Disease relevance of Meerschaum

• Mineral fiber-related pleural diseases were not detected in those people who were exposed to sepiolite dust [1].
• Although pulmonary fibrosis was encountered in 10 of 63 workers, no relationship between pulmonary fibrosis and sepiolite inhalation could be established [1].
• The four types of sepiolite were strongly hemolytic, but their cell toxicity and clastogenicity varied according to their grade of crystallinity and/or fiber size [2].

High impact information on Meerschaum

• Implantation of sepiolite-collagen complexes in surgically created rat calvaria defects [3].
• Cell morphology, proliferation and collagen synthesis of human fibroblasts cultured on sepiolite-collagen complexes [4].
• The studies reported here are part of a series of experiments designed to characterize connective tissue cell response to sepiolite (magnesium silicate)-collagen complexes [5].
• Effects of ionic strength, pH, organic content, cell concentration, and growth phase on the removal of MA cells using chitosan-modified sepiolite were studied in the laboratory [6].
• The high efficiency for sepiolite to flocculate M. aeruginosa cells in freshwaters was due to the mechanism of netting and bridging effect [7].

Biological context of Meerschaum

• The purpose of the present work was to compare the bioavailability of structural fluorine contained in sepiolite and in sodium fluoride for laying hens [8].
• Enzymes (beta-glucanase and arabinoxylanase) and/or sepiolite supplementation and the nutritive value of maize-barley-wheat based diets for broiler chickens [9].
• Since there is evidence suggesting that sepiolite is fibrogenic and carcinogenic, its potential occurrence in consumer talcs and crushed-stone products has environmental health implications [10].
• Sepiolite was unreactive in two of the three tests we used (complement activation and ROS production) and able to lyse a minimal percentage of red blood cells [11].

Anatomical context of Meerschaum

• Outgrowth of fibroblasts on sepiolite-collagen complex [5].
• Sepiolite inclusion significantly reduced the viscosity of jejunum digesta and modified the retention times of digesta in the gut, depending upon whether enzymes had been added [9].

Associations of Meerschaum with other chemical compounds

• The results indicate that 2-aminopyridine and 2,2'-bipyridyl molecules adsorb onto sepiolite through hydrogen bonding of the amino groups to the water molecules in the octahedral sheet and to the surface hydroxyls (Si-OH) in the tetrahedral sheet [12].
• In vitro affinity tests were conducted to test the effectiveness of 19 activated carbons (ACs), hydrates sodium calcium aluminosilicate (HSCAS) and sepiolite (S) in binding ochratoxin A (OA) and deoxynivalenol (DON) from solution [13].
• Bioavailability of fluoride from dietary sepiolite in the lamb [14].
• A kinetic study of the anaerobic digestion of soft drink wastewater was undertaken, using bioreactors containing various suspended supports (bentonite, zeolite, sepiolite, saponite and polyurethane foam), on to which the microorganisms effecting the purification were immobilized [15].
• Multinuclear magnetic resonance spectroscopy studies of the structuration of the tunnels of sepiolite in the presence of intracrystalline pyridine molecules [16].

Gene context of Meerschaum

• 6. The zeta potential for the sepiolite has ranged from +23.3 mV at pH approximately 2 to -22.4 mV at pH approximately 8 at 20 +/- 2 degrees C in water [17].
• In a wider context, sepiolite may be expected to precipitate at the end-stages of hydrothermal mineralization in some talc deposits and in carbonate and calc-silicate rocks [10].
• Some clay minerals occur naturally in a fibrous or lath-like crystal state as attapulgite and sepiolite [18].
• Adsorption of Acid Red 57 from aqueous solutions onto surfactant-modified sepiolite [19].
• The adsorption capacities of natural sepiolite and DEDMA-sepiolite at pH 1.5 and 20 degrees C were (1.19 and 2.57) x 10(-4) mol g(-1), respectively [20].

Analytical, diagnostic and therapeutic context of Meerschaum

• This paper reports a cross sectional study of the total work force of the largest sepiolite production plant in the world [21].
• The surface modification of surfactant-modified sepiolite was controlled using the FTIR technique [19].
• Type I collagen from calf skin interacts with magnesium silicate (sepiolite) resulting in a collagen-clay complex which is separated by centrifugation [22].

References