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Chemical Compound Review

Desacetylcefotaxime     (6R,7R)-7-[[(2Z)-2-(2-amino- 1,3-thiazol-4...

Synonyms:
 
 
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Disease relevance of Desacetylcefotaxime

 

High impact information on Desacetylcefotaxime

 

Chemical compound and disease context of Desacetylcefotaxime

 

Biological context of Desacetylcefotaxime

 

Anatomical context of Desacetylcefotaxime

 

Associations of Desacetylcefotaxime with other chemical compounds

 

Gene context of Desacetylcefotaxime

 

Analytical, diagnostic and therapeutic context of Desacetylcefotaxime

References

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  2. In vitro activity of desacetylcefotaxime and the interaction with its parent compound, cefotaxime. Oizumi, K., Hayashi, I., Aonuma, S., Konno, K. Drugs (1988) [Pubmed]
  3. Cefotaxime and desacetylcefotaxime pharmacokinetics in infants and children with meningitis. Trang, J.M., Jacobs, R.F., Kearns, G.L., Brown, A.L., Wells, T.G., Underwood, F.L., Kluza, R.B. Antimicrob. Agents Chemother. (1985) [Pubmed]
  4. Serum and tissue concentrations of cefoxitin and cefotaxime in women undergoing hysterectomy. White, R.L., Nightingale, C.H., Quintiliani, R., Whitaker, K.F., Jones, R.F., Tripp, W.H. Drugs (1988) [Pubmed]
  5. Pharmacokinetics of intravenous and intraperitoneal cefotaxime in chronic ambulatory peritoneal dialysis. Albin, H.C., Demotes-Mainard, F.M., Bouchet, J.L., Vincon, G.A., Martin-Dupont, C. Clin. Pharmacol. Ther. (1985) [Pubmed]
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  7. Pharmacokinetics of cefotaxime and desacetylcefotaxime in patients with liver disease. Ko, R.J., Sattler, F.R., Nichols, S., Akriviadis, E., Runyon, B., Appleman, M., Cohen, J.L., Koda, R.T. Antimicrob. Agents Chemother. (1991) [Pubmed]
  8. Penetration of cefotaxime and desacetylcefotaxime into brain abscesses in humans. Sjölin, J., Eriksson, N., Arneborn, P., Cars, O. Antimicrob. Agents Chemother. (1991) [Pubmed]
  9. Escherichia coli resistant to cephalosporins and quinolones is still susceptible to the cephalosporin-quinolone ester Ro 23-9424. Pace, J., Bertasso, A., Georgopapadakou, N.H. Antimicrob. Agents Chemother. (1991) [Pubmed]
  10. Protocol for the study of drug interferences in laboratory tests: cefotaxime interference in 24 clinical tests. Baer, D.M., Jones, R.N., Mullooly, J.P., Horner, W. Clin. Chem. (1983) [Pubmed]
  11. Antimicrobial activity of Ro 24-6778, a covalent bonding of desmethylfleroxacin and desacetylcefotaxime. Jones, R.N. Diagn. Microbiol. Infect. Dis. (1990) [Pubmed]
  12. Antimicrobial interactions (synergy) of teicoplanin with two broad-spectrum drugs (cefotaxime, ofloxacin) tested against gram-positive isolates from Germany and the United States. Jones, R.N., Marshall, S.A., Grimm, H. Diagn. Microbiol. Infect. Dis. (1997) [Pubmed]
  13. Perioperative pharmacokinetics of cefotaxime in serum and bile during continuous and intermittent infusion in liver transplant patients. Buijk, S.E., Gyssens, I.C., Mouton, J.W., Metselaar, H.J., Groenland, T.H., Verbrugh, H.A., Bruining, H.A. J. Antimicrob. Chemother. (2004) [Pubmed]
  14. Cefotaxime pharmacokinetics and treatment of meningitis in neonates. Jacobs, R.F., Kearns, G.L. Infection (1989) [Pubmed]
  15. Disposition of cefotaxime and its metabolite, desacetylcefotaxime, in rat: application of a pharmacokinetic-protein binding model. Hakim, L., Bourne, D.W., Triggs, E.J. Xenobiotica (1989) [Pubmed]
  16. Serum and renal tissue concentrations of cefotaxime in urinary tract obstruction in rabbits. Tago, K., Yabusaki, N., Ueno, A. Drugs (1988) [Pubmed]
  17. Comparative perilymph permeability of cephalosporins and its significance in the treatment and prevention of suppurative labyrinthitis. Sun, A.H., Parnes, L.S., Freeman, D.J. The Annals of otology, rhinology, and laryngology. (1996) [Pubmed]
  18. In vivo evaluation of a dual-action antibacterial, Ro 23-9424, compared to cefotaxime and fleroxacin. Beskid, G., Siebelist, J., McGarry, C.M., Cleeland, R., Chan, K., Keith, D.D. Chemotherapy. (1990) [Pubmed]
  19. In vitro activity of Ro 24-6392, a novel ester-linked co-drug combining ciprofloxacin and desacetylcefotaxime. Jones, R.N. Eur. J. Clin. Microbiol. Infect. Dis. (1990) [Pubmed]
  20. An in vitro study of the interaction between cefotaxime and desacetylcefotaxime. Winstanley, T.G., Spencer, R.C. Drugs under experimental and clinical research. (1986) [Pubmed]
  21. Evaluation of cefotaxime alone and in combination with desacetylcefotaxime against strains of Staphylococcus aureus that produce variants of staphylococcal beta-lactamase. Stratton, C.W., Kernodle, D.S., Eades, S.C., Weeks, L.S. Diagn. Microbiol. Infect. Dis. (1989) [Pubmed]
  22. The in vitro antimicrobial activity of desacetylcefotaxime compared to other related beta-lactams. Schrinner, E., Limbert, M., Seeger, K., Seibert, G., Novick, W.J. Diagn. Microbiol. Infect. Dis. (1984) [Pubmed]
  23. Cefotaxime and metabolite disposition in two pediatric continuous ambulatory peritoneal dialysis patients. Paap, C.M., Nahata, M.C., Mentser, M.A., Mahan, J.D., Puri, S.K., Hubbard, J.A. The Annals of pharmacotherapy. (1992) [Pubmed]
  24. Synergistic interaction between ofloxacin and cefotaxime against common clinical pathogens. Jenkins, S.G., Lewis, J.W. Infection (1995) [Pubmed]
 
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