Disease relevance of Environmental Health

• Short articles on the following topics: *NIEHS Strategic Plan: New Frontiers in Environmental Sciences and Human Health; Beyond the Bench: Environmental Health Nursing: Putting Knowledge into Practice; Headliners: Inhibition of RLIP76 Causes Complete Regression of Melanoma in Mice [1].
• With a $1-million contribution from the Nova Scotia government, Dalhousie University medical school is establishing an environmental health clinic that will research and treat the controversial condition known as multiple-chemical sensitivity [2].
• Lead poisoning is an important environmental health problem, and physicians must be aware of the endocrine disorders such as hyperthyroidism and hyperparathyroidism that increase bone turnover, favouring lead mobilisation [3].
• Three specific examples concerning the environmental health implications of black skin, heat stress adaptation, and G-6-PD deficiency have been discussed in which evolutionary theory provides the conceptual framework for novel insights and reasonable predictions of environment, pollutant and human interactions [4].

High impact information on Environmental Health

• Improving the U.S. EPA Toxic Release Inventory database for environmental health research [5].
• Five to six individual kidney samples of the same experimental group were pooled together, and quadruplicate hybridizations were performed using the National Institute of Environmental Health Sciences Rat version 2.0 Chip, which contains approximately 6,700 genes [6].
• Norton Nelson's legacy: the science of environmental health [7].
• Together with evidence of low levels of atrazine impairing amphibian gonadal development, the results here raise concerns about the role of atrazine in amphibian declines and highlight the importance of considering persistent, postexposure effects when evaluating the impact of xenobiotics on environmental health [8].
• In this study we used quantitative reverse transcription-polymerase chain reaction (qRT-PCR) to investigate discrepant results between the National Institute of Environmental Health Sciences cDNA and Affymetrix oligo platforms used to evaluate hepatic gene expression changes in rats exposed to methapyrilene [9].

Chemical compound and disease context of Environmental Health

• The Spirostomum ambiguum toxicity test has been intensively studied in the Department of Environmental Health Sciences, Warsaw University of Medicine for the last 5 years [10].

Biological context of Environmental Health

• The Boston Public Health Commission's Environmental Health Office, with local and national partners, created the Boston Mercury Thermometer Exchange Program to address this hazard [11].
• The status and projected utility of four biomarker studies conducted by NRC and sponsored by ATSDR, the Environmental Protection Agency (EPA), and the National Institute of Environmental Health Sciences (NIEHS) are discussed [12].
• Mercury is a major issue in environmental health, as it can be biotransformed to methylmercury, accumulate into aquatic organisms, and enter the food chain [13].
• In environmental health, inhalation is the most prominent route of ethylene oxide (EO) exposure [14].
• Within preventive medicine there are three areas: Aerospace Medicine, Occupational Medicine, and Public Health/General Preventive Medicine. The preventive medicine specialties have a common core of required training including biostatistics, epidemiology, health services administration and environmental health [15].

Anatomical context of Environmental Health

• To avoid interference with thyroid function, the California Office of Environmental Health Hazard Assessment recommended a public health goal of 6 microg perchlorate per liter of drinking water, but approximately three times that concentration is likely to be safe [16].
• The panel convened for the Technical Workshop on Human Milk Surveillance and Biomonitoring for Environmental Chemicals in the United States, held at the Hershey Medical Center, Pennsylvania State College of Medicine, on 24--26 September 2004, considered how human milk research may contribute to environmental health initiatives to benefit society [17].

Associations of Environmental Health with chemical compounds

• Pfiesteria: review of the science and identification of research gaps. Report for the National Center for Environmental Health, Centers for Disease Control and Prevention [18].
• Proceedings of the WHO-NIEHS conference on potential environmental health hazards from technological developments in rubber and plastics industries. Research Triangle Park, N.C., March 1-3, 1976: Concluding remarks [19].
• Their mission: to explore the possibility of launching a joint research program to study the human and environmental health effects resulting from spraying Agent Orange and other herbicides during the Vietnam War [20].
• Thermal removal of pyrene contamination from soil: basic studies and environmental health implications [21].
• A set of 93 differentially expressed genes associated with cisplatin-induced renal injury was identified on the National Institute of Environmental Health Sciences (NIEHS) custom cDNA microarray platform using quadruplicate measurements of pooled animal RNA [22].

Gene context of Environmental Health

• AIM: The aim of this paper is to introduce the integrative model of environmental health and explore its potential to illuminate the Toronto SARS experience [23].
• This study also confirms projections made in 2000 by the President's Task Force on Environmental Health Risks and Safety Risks to Children of the number of houses with lead-based paint hazards [24].
• The magnitude of the environmental health problems in peri-urban settlements, however, has exceeded the capacity of DIGESA to respond [25].
• In this review, we summarize recent developments in p53 biomarker research and illustrate applications to environmental health [26].
• Our results provide a rationale for assessing hematologic parameters in occupationally exposed individuals, and indicate the need to determine both the mechanism and the environmental health consequences of the observed hematopoietic effects [27].

Analytical, diagnostic and therapeutic context of Environmental Health

• The recent National Institute of Environmental Health Sciences/National Toxicology Program Carcinogen Prediction Challenge elicited a valuable array of predictions of the carcinogenicity of chemicals tested in the lifetime rodent bioassay [28].
• SETTING:: Department of Rehabilitation Medicine, University of Occupational and Environmental Health, Japan. RESULTS: Right triceps brachii MVCs of the marathoners (42.4 +/- 8.8 N m (range 33-55 N m)) and recreational athletes (41.6 +/- 9.3 N m (range 32-56 N m)) did not differ significantly (P = 0.63) [29].

References