The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Breath Tests

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Breath Tests


Psychiatry related information on Breath Tests


High impact information on Breath Tests

  • A carbon-13 urea breath test was performed at base line and repeated at 1 and 12 months, and endoscopic biopsy was performed at 12 months to determine H. pylori status [11].
  • We investigated the sucrose-splitting effect of viable yeast cells in eight children with congenital sucrase-isomaltase deficiency, by means of the sucrose hydrogen breath test [12].
  • Letter: H2 breath test for lactase deficiency [13].
  • Bile acid metabolism was also characterized by the breath test for deconjugation using carbon dioxide labeled with radioactive carbon 14 [14].
  • Before and after receiving grapefruit juice, small bowel and colon mucosal biopsies were obtained endoscopically, oral felodipine kinetics were determined, and liver CYP3A4 activity was measured with the [14C N-methyl] erythromycin breath test in each subject [15].

Chemical compound and disease context of Breath Tests


Biological context of Breath Tests


Anatomical context of Breath Tests


Associations of Breath Tests with chemical compounds

  • We conclude that the erythromycin breath test provides a convenient assay of P-450IIIA cytochromes in rats and in some patients [31].
  • Unlike in Europe, the U.S. standard is to use double diagnostics to prove eradication rather than just the urea breath test and to use intent-to-treat rather than assessable patient analyses [32].
  • Letter: Use of aminopyrine in breath tests [33].
  • Lactulose hydrogen breath test in the diagnosis of bacterial overgrowth [34].
  • Based on values in controls, a positive breath test was defined as an increase in breath H2 of greater than or equal to 12 ppm after glucose or greater than or equal to 14 ppm after rice flour [35].

Gene context of Breath Tests


Analytical, diagnostic and therapeutic context of Breath Tests


  1. Abnormal aminopyrine metabolism in patients with hepatic neoplasm. Detection by breath test. Hepner, G.W., Uhlin, S.R., Lipton, A., Harvey, H.A., Rohrer, V. JAMA (1976) [Pubmed]
  2. Aminopyrine N-demethylation by rats with liver cirrhosis. Evidence for the intact cell hypothesis. A morphometric-functional study. Reichen, J., Arts, B., Schafroth, U., Zimmermann, A., Zeltner, B., Zysset, T. Gastroenterology (1987) [Pubmed]
  3. Two-stage triolein breath test differentiates pancreatic insufficiency from other causes of malabsorption. Goff, J.S. Gastroenterology (1982) [Pubmed]
  4. Lactose malabsorption and intolerance and peak bone mass. Di Stefano, M., Veneto, G., Malservisi, S., Cecchetti, L., Minguzzi, L., Strocchi, A., Corazza, G.R. Gastroenterology (2002) [Pubmed]
  5. Triolein breath test: a sensitive and specific test for fat malabsorption. Newcomer, A.D., Hofmann, A.F., DiMagno, E.P., Thomas, P.J., Carlson, G.L. Gastroenterology (1979) [Pubmed]
  6. Verbal dyspraxia and galactosemia. Webb, A.L., Singh, R.H., Kennedy, M.J., Elsas, L.J. Pediatr. Res. (2003) [Pubmed]
  7. 13C-carbohydrate breath tests: impact of physical activity on the rate-limiting step in lactose utilization. Stellaard, F., Koetse, H.A., Elzinga, H., Boverhof, R., Tjoonk, R., Klimp, A., Vegter, D., Liesker, J., Vonk, R.J. Scand. J. Gastroenterol. (2000) [Pubmed]
  8. Small bowel transit time measured by hydrogen breath test in patients with anorexia nervosa. Hirakawa, M., Okada, T., Iida, M., Tamai, H., Kobayashi, N., Nakagawa, T., Fujishima, M. Dig. Dis. Sci. (1990) [Pubmed]
  9. Risk for alcoholism and methadone treatment. A longitudinal study. Marcovici, M., McLellan, A.T., O'Brien, C.P., Rosenzweig, J. J. Nerv. Ment. Dis. (1980) [Pubmed]
  10. Smoking cessation support groups in Israel: a long-term follow-up. Sperber, A.D., Goren-Lerer, M., Peleg, A., Friger, M. Isr. Med. Assoc. J. (2000) [Pubmed]
  11. Absence of benefit of eradicating Helicobacter pylori in patients with nonulcer dyspepsia. Talley, N.J., Vakil, N., Ballard, E.D., Fennerty, M.B. N. Engl. J. Med. (1999) [Pubmed]
  12. Enzyme-substitution therapy with the yeast Saccharomyces cerevisiae in congenital sucrase-isomaltase deficiency. Harms, H.K., Bertele-Harms, R.M., Bruer-Kleis, D. N. Engl. J. Med. (1987) [Pubmed]
  13. Letter: H2 breath test for lactase deficiency. Metz, G., Blendis, L.M., Jenkins, D.J. N. Engl. J. Med. (1976) [Pubmed]
  14. Effect of chenodiol on the small intestine. Unimpaired structure and function during therapy for gallstone dissolution. Casanova, S., Roda, A., Festi, D., Mazzella, G., Aldini, R., Bazzoli, F., Sama, C., Morselli, A.M., Barbara, L., Roda, E. JAMA (1981) [Pubmed]
  15. Grapefruit juice increases felodipine oral availability in humans by decreasing intestinal CYP3A protein expression. Lown, K.S., Bailey, D.G., Fontana, R.J., Janardan, S.K., Adair, C.H., Fortlage, L.A., Brown, M.B., Guo, W., Watkins, P.B. J. Clin. Invest. (1997) [Pubmed]
  16. Malnutrition and carbohydrate malabsorption in children with vertically transmitted human immunodeficiency virus 1 infection. Miller, T.L., Orav, E.J., Martin, S.R., Cooper, E.R., McIntosh, K., Winter, H.S. Gastroenterology (1991) [Pubmed]
  17. Xylose catabolism in the experimental rat blind loop syndrome: studies, including use of a newly developed d-[14C]xylose breath test. Toskes, P.P., King, C.E., Spivey, J.C., Lorenz, E. Gastroenterology (1978) [Pubmed]
  18. Albumin but not fibrinogen synthesis correlates with galactose elimination capacity in patients with cirrhosis of the liver. Ballmer, P.E., Reichen, J., McNurlan, M.A., Sterchi, A.B., Anderson, S.E., Garlick, P.J. Hepatology (1996) [Pubmed]
  19. Comparison of the phenacetin and aminopyrine breath tests: effect of liver disease, inducers and cobaltous chloride. Schoeller, D.A., Kotake, A.N., Lambert, G.H., Krager, P.S., Baker, A.L. Hepatology (1985) [Pubmed]
  20. The onset of sodium retention in experimental cirrhosis in rats is related to a critical threshold of liver function. Wensing, G., Sabra, R., Branch, R.A. Hepatology (1990) [Pubmed]
  21. Helicobacter pylori augments the pH-increasing effect of omeprazole in patients with duodenal ulcer. Labenz, J., Tillenburg, B., Peitz, U., Idström, J.P., Verdú, E.F., Stolte, M., Börsch, G., Blum, A.L. Gastroenterology (1996) [Pubmed]
  22. Measurement of gastric emptying rate of solids by means of a carbon-labeled octanoic acid breath test. Ghoos, Y.F., Maes, B.D., Geypens, B.J., Mys, G., Hiele, M.I., Rutgeerts, P.J., Vantrappen, G. Gastroenterology (1993) [Pubmed]
  23. Factors influencing the eradication of Helicobacter pylori with triple therapy. Graham, D.Y., Lew, G.M., Malaty, H.M., Evans, D.G., Evans, D.J., Klein, P.D., Alpert, L.C., Genta, R.M. Gastroenterology (1992) [Pubmed]
  24. Ursodeoxycholic acid in primary biliary cirrhosis: results of a controlled double-blind trial. Leuschner, U., Fischer, H., Kurtz, W., Güldütuna, S., Hübner, K., Hellstern, A., Gatzen, M., Leuschner, M. Gastroenterology (1989) [Pubmed]
  25. Mitochondrial dysfunction in alcoholic patients as assessed by breath analysis. Lauterburg, B.H., Liang, D., Schwarzenbach, F.A., Breen, K.J. Hepatology (1993) [Pubmed]
  26. Breath-hydrogen test for small-intestinal bacterial colonisation. Metz, G., Gassull, M.A., Drasar, B.S., Jenkins, D.J., Blendis, L.M. Lancet (1976) [Pubmed]
  27. Mixed triglyceride breath test: a noninvasive test of pancreatic lipase activity in the duodenum. Vantrappen, G.R., Rutgeerts, P.J., Ghoos, Y.F., Hiele, M.I. Gastroenterology (1989) [Pubmed]
  28. Taurolithocholate increases heme catabolism and alters the clearance of antipyrine in the rat. Berry, W.R., Kirshenbaum, G., Hoilien, C., Le, M., Reichen, J. Gastroenterology (1985) [Pubmed]
  29. The evolution of changes in quantitative liver function tests in a rat model of biliary cirrhosis: correlation with morphometric measurement of hepatocyte mass. Gross, J.B., Reichen, J., Zeltner, T.B., Zimmermann, A. Hepatology (1987) [Pubmed]
  30. Magnesium hydrogen breath test using end expiratory sampling to assess achlorhydria in pernicious anaemia patients. Humbert, P., López de Soria, P., Fernández-Bañares, F., Juncá, J., Boix, J., Planas, R., Quer, J.C., Domenech, E., Gassull, M.A. Gut (1994) [Pubmed]
  31. Erythromycin breath test as an assay of glucocorticoid-inducible liver cytochromes P-450. Studies in rats and patients. Watkins, P.B., Murray, S.A., Winkelman, L.G., Heuman, D.M., Wrighton, S.A., Guzelian, P.S. J. Clin. Invest. (1989) [Pubmed]
  32. What remaining questions regarding Helicobacter pylori and associated diseases should be addressed by future research? View from North America. Freston, J.W. Gastroenterology (1997) [Pubmed]
  33. Letter: Use of aminopyrine in breath tests. Rosenthal, M. Gastroenterology (1975) [Pubmed]
  34. Lactulose hydrogen breath test in the diagnosis of bacterial overgrowth. Rhodes, J.M., Jewell, D.P. Gastroenterology (1990) [Pubmed]
  35. Breath hydrogen testing in bacterial overgrowth of the small intestine. Kerlin, P., Wong, L. Gastroenterology (1988) [Pubmed]
  36. The caffeine breath test does not identify patients susceptible to tacrine hepatotoxicity. Fontana, R.J., Turgeon, D.K., Woolf, T.F., Knapp, M.J., Foster, N.L., Watkins, P.B. Hepatology (1996) [Pubmed]
  37. Gastrointestinal regulatory peptides in systemic sclerosis. Akesson, A., Ekman, R. Arthritis Rheum. (1993) [Pubmed]
  38. Factors affecting cytochrome P-450 3A activity in cancer patients. Baker, S.D., van Schaik, R.H., Rivory, L.P., Ten Tije, A.J., Dinh, K., Graveland, W.J., Schenk, P.W., Charles, K.A., Clarke, S.J., Carducci, M.A., McGuire, W.P., Dawkins, F., Gelderblom, H., Verweij, J., Sparreboom, A. Clin. Cancer Res. (2004) [Pubmed]
  39. Variation in oral clearance of saquinavir is predicted by CYP3A5*1 genotype but not by enterocyte content of cytochrome P450 3A5. Mouly, S.J., Matheny, C., Paine, M.F., Smith, G., Lamba, J., Lamba, V., Pusek, S.N., Schuetz, E.G., Stewart, P.W., Watkins, P.B. Clin. Pharmacol. Ther. (2005) [Pubmed]
  40. Interpatient heterogeneity in expression of CYP3A4 and CYP3A5 in small bowel. Lack of prediction by the erythromycin breath test. Lown, K.S., Kolars, J.C., Thummel, K.E., Barnett, J.L., Kunze, K.L., Wrighton, S.A., Watkins, P.B. Drug Metab. Dispos. (1994) [Pubmed]
  41. A sensitive and specific serologic test for detection of Campylobacter pylori infection. Evans, D.J., Evans, D.G., Graham, D.Y., Klein, P.D. Gastroenterology (1989) [Pubmed]
  42. The diagnosis of small bowel bacterial overgrowth. Reliability of jejunal culture and inadequacy of breath hydrogen testing. Corazza, G.R., Menozzi, M.G., Strocchi, A., Rasciti, L., Vaira, D., Lecchini, R., Avanzini, P., Chezzi, C., Gasbarrini, G. Gastroenterology (1990) [Pubmed]
  43. Quantitative assessment of hepatic function by breath analysis after oral administration of (14C)aminopyrine. Hepner, G.W., Vesell, E.S. Ann. Intern. Med. (1975) [Pubmed]
  44. The aminopyrine breath test predicts the outcome of hepatic transplantation in pigs. Oakland, C.D., Hickman, R., Terblanche, J. Hepatology (1989) [Pubmed]
  45. Long term serological surveillance after treatment of Helicobacter pylori infection. Veenendaal, R.A., Peña, A.S., Meijer, J.L., Endtz, H.P., van der Est, M.M., van Duijn, W., Eulderink, F., Kreuning, J., Lamers, C.B. Gut (1991) [Pubmed]
WikiGenes - Universities