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Chemical Compound Review

Dilauryl ether     1-dodecoxydodecane

Synonyms: Dodecyl ether, NSC-6816, Lauryl ether, ACMC-209k2d, ANW-30275, ...
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Disease relevance of NSC 6816


High impact information on NSC 6816

  • The preparation solubilized with octaethylene glycol dodecyl ether (C12E8) was purified by successive chromatographies on DEAE-Toyopearl and lentil lectin-Sepharose 4B columns [2].
  • Of the 49 detergents tested for solubilization, optimal crystallization of Ca2+-ATPase was obtained in sarcoplasmic reticulum solubilized with octaethylene glycol dodecyl ether at a detergent/protein weight ratio of 2, and with Brij 36T, Brij 56, and Brij 96 at a detergent/protein ratio of 4 [3].
  • When the cholate-deoxycholate and LiCl-treated membranes of PS3 were solubilized and subjected to ion-exchange chromatography in the presence of octaethyleneglycol dodecyl ether, most of the A-, B-, and C-type cytochromes were copurified as a peak having both quinol-cytochrome c reductase and cytochrome oxidase activities [4].
  • Solubilization of synaptic vesicles in octaethyleneglycol dodecyl ether detergent results in several-fold stimulation of the P-type activity and inactivation of the V-type activity, thus explaining why the V-type activity was not detected previously during purification of the P-type ATPase [5].
  • Fluorescence microscopy showed that, in contrast to the hexyl and dodecyl ether derivatives of HPPH (which localize in mitochondria and lysosomes, respectively), the diketo-analogs and their In(III) complexes localized in Golgi bodies [6].

Biological context of NSC 6816


Anatomical context of NSC 6816


Associations of NSC 6816 with other chemical compounds


Analytical, diagnostic and therapeutic context of NSC 6816


  1. Remarkably enhanced inhibitory effects of hybrid liposomes on the growth of specific tumor cells. Matsumoto, Y., Kato, T., Iseki, S., Suzuki, H., Nakano, K., Iwahara, M., Ueoka, R. Bioorg. Med. Chem. Lett. (1999) [Pubmed]
  2. Purification and reconstitution of an intestinal Na(+)-dependent neutral L-alpha-amino acid transporter. Nakanishi, M., Kagawa, Y., Narita, Y., Hirata, H. J. Biol. Chem. (1994) [Pubmed]
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  4. Identification and properties of a quinol oxidase super-complex composed of a bc1 complex and cytochrome oxidase in the thermophilic bacterium PS3. Sone, N., Sekimachi, M., Kutoh, E. J. Biol. Chem. (1987) [Pubmed]
  5. Cholinergic synaptic vesicles contain a V-type and a P-type ATPase. Yamagata, S.K., Parsons, S.M. J. Neurochem. (1989) [Pubmed]
  6. Photosensitizers derived from 132-oxo-methyl pyropheophorbide-a: enhanced effect of indium(III) as a central metal in in vitro and in vivo photosensitizing efficacy. Rosenfeld, A., Morgan, J., Goswami, L.N., Ohulchanskyy, T., Zheng, X., Prasad, P.N., Oseroff, A., Pandey, R.K. Photochem. Photobiol. (2006) [Pubmed]
  7. Subcellular localization patterns and their relationship to photodynamic activity of pyropheophorbide-a derivatives. MacDonald, I.J., Morgan, J., Bellnier, D.A., Paszkiewicz, G.M., Whitaker, J.E., Litchfield, D.J., Dougherty, T.J. Photochem. Photobiol. (1999) [Pubmed]
  8. Pressure-anesthetic antagonism on the phase separation of non-ionic surfactant micelles. Kaneshina, S., Ueda, I., Kamaya, H., Eyring, H. Biochim. Biophys. Acta (1980) [Pubmed]
  9. Unsaturated aminophospholipids are preferentially retained by the fast skeletal muscle CaATPase during detergent solubilization. Evidence for a specific association between aminophospholipids and the calcium pump protein. Bick, R.J., Youker, K.A., Pownall, H.J., Van Winkle, W.B., Entman, M.L. Arch. Biochem. Biophys. (1991) [Pubmed]
  10. Chemotherapy with hybrid liposomes for lymphoma without drugs in vivo. Nagami, H., Matsumoto, Y., Ueoka, R. International journal of pharmaceutics. (2006) [Pubmed]
  11. A simple peptide mapping method by partial filling micellar electrokinetic capillary chromatography with a zwitterionic-nonionic mixed micelle. Huang, J., Kang, J. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. (2007) [Pubmed]
  12. Characteristics of Wormlike Pentaoxyethylene Decyl Ether C(10)E(5) Micelles Containing n-Dodecanol. Miyake, M., Einaga, Y. The journal of physical chemistry. B, Condensed matter, materials, surfaces, interfaces & biophysical (2007) [Pubmed]
  13. Effects of 1,2-diacylglycerol and cholesterol on the hydrolysis activity of phospholipase D in egg-yolk phosphatidylcholine bilayers. Yamamoto, I., Mazumi, T., Handa, T., Miyajima, K. Biochim. Biophys. Acta (1993) [Pubmed]
  14. Effect of added poly(oxyethylene)dodecyl ether on the phase and rheological behavior of wormlike micelles in aqueous SDS solutions. Acharya, D.P., Sato, T., Kaneko, M., Singh, Y., Kunieda, H. The journal of physical chemistry. B, Condensed matter, materials, surfaces, interfaces & biophysical. (2006) [Pubmed]
  15. State of association of band 3 protein from bovine erythrocyte membrane in nonionic detergent. Nakashima, H., Makino, S. J. Biochem. (1980) [Pubmed]
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