing in an institution for persons with mental retardation. Chaney, R.H. Mental retardation. (1989) [Pubmed]
  7. All patients with the T(11;16)(q23;p13.3) that involves MLL and CBP have treatment-related hematologic disorders. Rowley, J.D., Reshmi, S., Sobulo, O., Musvee, T., Anastasi, J., Raimondi, S., Schneider, N.R., Barredo, J.C., Cantu, E.S., Schlegelberger, B., Behm, F., Doggett, N.A., Borrow, J., Zeleznik-Le, N. Blood (1997) [Pubmed]
  8. Photoreaction of a 2,11-Diaza[3.3]paracyclophane Derivative: Formation of Octahedrane by Photochemical Dimerization of Benzene. Okamoto, H., Satake, K., Ishida, H., Kimura, M. J. Am. Chem. Soc. (2006) [Pubmed]
  9. Pre-steady-State Currents in Neutral Amino Acid Transporters Induced by Photolysis of a New Caged Alanine Derivative. Zhang, Z., Papageorgiou, G., Corrie, J.E., Grewer, C. Biochemistry (2007) [Pubmed]
  10. Closed-tube genotyping with unlabeled oligonucleotide probes and a saturating DNA dye. Zhou, L., Myers, A.N., Vandersteen, J.G., Wang, L., Wittwer, C.T. Clin. Chem. (2004) [Pubmed]
  11. Molecular analysis of a t(11;22) translocation junction in a case of Ewing's sarcoma. Bhagirath, T., Abe, S., Nojima, T., Yoshida, M.C. Genes Chromosomes Cancer (1995) [Pubmed]
  12. The N-Butylcarbamate Derivative of Galantamine Acts as an Allosteric Potentiating Ligand on alpha7 Nicotinic Receptors in Hippocampal Neurons: Clinical Implications for Treatment of Alzheimer's Disease. Popa, R.V., Pereira, E.F., Lopes, C., Maelicke, A., Albuquerque, E.X. J. Mol. Neurosci. (2006) [Pubmed]
  13. The mutation bronze-mutable 4 derivative 6856 in maize is caused by the insertion of a novel 6.7-kilobase pair transposon in the untranslated leader region of the bronze-1 gene. Klein, A.S., Clancy, M., Paje-Manalo, L., Furtek, D.B., Hannah, L.C., Nelson, O.E. Genetics (1988) [Pubmed]
  14. Positive selection of mutants with cell envelope defects of a Salmonells typhimurium strain hypersensitive to the products of genes hisF and hisH. Antón, D.N. J. Bacteriol. (1979) [Pubmed]
  15. Variant translocation of the BCL6 gene to immunoglobulin kappa light chain gene in B-cell lymphoma. Suzuki, K., Miki, T., Kawamata, N., Hirosawa, S., Yoshizawa, K., Kiyosawa, K., Aoki, N. Jpn. J. Cancer Res. (1994) [Pubmed]
  16. Early afterdepolarization formation in cardiac myocytes: analysis of phase plane patterns, action potential, and membrane currents. Boutjdir, M., Restivo, M., Wei, Y., Stergiopoulos, K., el-Sherif, N. J. Cardiovasc. Electrophysiol. (1994) [Pubmed]
  17. Effects of Dietary Intake of a Fungal beta-D-Glucan Derivative on the Level of DNA Damage Induced in Primary Rat Hepatocytes by Various Carcinogens. Lazarov??, M., L??baj, J., Eckl, P., Kogan, G., Slamenov??, D. Nutrition and cancer (2006) [Pubmed]
  18. Enamel Matrix Derivative Stimulates Human Gingival Fibroblast Proliferation via ERK. Zeldich, E., Koren, R., Nemcovsky, C., Weinreb, M. J. Dent. Res. (2007) [Pubmed]
  19. Rapid detection of substrate-oxidizing activity of hiochi bacteria using benzoquinone-mediated amperometric method. Kondo, T., Ikeda, T. J. Biosci. Bioeng. (2000) [Pubmed]
  20. Time relation between apex cardiogram and left ventricular events using simultaneous high-fidelity tracings in man. Manolas, J., Rutishauser, W., Wirz, P., Arbenz, U. British heart journal. (1975) [Pubmed]
  21. Protective Effect of Lignophenol Derivative from Beech (Fagus crenata Blume) on Copper- and Zinc-Mediated Cell Death in PC12 Cells. Sato, S., Fujita, S., Funaoka, M., Komori, M., Kurasaki, M. Basic Clin. Pharmacol. Toxicol. (2006) [Pubmed]
  22. Potent Inhibition of Serum-Stimulated Responses in Vascular Smooth Muscle Cell Proliferation by 2-Chloro-3-(4-hexylphenyl)-amino-1,4-naphthoquinone, a Newly Synthesized 1,4-Naphthoquinone Derivative. Kim, T.J., Yun, Y.P. Biol. Pharm. Bull. (2007) [Pubmed]
  23. 1H-NMR and 13C-NMR Assignments of Cryptolepine, A 3:4-Benz-delta-carboline Derivative Isolated from Cryptolepis sanguinolenta. Ablordeppey, S.Y., Hufford, C.D., Borne, R.F., Dwuma-Badu, D. Planta Med. (1990) [Pubmed]
  24. A New Rosmarinic Acid Derivative from Isodon oresbius. Huang, H., Chao, Q.R., Tan, R.X., Sun, H.D., Wang, D.C., Ma, J., Zhao, S.X. Planta Med. (1999) [Pubmed]
  25. A New Oleanic Acid Derivative from Securinega tinctoria. Carvalho, L.M., Seita, J. Planta Med. (1993) [Pubmed]
  26. Echinodol: A New Cembrene Derivative from Echinodorus grandiflorus. Manns, D., Hartmann, R. Planta Med. (1993) [Pubmed]
  27. Naphthoherniarin: An Unusual Coumarin Derivative from Ruta graveolens1. Rózsa, Z., Mester, I., Reisch, J., Szendrei, K. Planta Med. (1989) [Pubmed]
  28. Molecular analysis of the chromosomal breakpoint and fusion transcripts in the acute lymphoblastic SEM cell line with chromosomal translocation t(4;11). Marschalek, R., Greil, J., Löchner, K., Nilson, I., Siegler, G., Zweckbronner, I., Beck, J.D., Fey, G.H. Br. J. Haematol. (1995) [Pubmed]
  29. Pharmacokinetics and Metabolism in Mice of IDN 5390 (13-(N-Boc-3-i-butylisoserinoyl)-C-7,8-seco-10-deacetylbaccatin III), a New Oral C-seco-Taxane Derivative with Antiangiogenic Property Effective on Paclitaxel-Resistant Tumors. Frapolli, R., Marangon, E., Zaffaroni, M., Colombo, T., Falcioni, C., Bagnati, R., Simone, M., D'Incalci, M., Manzotti, C., Fontana, G., Morazzoni, P., Zucchetti, M. Drug Metab. Dispos. (2006) [Pubmed]
  30. Topography-based screening for previous laser in situ keratomileusis to correct myopia. Destrempes, F., Brunette, I., Meunier, J., Beyrouthy, M., Demers, P., Fanous, S., Doyon, G. Journal of cataract and refractive surgery. (2002) [Pubmed]
  31. New constant-temperature operating mode for graphite calorimeter at LNE-LNHB. Daures, J., Ostrowsky, A. Physics in medicine and biology. (2005) [Pubmed]
  32. New Polyphenol Derivative in Ipomoea batatas Tubers and Its Antioxidant Activity. Dini, I., Tenore, G.C., Dini, A. J. Agric. Food Chem. (2006) [Pubmed]
  33. Thermal transitions in the structure of tubulin. Environments of aromatic aminoacids. Mozo-Villarías, A., Morros, A., Andreu, J.M. Eur. Biophys. J. (1991) [Pubmed]
  34. The application of derivative spectrophotometry for the simultaneous determination of cocaine and other local anesthetics. Arufe-Martinez, M.I., Romero-Palanco, J.L., Gamero-Lucas, J., Vizcaya-Rojas, M.A. Journal of analytical toxicology. (1989) [Pubmed]
  35. Adenosine deaminase activity in serum and pleural effusions of tuberculous and non-tuberculous patients. al-Shammary, F.J. Biochem. Mol. Biol. Int. (1997) [Pubmed]
  36. Papillary muscle structure-function relations in the aging spontaneously hypertensive rat. Bing, O.H., Wiegner, A.W., Brooks, W.W., Fishbein, M.C., Pfeffer, J.M. Clinical and experimental hypertension. Part A, Theory and practice. (1988) [Pubmed]
 
WikiGenes - Universities