The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Chemical Compound Review

Methylcysteine     (2S)-2-amino-3- methylsulfanyl-propanoic acid

Synonyms: CHEMBL394875, CCRIS 1972, AG-D-41269, AG-H-08911, CHEBI:45658, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of S-Methylcysteine


High impact information on S-Methylcysteine


Biological context of S-Methylcysteine


Anatomical context of S-Methylcysteine

  • The first patient was a "conjugator" with normal glutathone transferase activity, whereas this activity was undetectable in the erythrocytes of the second patient, who consequently had higher concentrations of S-methylcysteine adduct in albumin (149 v 91 nmol/g protein) and in globin (77 v 30 nmol/g protein) [14].
  • N-delta-acetylornithine and S-methylcysteine in blood plasma [15].

Associations of S-Methylcysteine with other chemical compounds


Gene context of S-Methylcysteine


Analytical, diagnostic and therapeutic context of S-Methylcysteine


  1. Repair of alkylated DNA in Escherichia coli. Methyl group transfer from O6-methylguanine to a protein cysteine residue. Olsson, M., Lindahl, T. J. Biol. Chem. (1980) [Pubmed]
  2. Identification of dimethyl disulfide-forming bacteria isolated from activated sludge. Tomita, B., Inoue, H., Chaya, K., Nakamura, A., Hamamura, N., Ueno, K., Watanabe, K., Ose, Y. Appl. Environ. Microbiol. (1987) [Pubmed]
  3. Formation of methionine from alpha-amino-n-butyric acid and 5'-methylthioadenosine in the rat. Edwards, C.H., Wade, W.D., Freeburne, M.M., Jones, E.G., Stacey, R.E., Sherman, L., Seo, C.W., Edwards, G.A. J. Nutr. (1977) [Pubmed]
  4. Substrate specificity of the L-serine O-sulphate degrading activities of Pseudomonas FR. Tudball, N., O'Neill, J.G. Biochim. Biophys. Acta (1976) [Pubmed]
  5. Late confirmation of acute methyl bromide poisoning using S-methylcysteine adduct testing. Buchwald, A.L., Müller, M. Veterinary and human toxicology. (2001) [Pubmed]
  6. Identification and preliminary characterization of an O6-methylguanine DNA repair methyltransferase in the yeast Saccharomyces cerevisiae. Sassanfar, M., Samson, L. J. Biol. Chem. (1990) [Pubmed]
  7. Self-methylation of BspRI DNA-methyltransferase. Szilák, L., Finta, C., Patthy, A., Venetianer, P., Kiss, A. Nucleic Acids Res. (1994) [Pubmed]
  8. In vitro interactions of water-soluble garlic components with human cytochromes p450. Greenblatt, D.J., Leigh-Pemberton, R.A., von Moltke, L.L. J. Nutr. (2006) [Pubmed]
  9. Inhibitory effects of S-methylcysteine and cysteine on the promoting potential of sodium phenobarbital on rat liver carcinogenesis. Vijayaraghavan, M., Wanibuchi, H., Takada, N., Yano, Y., Otani, S., Yamamoto, S., Fukushima, S. Jpn. J. Cancer Res. (2000) [Pubmed]
  10. Identification of thiodiglycolic acid, thiodiglycolic acid sulfoxide, and (3-carboxymethylthio)lactic acid as major human biotransformation products of S-carboxymethyl-L-cysteine. Hofmann, U., Eichelbaum, M., Seefried, S., Meese, C.O. Drug Metab. Dispos. (1991) [Pubmed]
  11. The enantiomer as internal standard for the quantitation of the alkylated amino acid S-methyl-L-cysteine in haemoglobin by gas chromatography-chemical ionisation mass spectrometry with single ion detection. Bailey, E., Farmer, P.B., Lamb, J.H. J. Chromatogr. (1980) [Pubmed]
  12. Studies on the methods for the determination of phosphorylation sites in highly phosphorylated peptides or proteins: phosphorylation sites of hen egg white riboflavin binding protein. Mega, T., Hamazume, Y., Hong, Y.M., Ikenaka, T., Nong, Y.M. J. Biochem. (1986) [Pubmed]
  13. Alkylation of rat serum proteins by dimethylnitrosamine and acetylaminofluorene. Hemminki, K., Savolainen, H. Toxicol. Lett. (1980) [Pubmed]
  14. Glutathione transferase activity and formation of macromolecular adducts in two cases of acute methyl bromide poisoning. Garnier, R., Rambourg-Schepens, M.O., Müller, A., Hallier, E. Occupational and environmental medicine. (1996) [Pubmed]
  15. N-delta-acetylornithine and S-methylcysteine in blood plasma. Armstrong, M.D. Biochim. Biophys. Acta (1979) [Pubmed]
  16. The effect of nitrous oxide-induced inactivation of cobalamin on plasma amino acid levels in the rat. Deacon, R., Jennings, P., Lumb, M., Perry, J., Purkiss, P., Chanarin, I. Scandinavian journal of haematology. (1981) [Pubmed]
  17. Conserved protein TTHA1554 from Thermus thermophilus HB8 binds to glutamine synthetase and cystathionine beta-lyase. Arai, R., Nishimoto, M., Toyama, M., Terada, T., Kuramitsu, S., Shirouzu, M., Yokoyama, S. Biochim. Biophys. Acta (2005) [Pubmed]
  18. Phenylalanine 4-monooxygenase and the S-oxidation of S-carboxymethyl-L-cysteine. Goreish, A.H., Bednar, S., Jones, H., Mitchell, S.C., Steventon, G.B. Drug metabolism and drug interactions. (2004) [Pubmed]
  19. Macromolecular adducts in the use of methyl bromide as fumigant. Goergens, H.W., Hallier, E., Müller, A., Bolt, H.M. Toxicol. Lett. (1994) [Pubmed]
  20. Photolabeling of CheR methyltransferase with S-adenosyl-L-methionine (AdoMet). Studies on the AdoMet binding site. Subbaramaiah, K., Simms, S.A. J. Biol. Chem. (1992) [Pubmed]
  21. A method for the determination of S-methylcysteine by high-performance liquid chromatography: application to the study of carcinogenic methylating agents. Baker, I., Shuker, D.E., Tannenbaum, S.R. J. Chromatogr. (1985) [Pubmed]
WikiGenes - Universities