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MeSH Review

Pleural Diseases

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Disease relevance of Pleural Diseases


High impact information on Pleural Diseases


Chemical compound and disease context of Pleural Diseases

  • A counter hypothesis, based on the detection of very small quantities of chrysotile and tremolite in strata samples and human lung tissue, postulates a significant role of these minerals as one of several factors contributing to pleural disease [11].
  • METHODS: The Japan Clinical Oncology Group conducted a phase III trial for a 3-year period starting from October 1994 to determine whether intraoperative intrapleural hypotonic cisplatin treatment could effectively control pleural disease and thereby prolong the survival of these patients [12].
  • Abnormalities of pulmonary function and pleural disease among titanium metal production workers [13].
  • Mineral fiber-related pleural diseases were not detected in those people who were exposed to sepiolite dust [14].
  • 0. Because of the high predictive values of the test, measurement of lactate concentration in pleural fluid offers a rapid and useful information in the differentiation between infectious and non-infectious pleural disease [15].

Anatomical context of Pleural Diseases


Gene context of Pleural Diseases

  • It is unlikely that TNF alpha is the sole stimulus for the IL-8 production in pleural disease states [19].
  • Paired pleural fluid and serum CEA determinations were performed in 107 patients, 53 with malignant and 54 with non-malignant pleural disease [20].
  • Physicians treating patients with COPD and associated pleural disease should be aware of this rare condition, since percutaneous needle drainage may be associated with serious life-threatening complications [21].
  • In many effusions in this study, a concomitant T-lymphocytosis was observed with a non-specific increase in the CD4/CD8 ratio, as known for other pleural diseases [22].
  • Serum and pleural fluid levels of orosomucoid, alpha 2-macroglobulin, IgG, IgA, and IgM were measured in 36, 29, and nine patients suffering from malignant, tuberculous, and non-malignant, non-inflammatory pleural disease, respectively [23].

Analytical, diagnostic and therapeutic context of Pleural Diseases


  1. Expression of glycoprotein 90K in human malignant pleural mesothelioma: correlation with patient survival. Strizzi, L., Muraro, R., Vianale, G., Natoli, C., Talone, L., Catalano, A., Mutti, L., Tassi, G., Procopio, A. J. Pathol. (2002) [Pubmed]
  2. Chest pain in asbestos-exposed individuals with benign pleural and parenchymal disease. Mukherjee, S., de Klerk, N., Palmer, L.J., Olsen, N.J., Pang, S.C., William Musk, A. Am. J. Respir. Crit. Care Med. (2000) [Pubmed]
  3. Manganese superoxide dismutase in healthy human pleural mesothelium and in malignant pleural mesothelioma. Kahlos, K., Anttila, S., Asikainen, T., Kinnula, K., Raivio, K.O., Mattson, K., Linnainmaa, K., Kinnula, V.L. Am. J. Respir. Cell Mol. Biol. (1998) [Pubmed]
  4. Interleukin-1 beta in pleural fluids of different etiologies. Its role as inflammatory mediator in empyema. Silva-Mejías, C., Gamboa-Antiñolo, F., López-Cortés, L.F., Cruz-Ruiz, M., Pachón, J. Chest (1995) [Pubmed]
  5. Basic fibroblast growth factor in mesothelioma pleural effusions: correlation with patient survival and angiogenesis. Strizzi, L., Vianale, G., Catalano, A., Muraro, R., Mutti, L., Procopio, A. Int. J. Oncol. (2001) [Pubmed]
  6. Effects of intrapleural heparin or urokinase on the extent of tetracycline-induced pleural disease. Strange, C., Baumann, M.H., Sahn, S.A., Idell, S. Am. J. Respir. Crit. Care Med. (1995) [Pubmed]
  7. Non-small cell lung cancer: evaluation of pleural abnormalities on CT scans with 18F FDG PET. Schaffler, G.J., Wolf, G., Schoellnast, H., Groell, R., Maier, A., Smolle-Jüttner, F.M., Woltsche, M., Fasching, G., Nicoletti, R., Aigner, R.M. Radiology. (2004) [Pubmed]
  8. Tenascin and fibronectin expression in human mesothelial cells and pleural mesothelioma cell-line cells. Kinnula, V.L., Linnala, A., Viitala, E., Linnainmaa, K., Virtanen, I. Am. J. Respir. Cell Mol. Biol. (1998) [Pubmed]
  9. Interleukin 6 is an autocrine growth factor for normal human pleural mesothelial cells. Fujino, S., Yokoyama, A., Kohno, N., Hiwada, K. Am. J. Respir. Cell Mol. Biol. (1996) [Pubmed]
  10. Gallium-67 thoracic scan and pleural disease in asbestos workers. Lambert, R., Bisson, G., Lamoureux, G., Bégin, R. J. Nucl. Med. (1985) [Pubmed]
  11. In vitro genotoxic activities of fibrous erionite. Poole, A., Brown, R.C., Turver, C.J., Skidmore, J.W., Griffiths, D.M. Br. J. Cancer (1983) [Pubmed]
  12. A prematurely terminated phase III trial of intraoperative intrapleural hypotonic cisplatin treatment in patients with resected non-small cell lung cancer with positive pleural lavage cytology: the incidence of carcinomatous pleuritis after surgical intervention. Ichinose, Y., Tsuchiya, R., Koike, T., Yasumitsu, T., Nakamura, K., Tada, H., Yoshimura, H., Mitsudomi, T., Nakagawa, K., Yokoi, K., Kato, H. J. Thorac. Cardiovasc. Surg. (2002) [Pubmed]
  13. Abnormalities of pulmonary function and pleural disease among titanium metal production workers. Garabrant, D.H., Fine, L.J., Oliver, C., Bernstein, L., Peters, J.M. Scandinavian journal of work, environment & health. (1987) [Pubmed]
  14. Clinical and radiological study in sepiolite workers. Baris, Y.I., Sahin, A.A., Erkan, M.L. Arch. Environ. Health (1980) [Pubmed]
  15. Diagnostic significance of pleural fluid lactate concentration in pleural and pulmonary diseases. Gästrin, B., Lövestad, A. Scand. J. Infect. Dis. (1988) [Pubmed]
  16. Stiffness of the rib cage in a subset of rheumatoid patients. Bégin, R., Radoux, V., Cantin, A., Ménard, H.A. Lung (1988) [Pubmed]
  17. Evaluation of adenosine deaminase activity in the Mycobacterium tuberculosis culture supernatants. Bañales, J.L., Rivera-Martínez, E., Pérez-González, L., Selman, M., Raymond, Y., Nava, A. Arch. Med. Res. (1999) [Pubmed]
  18. Eotaxin levels in pleural effusions: comparison with monocyte chemoattractant protein-1 and IL-8. Yokoyama, A., Kohno, N., Ito, M., Abe, M., Hiwada, K., Yamada, H., Matsushima, K., Hirai, K. Intern. Med. (2000) [Pubmed]
  19. Interleukin-8: an important neutrophil chemotaxin in some cases of exudative pleural effusions. Miller, E.J., Idell, S. Exp. Lung Res. (1993) [Pubmed]
  20. Simultaneous enzyme immunoassay of carcinoembryonic antigen in pleural effusion and serum. Asseo, P.P., Tracopoulos, G.D. Am. J. Clin. Pathol. (1982) [Pubmed]
  21. Loculated hemopneumothorax of a major fissure in patients with COPD and associated pleural disease. Kollef, M.H. Chest (1990) [Pubmed]
  22. Immunocytology in malignant pleural mesothelioma. Expression of tumor markers and distribution of lymphocyte subsets. Guzman, J., Bross, K.J., Würtemberger, G., Costabel, U. Chest (1989) [Pubmed]
  23. Orosomucoid, alpha 2-macroglobulin and immunoglobulins in serum and pleural effusions. Asseo, P.P., Tracopoulos, G.D. Am. J. Clin. Pathol. (1981) [Pubmed]
  24. Carcinoembryonic antigen in pleural effusions. Diagnostic value in malignant mesothelioma. Faravelli, B., D'Amore, E., Nosenzo, M., Betta, P.G., Donna, A. Cancer (1984) [Pubmed]
  25. Combination intracavitary chemotherapy for malignant pleural disease. Markman, M., Howell, S.B., Green, M.R. Cancer drug delivery. (1984) [Pubmed]
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