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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
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Disease relevance of Chromatography


High impact information on Chromatography

  • TDF with the specific activity of 2.9 U/mg protein was purified by several chromatographies [6].
  • Using chromatographies to enrich the target and patch clamp to assay the channel activity in liposome-reconstituted fractions, we identified the MscL protein and cloned the mscL gene [7].
  • In these chromatographies, P400 protein co-migrated completely with the InsP3 binding activity [8].
  • The purification scheme includes low salt extraction followed by DEAE-cellulose ion exchange, DNase I-actin affinity, and carboxyl methyl-cellulose ion exchange chromatographies [9].
  • The reconstituted Gbeta5-RGS dimers are similar to the native retinal complex in their behavior on gel-filtration and cation-exchange chromatographies and can be immunoprecipitated with either anti-Gbeta5 or anti-RGS7 antibodies [10].

Chemical compound and disease context of Chromatography


Biological context of Chromatography


Anatomical context of Chromatography


Associations of Chromatography with chemical compounds


Gene context of Chromatography


Analytical, diagnostic and therapeutic context of Chromatography


  1. Novel platelet-agglutinating protein from a thrombotic thrombocytopenic purpura plasma. Siddiqui, F.A., Lian, E.C. J. Clin. Invest. (1985) [Pubmed]
  2. Lysophospholipase of Escherichia coli. Doi, O., Nojima, S. J. Biol. Chem. (1975) [Pubmed]
  3. Purification and properties of alpha-amino-epsilon-caprolactam racemase from Achromobacter obae. Ahmed, S.A., Esaki, N., Soda, K. FEBS Lett. (1982) [Pubmed]
  4. Demonstration of sugar moiety on the surface of hepatitis C virions recovered from the circulation of infected humans. Sato, K., Okamoto, H., Aihara, S., Hoshi, Y., Tanaka, T., Mishiro, S. Virology (1993) [Pubmed]
  5. Unique isozymes of superoxide dismutase in Streptomyces griseus. Youn, H.D., Youn, H., Lee, J.W., Yim, Y.I., Lee, J.K., Hah, Y.C., Kang, S.O. Arch. Biochem. Biophys. (1996) [Pubmed]
  6. Production and characterization of tumor-degenerating factor. Tanaka, A., Matsuoka, H., Uemura, H., Kakui, Y., Imanishi, T., Nishino, H., Imanishi, J. J. Natl. Cancer Inst. (1985) [Pubmed]
  7. Mechanosensitive channels of Escherichia coli: the MscL gene, protein, and activities. Sukharev, S.I., Blount, P., Martinac, B., Kung, C. Annu. Rev. Physiol. (1997) [Pubmed]
  8. A cerebellar Purkinje cell marker P400 protein is an inositol 1,4,5-trisphosphate (InsP3) receptor protein. Purification and characterization of InsP3 receptor complex. Maeda, N., Niinobe, M., Mikoshiba, K. EMBO J. (1990) [Pubmed]
  9. A new 82-kD barbed end-capping protein (radixin) localized in the cell-to-cell adherens junction: purification and characterization. Tsukita, S., Hieda, Y., Tsukita, S. J. Cell Biol. (1989) [Pubmed]
  10. Gbeta5 prevents the RGS7-Galphao interaction through binding to a distinct Ggamma-like domain found in RGS7 and other RGS proteins. Levay, K., Cabrera, J.L., Satpaev, D.K., Slepak, V.Z. Proc. Natl. Acad. Sci. U.S.A. (1999) [Pubmed]
  11. Purification and properties of a novel lipase from Staphylococcus aureus 226. Muraoka, T., Ando, T., Okuda, H. J. Biochem. (1982) [Pubmed]
  12. Purification and characterization of carbaryl hydrolase from Arthrobacter sp. RC100. Hayatsu, M., Mizutani, A., Hashimoto, M., Sato, K., Hayano, K. FEMS Microbiol. Lett. (2001) [Pubmed]
  13. Purification of Streptomyces chromofuscus phospholipase D by hydrophobic affinity chromatography on palmitoyl cellulose. Imamura, S., Horiuti, Y. J. Biochem. (1979) [Pubmed]
  14. Homogeneity of the pyruvate dehydrogenase multienzyme complex from Bacillus stearothermophilus. Hiromasa, Y., Aso, Y., Yamashita, S., Aikawa, Y. J. Biochem. (1995) [Pubmed]
  15. Formaldehyde dehydrogenase from Pseudomonas putida. Purification and some properties. Ando, M., Yoshimoto, T., Ogushi, S., Rikitake, K., Shibata, S., Tsuru, D. J. Biochem. (1979) [Pubmed]
  16. The lymphoma transmembrane glycoprotein GP85 (CD44) is a novel guanine nucleotide-binding protein which regulates GP85 (CD44)-ankyrin interaction. Lokeshwar, V.B., Bourguignon, L.Y. J. Biol. Chem. (1992) [Pubmed]
  17. Synaptotagmin is an inositol polyphosphate binding protein: isolation and characterization as an Ins 1,3,4,5-P4 binding protein. Niinobe, M., Yamaguchi, Y., Fukuda, M., Mikoshiba, K. Biochem. Biophys. Res. Commun. (1994) [Pubmed]
  18. A stimulation factor for hydrolysis of ATP bound to DnaA protein, the initiator of chromosomal DNA replication in Escherichia coli. Kurokawa, K., Mizushima, T., Kubota, T., Tsuchiya, T., Katayama, T., Sekimizu, K. Biochem. Biophys. Res. Commun. (1998) [Pubmed]
  19. Purification of pierisin, an inducer of apoptosis in human gastric carcinoma cells, from cabbage butterfly, Pieris rapae. Watanabe, M., Kono, T., Koyama, K., Sugimura, T., Wakabayashi, K. Jpn. J. Cancer Res. (1998) [Pubmed]
  20. Isolation and characterization of a human alternative complement pathway-inhibiting protein from larval hemolymph of the silkworm, Bombyx mori. Sekijima, Y., Fujikura, Y., Hiyama, T., Maenaka, T., Uda, A. Dev. Comp. Immunol. (2001) [Pubmed]
  21. Human neutrophils release serine proteases capable of activating prorenin. Dzau, V.J., Gonzalez, D., Kaempfer, C., Dubin, D., Wintroub, B.U. Circ. Res. (1987) [Pubmed]
  22. Localization and characterization of gelsolin in nervous tissues: gelsolin is specifically enriched in myelin-forming cells. Tanaka, J., Sobue, K. J. Neurosci. (1994) [Pubmed]
  23. Purification and characterization of a microsomal bile acid beta-glucosidase from human liver. Matern, H., Heinemann, H., Legler, G., Matern, S. J. Biol. Chem. (1997) [Pubmed]
  24. Purification and characterization from rat kidney membranes of a novel platelet-activating factor (PAF)-dependent transacetylase that catalyzes the hydrolysis of PAF, formation of PAF analogs, and C2-ceramide. Karasawa, K., Qiu, X., Lee, T. J. Biol. Chem. (1999) [Pubmed]
  25. Purification of the receptor for platelet-derived growth factor from porcine uterus. Rönnstrand, L., Beckmann, M.P., Faulders, B., Ostman, A., Ek, B., Heldin, C.H. J. Biol. Chem. (1987) [Pubmed]
  26. Purification of a factor capable of stimulating the guanine nucleotide exchange reaction of ras proteins and its effect on ras-related small molecular mass G proteins. Huang, Y.K., Kung, H.F., Kamata, T. Proc. Natl. Acad. Sci. U.S.A. (1990) [Pubmed]
  27. Purification, biochemical characterization, and biological function of human esterase D. Lee, W.H., Wheatley, W., Benedict, W.F., Huang, C.M., Lee, E.Y. Proc. Natl. Acad. Sci. U.S.A. (1986) [Pubmed]
  28. Isolation and characterization of delta-subspecies of protein kinase C from rat brain. Ogita, K., Miyamoto, S., Yamaguchi, K., Koide, H., Fujisawa, N., Kikkawa, U., Sahara, S., Fukami, Y., Nishizuka, Y. Proc. Natl. Acad. Sci. U.S.A. (1992) [Pubmed]
  29. Catabolism of exogenously supplied thymidine to thymine and dihydrothymine by platelets in human peripheral blood. Pero, R.W., Johnson, D., Olsson, A. Cancer Res. (1984) [Pubmed]
  30. Dihydrofolate reductase of the extremely halophilic archaebacterium Halobacterium volcanii. The enzyme and its coding gene. Zusman, T., Rosenshine, I., Boehm, G., Jaenicke, R., Leskiw, B., Mevarech, M. J. Biol. Chem. (1989) [Pubmed]
  31. Corticotropin-induced secreted protein, an ACTH-induced protein secreted by adrenocortical cells, is structurally related to thrombospondins. Pellerin, S., Lafeuillade, B., Scherrer, N., Gagnon, J., Shi, D.L., Chambaz, E.M., Feige, J.J. J. Biol. Chem. (1993) [Pubmed]
  32. Preparation and characterization of recombinant tissue inhibitor of metalloproteinase 4 (TIMP-4). Liu, Y.E., Wang, M., Greene, J., Su, J., Ullrich, S., Li, H., Sheng, S., Alexander, P., Sang, Q.A., Shi, Y.E. J. Biol. Chem. (1997) [Pubmed]
  33. Characterization of a breast cancer cell differentiation factor that specifically activates the HER4/p180erbB4 receptor. Culouscou, J.M., Plowman, G.D., Carlton, G.W., Green, J.M., Shoyab, M. J. Biol. Chem. (1993) [Pubmed]
  34. Human plasma phospholipid transfer protein causes high density lipoprotein conversion. Jauhiainen, M., Metso, J., Pahlman, R., Blomqvist, S., van Tol, A., Ehnholm, C. J. Biol. Chem. (1993) [Pubmed]
  35. An inhibitory insulin-like growth factor binding protein (In-IGFBP) from human prostatic cell conditioned medium reveals N-terminal sequence identity with bone derived In-IGFBP. Perkel, V.S., Mohan, S., Baylink, D.J., Linkhart, T.A. J. Clin. Endocrinol. Metab. (1990) [Pubmed]
  36. Human salivary endo-beta-N-acetylglucosaminidase HS specific for complex type sugar chains of glycoproteins. Ito, K., Okada, Y., Ishida, K., Minamiura, N. J. Biol. Chem. (1993) [Pubmed]
  37. Reversible unfolding of bovine beta-lactoglobulin mutants without a free thiol group. Yagi, M., Sakurai, K., Kalidas, C., Batt, C.A., Goto, Y. J. Biol. Chem. (2003) [Pubmed]
  38. Purification of human factor IX by chromatography of a coagulation factor concentrate. Suomela, H. Thromb. Haemost. (1976) [Pubmed]
  39. A novel phospholipase A2, BJ-PLA2, from the venom of the snake Bothrops jararaca: purification, primary structure analysis, and its characterization as a platelet-aggregation-inhibiting factor. Serrano, S.M., Reichl, A.P., Mentele, R., Auerswald, E.A., Santoro, M.L., Sampaio, C.A., Camargo, A.C., Assakura, M.T. Arch. Biochem. Biophys. (1999) [Pubmed]
  40. Purification of cytoplasmic precursors of yeast mitochondrial phenylalanyl-tRNA synthetase subunits. Diatewa, M., Taite, J.L., Stahl, A.J. Biochem. Biophys. Res. Commun. (1986) [Pubmed]
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