Chemical Compound Review:
SureCN2671137 [(3S)-oxolan-3-yl] N-[(2S,3S)-4-[(4...
Synonyms:
AC1L9B2S
Pellegrin,
Breilh,
Coureau,
Boucher,
Neau,
Merel,
Lacoste,
Fleury,
Saux,
Pellegrin,
Lazaro,
Dabis,
Thiébaut,
Duval,
Lamotte,
Race,
Descamps,
Damond,
Clavel,
Leport,
Peytavin,
Vilde,
Arvieux,
Tribut,
Schooley,
Clumeck,
Haubrich,
Thompson,
Danner,
van Der Ende,
Sereni,
Antunes,
Blake,
Myers,
Tisdale,
Millard,
Mustafa,
Nacci,
Zhou,
Gurley,
Jarujaron,
Ding,
Fang,
Xu,
Pandak,
Hylemon,
Markland,
Rao,
Parsons,
Black,
Zuchowski,
Tisdale,
Tung,
Masquelier,
Tamalet,
Montès,
Descamps,
Peytavin,
Bocket,
Wirden,
Izopet,
Schneider,
Ferré,
Ruffault,
Palmer,
Trylesinski,
Miller,
Brun-Vézinet,
Costagliola,
Liu,
Johnson,
Ostrow,
Silvestre,
Visscher,
Jacobson,
Wire,
Shelton,
Studenberg,
Tran,
Petersen,
Garrett,
Hee,
Kerr,
Lastere,
Dalban,
Collin,
Descamps,
Girard,
Clavel,
Costagliola,
Brun-Vezinet,
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- Long-term pharmacokinetics of amprenavir in combination with delavirdine in HIV-infected children. Engelhorn, C., Hoffmann, F., Kurowski, M., Stocker, H., Kruse, G., Notheis, G., Belohradsky, B.H., Wintergerst, U. AIDS (2004)
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- Fosamprenavir : clinical pharmacokinetics and drug interactions of the amprenavir prodrug. Wire, M.B., Shelton, M.J., Studenberg, S. Clinical pharmacokinetics. (2006)
- Penetration of enfuvirtide, tenofovir, efavirenz, and protease inhibitors in the genital tract of HIV-1-infected men. Ghosn, J., Chaix, M.L., Peytavin, G., Rey, E., Bresson, J.L., Goujard, C., Katlama, C., Viard, J.P., Tréluyer, J.M., Rouzioux, C. AIDS (2004)
- GF120918, a P-glycoprotein modulator, increases the concentration of unbound amprenavir in the central nervous system in rats. Edwards, J.E., Brouwer, K.R., McNamara, P.J. Antimicrob. Agents Chemother. (2002)
- Amprenavir. Adkins, J.C., Faulds, D. Drugs (1998)
- HIV protease inhibitors activate the unfolded protein response and disrupt lipid metabolism in primary hepatocytes. Zhou, H., Gurley, E.C., Jarujaron, S., Ding, H., Fang, Y., Xu, Z., Pandak, W.M., Hylemon, P.B. Am. J. Physiol. Gastrointest. Liver Physiol. (2006)
- Human immunodeficiency virus protease inhibitors accumulate into cultured human adipocytes and alter expression of adipocytokines. Vernochet, C., Azoulay, S., Duval, D., Guedj, R., Cottrez, F., Vidal, H., Ailhaud, G., Dani, C. J. Biol. Chem. (2005)
- Some HIV protease inhibitors alter lamin A/C maturation and stability, SREBP-1 nuclear localization and adipocyte differentiation. Caron, M., Auclair, M., Sterlingot, H., Kornprobst, M., Capeau, J. AIDS (2003)
- Pharmacokinetics of amprenavir and lopinavir in combination with nevirapine in highly pretreated HIV-infected patients. Fätkenheuer, G., Römer, K., Kamps, R., Salzberger, B., Burger, D. AIDS (2001)
- Pharmacokinetics of amprenavir given once or twice a day when combined with atazanavir in heavily pre-treated HIV-positive patients. Guffanti, M., De Pascalis, C.R., Seminari, E., Fusetti, G., Gianotti, N., Bassetti, D., Galli, A., Castagna, A., Lazzarin, A. AIDS (2003)
- Amprenavir or fosamprenavir plus ritonavir in HIV infection: pharmacology, efficacy and tolerability profile. Arvieux, C., Tribut, O. Drugs (2005)
- HIV protease inhibitors are inhibitors but not substrates of the human breast cancer resistance protein (BCRP/ABCG2). Gupta, A., Zhang, Y., Unadkat, J.D., Mao, Q. J. Pharmacol. Exp. Ther. (2004)
- Oxidative metabolism of amprenavir in the human liver. Effect of the CYP3A maturation. Tréluyer, J.M., Bowers, G., Cazali, N., Sonnier, M., Rey, E., Pons, G., Cresteil, T. Drug Metab. Dispos. (2003)
- Induction of P-glycoprotein and cytochrome P450 3A by HIV protease inhibitors. Huang, L., Wring, S.A., Woolley, J.L., Brouwer, K.R., Serabjit-Singh, C., Polli, J.W. Drug Metab. Dispos. (2001)
- HIV protease inhibitors decrease VEGF/HIF-1alpha expression and angiogenesis in glioblastoma cells. Pore, N., Gupta, A.K., Cerniglia, G.J., Maity, A. Neoplasia (2006)
- Assessment of active transport of HIV protease inhibitors in various cell lines and the in vitro blood--brain barrier. van der Sandt, I.C., Vos, C.M., Nabulsi, L., Blom-Roosemalen, M.C., Voorwinden, H.H., de Boer, A.G., Breimer, D.D. AIDS (2001)
- Interpretation of genotype and pharmacokinetics for resistance to fosamprenavir-ritonavir-based regimens in antiretroviral-experienced patients. Pellegrin, I., Breilh, D., Coureau, G., Boucher, S., Neau, D., Merel, P., Lacoste, D., Fleury, H., Saux, M.C., Pellegrin, J.L., Lazaro, E., Dabis, F., Thiébaut, R. Antimicrob. Agents Chemother. (2007)
- Amprenavir: a review of its clinical potential in patients with HIV infection. Noble, S., Goa, K.L. Drugs (2000)
- Pharmacokinetic Interaction between amprenavir and rifabutin or rifampin in healthy males. Polk, R.E., Brophy, D.F., Israel, D.S., Patron, R., Sadler, B.M., Chittick, G.E., Symonds, W.T., Lou, Y., Kristoff, D., Stein, D.S. Antimicrob. Agents Chemother. (2001)